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List of works by Hans Dieter Nischalke

A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease

scientific article

A farnesoid X receptor polymorphism predisposes to spontaneous bacterial peritonitis.

scientific article published on 30 July 2014

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

scientific article published on 19 October 2015

A variant in the nuclear dot protein 52kDa gene increases the risk for spontaneous bacterial peritonitis in patients with alcoholic liver cirrhosis.

scientific article published on 28 September 2015

Altered expression of TGF-beta receptors in hepatocellular carcinoma--effects of a constitutively active TGF-beta type I receptor mutant

scientific article

An effective interferon-gamma-mediated inhibition of hepatitis C virus replication by natural killer cells is associated with spontaneous clearance of acute hepatitis C in human immunodeficiency virus-positive patients.

scientific article published on 21 January 2014

Antibiotic resistance in healthcare-related and nosocomial spontaneous bacterial peritonitis.

scientific article

Between Scylla and Charybdis: the role of the human immune system in the pathogenesis of hepatitis C.

scientific article

Binding of HCV E2 to CD81 induces RANTES secretion and internalization of CC chemokine receptor 5.

scientific article published on November 2004

CD27(+)CD56Bright natural killer cells may be involved in spontaneous clearance of acute hepatitis C in HIV-positive patients.

scientific article published on August 2014

Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy

scientific article

Corrigendum: PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease

scientific article published on 01 July 2015

Decreased prevalence of Helicobacter pylori infection in HIV patients with AIDS defining diseases

scientific article published on 01 January 2002

Detection of IGF2BP3, HOXB7, and NEK2 mRNA expression in brush cytology specimens as a new diagnostic tool in patients with biliary strictures

scientific article

Detection of human aspartyl (asparaginyl) beta-hydroxylase and homeobox B7 mRNA in brush cytology specimens from patients with bile duct cancer

scientific article (publication date: June 2006)

Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients.

scientific article published on October 2007

Genetic polymorphisms associated with fatty liver disease and fibrosis in HIV positive patients receiving combined antiretroviral therapy (cART).

scientific article

Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis

scientific article published on 13 March 2018

Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIV-positive patients with acute and chronic hepatitis C.

scientific article

HIV-1 infection leads to increased HLA-E expression resulting in impaired function of natural killer cells

scientific article published on 01 January 2005

Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis.

scientific article published on 4 October 2010

Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C.

scientific article published in October 2006

Hepatitis C virus-derived lipopeptides differentially induce epitope-specific immune responses in vitro.

scientific article published on 8 January 2004

Hypoxia impairs anti-viral activity of natural killer (NK) cells but has little effect on anti-fibrotic NK cell functions in hepatitis C virus infection

scientific article published on 19 August 2015

IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C.

scientific article published on September 2016

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

scientific article

Impaired CD4⁺ T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients.

scientific article published on 9 May 2013

Increased peripheral CD4+ regulatory T cells persist after successful direct-acting antiviral treatment of chronic hepatitis C.

scientific article

Induction of interleukin-6 by hepatitis C virus core protein in hepatitis C-associated mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma.

scientific article published in August 2006

Influence of genetic variations in the SOD1 gene on the development of ascites and spontaneous bacterial peritonitis in decompensated liver cirrhosis

scientific article published on 11 April 2017

Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent

scientific article published on 18 November 2013

Interferon-lambda serum levels in hepatitis C.

scientific article published on 23 October 2010

Intrahepatic IL-8 producing Foxp3⁺CD4⁺ regulatory T cells and fibrogenesis in chronic hepatitis C.

scientific article published on 23 April 2013

Intrahepatic mRNA levels of interferon gamma and tumor necrosis factor alpha and response to antiviral treatment of chronic hepatitis C

scientific article published on July 1, 2001

Low ascitic fluid protein does not indicate an increased risk for spontaneous bacterial peritonitis in current cohorts

scientific article published on 24 May 2015

Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis.

scientific article published on 31 August 2012

Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma

scientific article

PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.

scientific article published on 12 May 2015

Progression of liver fibrosis in HIV/HCV genotype 1 co-infected patients is related to the T allele of the rs12979860 polymorphism of the IL28B gene.

scientific article

Rapid determination of the Delta32 deletion in the human CC-chemokine receptor 5 (CCR5) gene without DNA extraction by lightcycler real-time polymerase chain reaction

scientific article

Reduced CC chemokine receptor (CCR) 1 and CCR5 surface expression on peripheral blood T lymphocytes from patients with chronic hepatitis C infection

scientific article published on 20 May 2002

Regulation of NK cell trafficking by CD81.

scientific article

Relative Ascites Polymorphonuclear Cell Count Indicates Bacterascites and Risk of Spontaneous Bacterial Peritonitis.

scientific article published on 09 June 2017

Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C.

scientific article

Semi-quantification of human C-C chemokine mRNAs with reverse transcription/real-time PCR using multi-specific standards

scientific article published on 01 July 2000

Spontaneous bacterial peritonitis: The clinical challenge of a leaky gut and a cirrhotic liver

scientific article

TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients.

scientific article

The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C

scientific article

The HLA-E(R)/HLA-E(R) genotype affects the natural course of hepatitis C virus (HCV) infection and is associated with HLA-E-restricted recognition of an HCV-derived peptide by interferon-gamma-secreting human CD8(+) T cells.

scientific article published on November 2009

The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu

scientific article published on 21 October 2019

The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis

scientific article

The cytotoxic lymphocyte antigen 4 polymorphisms affect response to hepatitis C virus-specific therapy in HIV(+) patients with acute and chronic hepatitis C virus co-infection.

scientific article published in August 2010

The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation

article

The ratio of calprotectin to total protein as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

scientific article

The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS

scientific article published on 01 April 2003

The tandem-repeat polymorphism of the DC-SIGNR gene in HCV infection.

scientific article published in January 2006

The transforming growth factor-beta high-producer genotype is associated with response to hepatitis C virus-specific therapy in HIV-positive patients with acute hepatitis C.

scientific article published in July 2008

Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis

scientific article published on 26 February 2011

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