List of works - Clement Opoku-Temeng

3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.

scientific article published on 17 April 2018

Agents that inhibit bacterial biofilm formation.

scientific article published on January 2015

Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase.

scientific article

Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines.

scientific article published on 11 May 2017

Biofilm formation mechanisms and targets for developing antibiofilm agents.

scientific article published on January 2015

Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules.

scientific article published on 24 June 2016

Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines.

scientific article published on 13 February 2018

Fluorescent 2-Aminopurine c-di-GMP and GpG Analogs as PDE Probes

scientific article published on January 2017

Fluorescent analogs of cyclic and linear dinucleotides as phosphodiesterase and oligoribonuclease activity probes

article

Front Cover: Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase (ChemMedChem 12/2018)

scholarly article by Elizabeth A. Larocque et al published 20 June 2018 in ChemMedChem

Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators

scientific article published on 01 February 2015

Hydroxybenzylidene-indolinones, c-di-AMP synthase inhibitors, have antibacterial and anti-biofilm activities and also re-sensitize resistant bacteria to methicillin and vancomycin

article

Inhibition of c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative

article

Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols

scientific article published on 6 May 2016

N -(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria

scientific article published on 15 June 2018

Potent inhibition of cyclic diadenylate monophosphate cyclase by the antiparasitic drug, suramin

scientific article published on 01 March 2016

Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels

scientific article published on 21 March 2018

Targeting c-di-GMP Signaling, Biofilm Formation, and Bacterial Motility with Small Molecules.

scientific article published on January 2017

List of works by Clement Opoku-Temeng

3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.

Agents that inhibit bacterial biofilm formation.

Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase.

Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines.

Biofilm formation mechanisms and targets for developing antibiofilm agents.

Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules.

Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines.

Fluorescent 2-Aminopurine c-di-GMP and GpG Analogs as PDE Probes

Fluorescent analogs of cyclic and linear dinucleotides as phosphodiesterase and oligoribonuclease activity probes

Front Cover: Alkynylnicotinamide-Based Compounds as ABL1 Inhibitors with Potent Activities against Drug-Resistant CML Harboring ABL1(T315I) Mutant Kinase (ChemMedChem 12/2018)

Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators

Hydroxybenzylidene-indolinones, c-di-AMP synthase inhibitors, have antibacterial and anti-biofilm activities and also re-sensitize resistant bacteria to methicillin and vancomycin

Inhibition of c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative

Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols

N -(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria

Potent inhibition of cyclic diadenylate monophosphate cyclase by the antiparasitic drug, suramin

Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels

Targeting c-di-GMP Signaling, Biofilm Formation, and Bacterial Motility with Small Molecules.

Tetrahydro-3H-pyrazolo[4,3-a]phenanthridine-based CDK inhibitor