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List of works by Ryszard Kierzek

A Conserved Secondary Structural Element in the Coding Region of the Influenza A Virus Nucleoprotein (NP) mRNA Is Important for the Regulation of Viral Proliferation

scientific article published on 21 October 2015

A Disease-Causing Intronic Point Mutation C19G Alters Tau Exon 10 Splicing via RNA Secondary Structure Rearrangement

scientific article published on 07 March 2019

A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides

scientific article published on 6 November 2015

A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2'-O-methyl-2,6-diaminopurine and LNA-2,6-diaminopurine ribosides on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes

scientific article published on 12 June 2007

A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme.

scientific article published in January 2007

A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo

scientific article

A locked derivative of 8-aza-7-deazaadenosine

scientific article

Antibodies specific for branched ribonucleic acids.

scientific article

Antisense Oligonucleotides Targeting Influenza A Segment 8 Genomic RNA Inhibit Viral Replication

scientific article published on 27 July 2016

Association of 2'-5' oligoribonucleotides ⬇️

scientific article published on April 11, 1992

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases

scientific article

Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning

scientific article

Binding of guanosine and 3' splice site analogues to a group I ribozyme: interactions with functional groups of guanosine and with additional nucleotides

scientific article published on 01 May 1993

Case of Plasmodium knowlesi Malaria in Poland Linked to Travel in Southeast Asia

scientific article published on 01 September 2019

Chemical synthesis and binding activity of the trypanosomatid cap-4 structure

scientific article

Chemical synthesis of LNA-2-thiouridine and its influence on stability and selectivity of oligonucleotide binding to RNA.

scientific article

Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain

scientific article published on September 2010

Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair

scientific article published on 07 November 2019

Conscious uncoupling of riboswitch functions

scientific article published on 28 February 2020

Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin

scientific article published on April 10, 1992

Contributions of stacking, preorganization, and hydrogen bonding to the thermodynamic stability of duplexes between RNA and 2'-O-methyl RNA with locked nucleic acids

scientific article

Correction: A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides

scientific article published on 19 September 2016

Correction: The 3′ Splice Site of Influenza A Segment 7 mRNA Can Exist in Two Conformations: A Pseudoknot and a Hairpin.

scientific article published on 18 September 2012

Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome

scientific article

Crystallographic characterization of CCG repeats

scientific article

Distinctive structural motifs of RNA G-quadruplexes composed of AGG, CGG and UGG trinucleotide repeats

scientific article

Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods

scientific article published on 01 November 1992

Effects of GA mismatches on the structure and thermodynamics of RNA internal loops

scientific article published on 01 September 1990

Energetics of internal GU mismatches in ribooligonucleotide helixes

scientific article published on 01 September 1986

Exploring the energy landscape of a small RNA hairpin

scientific article published on 01 February 2006

Facilitating RNA structure prediction with microarrays

scientific article

Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate

scientific article

Free energy contributions of G.U and other terminal mismatches to helix stability

scientific article published on 01 June 1986

Guanosine binds to the Tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging pro-Sp phosphoryl oxygen at the cleavage site are required for productive docking

scientific article published on 01 October 1997

High-resolution crystal structure of Z-DNA in complex with Cr(3+) cations

scientific article

Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine.

scientific article published on 9 September 2015

Hydrolysis of oligoribonucleotides: influence of sequence and length ⬇️

scientific article published on October 11, 1992

Improved free-energy parameters for predictions of RNA duplex stability

scientific article (publication date: December 1986)

Improved parameters for prediction of RNA structure

scientific article published on 01 January 1987

Influence of mismatched and bulged nucleotides on SNP-preferential RNase H cleavage of RNA-antisense gapmer heteroduplexes.

scientific article published on 2 October 2017

Influenza virus segment 5 (+)RNA - secondary structure and new targets for antiviral strategies

scientific article published on 8 November 2017

Interplay of LNA and 2'-O-methyl RNA in the structure and thermodynamics of RNA hybrid systems: a molecular dynamics study using the revised AMBER force field and comparison with experimental results

scientific article published on 30 September 2014

Isoenergetic microarrays to study the structure and interactions of DsrA and OxyS RNAs in two- and three-component complexes

scientific article published on 15 August 2011

Isoenergetic penta- and hexanucleotide microarray probing and chemical mapping provide a secondary structure model for an RNA element orchestrating R2 retrotransposon protein function

scientific article

LNA-modified primers drastically improve hybridization to target RNA and reverse transcription.

scientific article

Metal-promoted synthesis, characterization, crystal structure and RNA cleavage ability of 2,6-diacetylpyridine bis(2-aminobenzoylhydrazone) lanthanide complexes.

