Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Francesca Cutruzzola'

A myoglobin mutant designed to mimic the oxygen-avid Ascaris suum hemoglobin: elucidation of the distal hydrogen bonding network by solution NMR

scientific article

A new folding intermediate of apomyoglobin from Aplysia limacina: stepwise formation of a molten globule11Edited by P. E. Wright

scientific article published on 01 April 2000

A new point mutation of the prion protein gene in Creutzfeldt-Jakob disease.

scientific article published on December 1993

A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa

scientific article published on 08 September 2018

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

scientific article

An Obligatory Intermediate in the Folding Pathway of Cytochromec552fromHydrogenobacter thermophilus

scientific article published in Journal of Biological Chemistry

Bacterial nitric oxide synthesis

scientific article published on 01 May 1999

Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms.

scientific article

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG

scientific article

Construction and characterization of a chimeric myoglobin.

scientific article

Control and recognition of anionic ligands in myoglobin

scientific article published on 01 May 1991

Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1nitrite reductase with oxygen

scientific article published on 11 September 2006

Cytochrome c(551) as a model system for protein folding.

scientific article published in January 2003

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

scientific article published on 26 November 2020

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.

scientific article published on 13 August 2016

Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes

scientific article published on 04 July 2018

Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases

scientific article published in January 2017

Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.

scientific article published on 10 July 2014

Does picosecond protein dynamics have survival value?

article

Does the reduction of c heme trigger the conformational change of crystalline nitrite reductase?

scientific article

Domain swing upon His to Ala mutation in nitrite reductase of Pseudomonas aeruginosa

scientific article

Dynamic Hydrogen-Bonding Network in the Distal Pocket of the Nitrosyl Complex of Pseudomonas aeruginosa cd1Nitrite Reductase

scientific article published on 10 February 2011

Engineering Ascaris hemoglobin oxygen affinity in sperm whale myoglobin: role of tyrosine B10

scientific article published on 01 September 1994

Engineering His(E7) affects the control of heme reactivity in Aplysia limacina myoglobin

scientific article

Equilibrium unfolding of a small bacterial cytochrome, cytochrome c 551 from Pseudomonas aeruginosa

scientific article published on 01 April 1998

Expression and characterization of Pseudomonas aeruginosa cytochrome c-551 and two site-directed mutants: role of tryptophan 56 in the modulation of redox properties.

scientific article published on February 1997

Expression of Pseudomonas aeruginosa nitrite reductase in Pseudomonas putida and characterization of the recombinant protein ⬇️

scientific article published on July 15, 1992

Fast Dissociation of Nitric Oxide from FerrousPseudomonas aeruginosacd1Nitrite Reductase

scientific article published in Journal of Biological Chemistry

Folding mechanism of Pseudomonas aeruginosa cytochrome c 551 : role of electrostatic interactions on the hydrophobic collapse and transition state properties 1 1Edited by P. E. Wright

scientific article published on 01 June 1999

Formate binding to ferric wild type and mutant myoglobins thermodynamic and X-ray crystallographic study

scientific article published on 01 January 1995

Glucose Metabolism in the Progression of Prostate Cancer

scientific article published on 21 February 2017

Haemoglobin engineering. For fun and money.

scientific article published on May 1995

Heme d1 nitrosyl complex of cd1 nitrite reductase studied by high-field-pulse electron paramagnetic resonance spectroscopy.

scientific article

Histidine and not tyrosine is required for the peroxide-induced formation of haem to protein cross-linked myoglobin.

scientific article published on August 2007

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

scientific article

Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties

scientific article published on 07 December 2018

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD

scientific article published on 28 September 2015

In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed

scientific article (publication date: May 2011)

Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa

scientific article published on 07 September 2018

Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin

scientific article

Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.

scientific article published on 23 October 2012

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain

scientific article (publication date: 2013)

Isolation and characterization of the d1 domain of Pseudomonas aeruginosa nitrite reductase

scientific article published on 01 May 1996

Mutagenesis of nitrite reductase from Pseudomonas aeruginosa : tyrosine-10 in the c heme domain is not involved in catalysis 1

scientific article published on 01 July 1997

N-oxide sensing and denitrification: the DNR transcription factors.

scientific article

N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.

scientific article published in February 2005

N-terminal arm exchange is observed in the 2.15 Å crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa ⬇️

scientific article published on September 15, 1997

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease.

scientific article published on 16 March 2012

Nitrite controls the release of nitric oxide in Pseudomonas aeruginosa cd1 nitrite reductase.

scientific article published on 20 September 2007

Nitrite reduction: a ubiquitous function from a pre-aerobic past.

scientific article published on August 2009

Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis

scientific article published on 10 August 2014

Novel genetic tools to tackle c-di-GMP-dependent signalling in Pseudomonas aeruginosa.

scientific article published on 23 October 2015

Observation of fast release of NO from ferrousd1haem allows formulation of a unified reaction mechanism for cytochromecd1nitrite reductases

scientific article published on 01 April 2011

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases ⬇️

scientific article published on December 5, 2011

Origin and Impact of Nitric Oxide in Pseudomonas aeruginosa Biofilms

scientific article

Parallel pathways in cytochrome c(551) folding.

scientific article

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy ⬇️

scientific article published on January 28, 2013

Pseudomonas aeruginosa cytochrome C551: probing the role of the hydrophobic patch in electron transfer

scientific article published on 01 February 2002

Pseudomonas aeruginosa nitrite reductase (or cytochrome oxidase): an overview.

scientific article published on January 1994

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis

scientific article published on 15 September 2017

Reaction of Aplysia limacina metmyoglobin with hydrogen peroxide

scientific article published on 17 January 2007

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

scientific article

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

scientific article published on 10 February 2015

Selective oxidation of methionyl residues in the human recombinant secretory leukocyte proteinase inhibitor. Effect on the inhibitor binding properties

scientific article published on 01 March 1994

Serine and glycine metabolism in cancer

scientific article

Solvent accessibility in the distal heme pocket of the nitrosyl d(1)-heme complex of Pseudomonas stutzeri cd(1) nitrite reductase

scientific article published on 02 November 2012

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site

scientific article published on 17 February 2015

Structural determinants of fluoride and formate binding to hemoglobin and myoglobin: crystallographic and 1H-NMR relaxometric study.

scientific article published on January 1996

The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms

scientific article published on 01 January 2011

The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells

scientific article published on 07 August 2018

The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase

scientific article published on 01 January 2011

The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.

scientific article published on 14 April 2013

The nitrite reductase gene of Pseudomonas aeruginosa: effect of growth conditions on the expression and construction of a mutant by gene disruption

scientific article published on 01 May 1993

The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.

scientific article published on 10 January 2014

The role of cavities in protein dynamics: Crystal structure of a photolytic intermediate of a mutant myoglobin

scientific article

The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli.

scientific article

Tyrosine as a redox-active center in electron transfer to ferryl heme in globins.

scientific article published on 22 August 2007

Unfolding of apomyoglobin from Aplysia limacina : the effect of salt and ph on the cooperativity of folding 1 1Edited by P. E. Wright

article

Unusual heme binding properties of the dissimilative nitrate respiration regulator, a bacterial nitric oxide sensor.

scientific article published on 27 April 2012

p73 keeps metabolic control in balance

scientific article published on 22 November 2013

Paulina is supported by:

About Paulina

Help