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List of works by Serena Rinaldo

A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa

scientific article published on 08 September 2018

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

scientific article

AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach

scientific article published in 2024

Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms.

scientific article

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG

scientific article

Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1nitrite reductase with oxygen

scientific article published on 11 September 2006

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

scientific article published on 26 November 2020

Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes

scientific article published on 04 July 2018

Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases

scientific article published in January 2017

Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.

scientific article published on 10 July 2014

Dynamic Hydrogen-Bonding Network in the Distal Pocket of the Nitrosyl Complex of Pseudomonas aeruginosa cd1Nitrite Reductase

scientific article published on 10 February 2011

Fast Dissociation of Nitric Oxide from FerrousPseudomonas aeruginosacd1Nitrite Reductase

scientific article published in Journal of Biological Chemistry

Fractalkine Modulates Microglia Metabolism in Brain Ischemia

scientific article published on 13 September 2019

Glucose Metabolism in the Progression of Prostate Cancer

scientific article published on 21 February 2017

Heme d1 nitrosyl complex of cd1 nitrite reductase studied by high-field-pulse electron paramagnetic resonance spectroscopy.

scientific article

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

scientific article

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

scientific article

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD

scientific article published on 28 September 2015

In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed

scientific article (publication date: May 2011)

Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa

scientific article published on 07 September 2018

Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding.

scientific article published on 23 October 2012

Intramolecular electron transfer in Pseudomonas aeruginosa cd(1) nitrite reductase: thermodynamics and kinetics

scientific article

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain

scientific article (publication date: 2013)

Linking Infection and Prostate Cancer Progression: Toll-like Receptor3 Stimulation Rewires Glucose Metabolism in Prostate Cells

scientific article published on 01 October 2019

N-oxide sensing and denitrification: the DNR transcription factors.

scientific article

N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.

scientific article published in February 2005

NO production by Pseudomonas aeruginosa cd1 nitrite reductase

scientific journal article

NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR

scientific article

New insights into the activity of Pseudomonas aeruginosa cd1 nitrite reductase

scientific article published on December 2008

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease.

scientific article published on 16 March 2012

Nitrite controls the release of nitric oxide in Pseudomonas aeruginosa cd1 nitrite reductase.

scientific article published on 20 September 2007

Nitrite reduction: a ubiquitous function from a pre-aerobic past.

scientific article published on August 2009

Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis

scientific article published on 10 August 2014

Novel genetic tools to tackle c-di-GMP-dependent signalling in Pseudomonas aeruginosa.

scientific article published on 23 October 2015

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas

scientific article published in 2022

Observation of fast release of NO from ferrousd1haem allows formulation of a unified reaction mechanism for cytochromecd1nitrite reductases

scientific article published on 01 April 2011

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy ⬇️

scientific article published on January 28, 2013

Reaction of Aplysia limacina metmyoglobin with hydrogen peroxide

scientific article published on 17 January 2007

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

scientific article

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

scientific article published on 10 February 2015

Solvent accessibility in the distal heme pocket of the nitrosyl d(1)-heme complex of Pseudomonas stutzeri cd(1) nitrite reductase

scientific article published on 02 November 2012

Structural and functional investigation of the Small Ribosomal Subunit Biogenesis GTPase A (RsgA) from Pseudomonas aeruginosa

scientific article published on 02 July 2019

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site

scientific article published on 17 February 2015

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts

scientific article published on 06 January 2021

Synthesis of Triazole-Linked Analogues of c-di-GMP and Their Interactions with Diguanylate Cyclase.

scientific article published on October 2015

The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms

scientific article published on 01 January 2011

The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells

scientific article published on 07 August 2018

The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase

scientific article published on 01 January 2011

The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.

scientific article published on 14 April 2013

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism

scientific article published on 01 May 2019

The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.

scientific article published on 10 January 2014

The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli.

scientific article

Unusual heme binding properties of the dissimilative nitrate respiration regulator, a bacterial nitric oxide sensor.

scientific article published on 27 April 2012

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