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List of works by Dale Moulding

A congenital activating mutant of WASp causes altered plasma membrane topography and adhesion under flow in lymphocytes

scientific article

Actin cytoskeletal defects in immunodeficiency

scientific article

Activation of human neutrophils by soluble immune complexes: role of Fc gamma RII and Fc gamma RIIIb in stimulation of the respiratory burst and elevation of intracellular Ca2+.

scientific article

Activation of podocyte Notch mediates early Wt1 glomerulopathy.

scientific article published on 2 February 2018

Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications.

scientific article published in September 2004

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

scientific article published in September 2000

Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1

scientific article

BCL-2 family expression in human neutrophils during delayed and accelerated apoptosis.

scientific article published in November 2001

Biomechanical coupling facilitates spinal neural tube closure in mouse embryos

scientific article

Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures

scientific article published on 08 October 2011

Cellular control of cortical actin nucleation

scientific article

Design of a Novel Two-Component Hybrid Dermal Scaffold for the Treatment of Pressure Sores.

scientific article published on 12 September 2017

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

scientific article

E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner

scientific article published on 05 June 2017

Effects of staphylococcal enterotoxins on human neutrophil functions and apoptosis

scientific article

Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome

scientific article published on 11 May 2022

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors.

scientific article published on 11 September 2017

Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity

scientific article published on 12 September 2012

Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion

scientific article (publication date: 2016)

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.

scientific article

In vitro effects of GM-CSF on mature peripheral blood neutrophils

scientific article published on 01 June 1998

In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins

scientific article published on 01 July 2000

Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival

scientific article published on 01 October 1998

Modulation of neutrophil apoptosis by pharmacological agents

scientific article published on 01 August 1996

Molecular control of neutrophil apoptosis.

scientific article

Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

scientific article published in Nature Communications

Phosphorylation of WASp is a key regulator of activity and stability in vivo

scientific article published on September 2009

Regulation of neutrophil FcgammaRIIIb (CD16) surface expression following delayed apoptosis in response to GM-CSF and sodium butyrate

scientific article published on 01 June 1999

Regulation of neutrophil apoptosis by sodium butyrate

scientific article published on 01 December 1996

Severe autoinflammatory disease caused by mutation in a gene controlling actin cytoskeletal dynamics and cure with allogeneic haematopoetic stem cell transplantation.

scientific article

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.

scientific article

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

scientific article published on 6 June 2019

The cytoplasm of living cells behaves as a poroelastic material

scientific article published on 6 January 2013

The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

scientific article published in 2022

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

scientific article published on 27 August 2007

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

scientific article