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List of works by Fiona Wightman

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

scientific article (publication date: October 2014)

Altering cell death pathways as an approach to cure HIV infection

scientific article published on 11 July 2013

Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy

scientific article

CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency

scientific article published on 19 September 2007

Cancer therapies in HIV cure research

scientific article published on 7 September 2016

Coinfection of hepatic cell lines with human immunodeficiency virus and hepatitis B virus leads to an increase in intracellular hepatitis B surface antigen

scientific article

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

scientific article published on 31 January 2013

Comparison of sequence analysis and a novel discriminatory real-time PCR assay for detection and quantification of Lamivudine-resistant hepatitis B virus strains.

scientific article

Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma

scientific article published in February 2015

Enhanced replicative capacity and pathogenicity of HIV-1 isolated from individuals infected with drug-resistant virus and declining CD4+ T-cell counts

scientific article

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

scientific article

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.

scientific article

Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.

scientific article

HDAC inhibitors in HIV.

scientific article

HIV Reservoirs and Strategies for Eradication ⬇️

scientific article published on March 1, 2012

Highly reproducible transient transfections for the study of hepatitis B virus replication based on an internal GFP reporter system

scientific article published on October 2004

No adverse safety or virological changes 2 years following vorinostat in HIV-infected individuals on antiretroviral therapy

scientific article published on 15 March 2017

No increase in hepatitis B virus (HBV)-specific CD8+ T cells in patients with HIV-1-HBV coinfections following HBV-active highly active antiretroviral therapy

scientific article

Reduced hepatitis B virus (HBV)-specific CD4+ T-cell responses in human immunodeficiency virus type 1-HBV-coinfected individuals receiving HBV-active antiretroviral therapy

scientific article published in March 2005

Severe hepatitis and prolonged hepatitis B virus-specific CD8 T-cell response after selection of hepatitis B virus YMDD variant in an HIV/hepatitis B virus-co-infected patient

scientific article

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.

scientific article

The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection.

scientific article published in November 2007

Understanding Factors That Modulate the Establishment of HIV Latency in Resting CD4+ T-Cells In Vitro

scientific article

Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection.

scientific article

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