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List of works by Gary S Shaw

A disease state mutation unfolds the parkin ubiquitin-like domain.

scientific article published on 16 November 2007

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease ⬇️

scientific article published on January 1, 2013

A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex

scientific article

A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form

scientific article

A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination

scientific article published on 24 January 2014

A subset of calcium-binding S100 proteins show preferential heterodimerization

scientific article published on 21 February 2019

Amide exchange shows calcium-induced conformational changes are transmitted to the dimer interface of S100B.

scientific article

Architecture of the catalytic HPN motif is conserved in all E2 conjugating enzymes

scientific article published on 01 July 2012

Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin.

scientific article

Ataxin-3 is a multivalent ligand for the parkin Ubl domain

scientific article

Autoregulation of Parkin activity through its ubiquitin-like domain

scientific article

Calcium-Mediated Control of S100 Proteins: Allosteric Communication via an Agitator/Signal Blocking Mechanism

scientific article

Calcium-dependent and -independent interactions of the S100 protein family.

scientific article

Calcium-induced peptide association to form an intact protein domain: 1H NMR structural evidence

scientific article published on 01 July 1990

Characterization of the dehydratase WcbK and the reductase WcaG involved in GDP-6-deoxy-manno-heptose biosynthesis in Campylobacter jejuni ⬇️

scientific article published on October 15, 2011

Comparison of Predicted Epimerases and Reductases of the Campylobacter jejuni d-altro- and l-gluco-Heptose Synthesis Pathways ⬇️

scientific article published on May 20, 2013

Conserved Region 3 of Human Papillomavirus 16 E7 Contributes to Deregulation of the Retinoblastoma Tumor Suppressor ⬇️

scientific article published on September 26, 2012

Cytochrome c as a Peroxidase: Activation of the Precatalytic Native State by H2O2-Induced Covalent Modifications.

scientific article

Differential interaction of the E3 ligase parkin with the proteasomal subunit S5a and the endocytic protein Eps15.

scientific article published on 29 October 2009

Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.

scientific article

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.

scientific article published on 7 August 2015

Elucidating the formation of 6-deoxyheptose: biochemical characterization of the GDP-D-glycero-d-manno-heptose C6 dehydratase, DmhA, and its associated C4 reductase, DmhB.

scientific article published on August 2009

Folding kinetics of the S100A11 protein dimer studied by time-resolved electrospray mass spectrometry and pulsed hydrogen-deuterium exchange.

scientific article

Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping.

scientific article published on 4 May 2016

Identification of a dimeric intermediate in the unfolding pathway for the calcium-binding protein S100B.

scientific article published on 6 August 2008

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

scientific article published in April 2009

Identification of calcium-independent and calcium-enhanced binding between S100B and the dopamine D2 receptor

scientific article published on 30 September 2011

Identification of regions responsible for the open conformation of S100A10 using chimaeric S100A11-S100A10 proteins.

scientific article published on February 2011

Impact of autosomal recessive juvenile Parkinson's disease mutations on the structure and interactions of the parkin ubiquitin-like domain.

scientific article published on 9 March 2011

Insights into S100 target specificity examined by a new interaction between S100A11 and annexin A2

scientific article published on 01 December 2006

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity

scientific article published on 17 April 2017

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

scientific article

Programmed ubiquitin acetylation using genetic code expansion reveals altered ubiquitination patterns

scientific article published on 02 December 2019

RBR E3 ubiquitin ligases: new structures, new insights, new questions

scientific article

RBR Ubiquitin Transfer: Not Simply an "Open" and "Closed" Case?

scientific article published on 01 June 2017

S100-annexin complexes--structural insights.

scientific article published on 13 September 2008

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase ⬇️

scientific article published on March 20, 2012

Solution and solid state conformation of the human EGF receptor transmembrane region ⬇️

scientific article published on May 28, 1998

Solution structure of the E3 ligase HOIL‐1 Ubl domain ⬇️

scientific article published on May 24, 2012

Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly.

scientific article

Structural Influence of Calcium on the Heme Cavity of Cationic Peanut Peroxidase as Determined by 1H-NMR Spectroscopy ⬇️

scientific article published on September 15, 1995

Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspG

scientific article

Structural influence of cation binding to recombinant human brain S100b: evidence for calcium-induced exposure of a hydrophobic surface.

scientific article published in July 1996

Structure of an asymmetric ternary protein complex provides insight for membrane interaction

scientific article

Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation

scientific article published on 22 December 2016

Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase

scientific article

Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease

scientific article

Suramin inhibits cullin-RING E3 ubiquitin ligases.

scientific article published on 21 March 2016

Switching on ubiquitylation by phosphorylating a ubiquitous activator

scientific article published on 01 June 2014

Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation

scientific article published on 16 November 2018

Systematic Analysis of the Amino Acid Residues of Human Papillomavirus Type 16 E7 Conserved Region 3 Involved in Dimerization and Transformation ⬇️

scientific article published on July 20, 2011

Temporal development of protein structure during S100A11 folding and dimerization probed by oxidative labeling and mass spectrometry.

scientific article

The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis

scientific article published on 23 March 2015

The S100A10-Annexin A2 Complex Provides a Novel Asymmetric Platform for Membrane Repair ⬇️

scientific article published on September 26, 2011

The Zn2+ and Ca2+ -binding S100B and S100A1 proteins: beyond the myths

scientific article published on 06 February 2020

The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation

scientific article published on 08 July 2019

Ubiquitin manipulation by an E2 conjugating enzyme using a novel covalent intermediate.

scientific article published on 12 July 2005

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