scientific article

Microarrays for identifying binding sites and probing structure of RNAs

scientific article

Modified RNA triplexes: Thermodynamics, structure and biological potential

scientific article published in Scientific Reports

Molecular Dynamics Correctly Models the Unusual Major Conformation of the GAGU RNA Internal Loop and with NMR Reveals an Unusual Minor Conformation

scientific article published on 6 February 2018

Nearest neighbor parameters for Watson-Crick complementary heteroduplexes formed between 2'-O-methyl RNA and RNA oligonucleotides

scientific article published on 26 July 2006

Nearest-neighbor parameters for G.U mismatches: [formula; see text] is destabilizing in the contexts [formula; see text] and [formula; see text] but stabilizing in [formula; see text]

scientific article published on 01 November 1991

Nonenzymatic cleavage of oligoribonucleotides.

scientific article

Nonenzymatic hydrolysis of oligoribonucleotides.

scientific article published in October 1992

Novel Conformation of an RNA Structural Switch

scientific article

Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2)

scientific article

Optimization of an AMBER force field for the artificial nucleic acid, LNA, and benchmarking with NMR of L(CAAU).

scientific article published on 24 January 2014

Parallel-stranded DNA and RNA duplexes - structural features and potential applications.

scientific article

Photoaddition of 5-Bromouracil to Uracil in Oligonucleotides Leading to 5,5′-Bipyrimidine-Type Adducts: Mechanism of the Photoreaction

scientific article published on 05 December 2012

RNA Internal Loops with Tandem AG Pairs: The Structure of the 5′G AG U/3′U GA G Loop Can Be Dramatically Different from Others, Including 5′A AG U/3′U GA A

scientific article

RNA Secondary Structure Motifs of the Influenza A Virus as Targets for siRNA-Mediated RNA Interference

scientific article published on 24 December 2019

RNA Secondary Structure as a First Step for Rational Design of the Oligonucleotides towards Inhibition of Influenza A Virus Replication

scientific article published on 07 November 2020

RNA Secondary Structure-Based Design of Antisense Peptide Nucleic Acids for Modulating Disease-Associated Aberrant Tau Pre-mRNA Alternative Splicing

scientific article published on 20 August 2019

Recognition of RNA duplexes by chemically modified triplex-forming oligonucleotides

scientific article

Restricting the conformational heterogeneity of RNA by specific incorporation of 8-bromoguanosine

scientific article published in March 2003

Revision of AMBER Torsional Parameters for RNA Improves Free Energy Predictions for Tetramer Duplexes with GC and iGiC Base Pairs

scientific article published on December 2011

Role of unsatisfied hydrogen bond acceptors in RNA energetics and specificity

scientific article published on 01 April 2010

Secondary structure model of the naked segment 7 influenza A virus genomic RNA.

scientific article published on 30 September 2016

Secondary structure of a conserved domain in the intron of influenza A NS1 mRNA

scientific article (publication date: 2013)

Secondary structure of the segment 5 genomic RNA of influenza A virus and its application for designing antisense oligonucleotides

scientific article published on 07 March 2019

Secondary structures for 5' regions of R2 retrotransposon RNAs reveal a novel conserved pseudoknot and regions that evolve under different constraints

scientific article

Self-Folding of Naked Segment 8 Genomic RNA of Influenza A Virus

scientific article

Sequence dependence for the energetics of dangling ends and terminal base pairs in ribonucleic acid

scientific article published on 01 July 1987

Sequence dependence for the energetics of terminal mismatches in ribooligonucleotides

scientific article published on 01 July 1987

Small Molecule Rescue and Glycosidic Conformational Analysis of the Twister Ribozyme

scientific article published on 19 November 2019

Solid-supported synthesis of 5'-mRNA CAP-4 from Trypanosomatids

scientific article published in January 2007

Spectroscopic study of fluorescent probes based on G-quadruplex oligonucleotides labeled with ethynylpyrenyldeoxyuridine.

scientific article published on 17 July 2017

Stabilities of consecutive A.C, C.C, G.G, U.C, and U.U mismatches in RNA internal loops: Evidence for stable hydrogen-bonded U.U and C.C.+ pairs

scientific article published on 01 August 1991

Stability and structure of RNA duplexes containing isoguanosine and isocytidine

scientific article

Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids

scientific article published on 01 June 1986

Stabilization of RNA hairpins using non-nucleotide linkers and circularization

scientific article

Stacking Effects on Local Structure in RNA:  Changes in the Structure of Tandem GA Pairs when Flanking GC Pairs Are Replaced by isoG−isoC Pairs †

scientific article

Stacking in RNA: NMR of Four Tetramers Benchmark Molecular Dynamics

scientific article (publication date: 9 June 2015)

Structural Aspects of the Antiparallel and Parallel Duplexes Formed by DNA, 2'-O-Methyl RNA and RNA Oligonucleotides

scientific article published on 18 November 2015

Structural characterization of a dimer of RNA duplexes composed of 8-bromoguanosine modified CGG trinucleotide repeats: a novel architecture of RNA quadruplexes

scientific article published on 6 January 2016

Structural determinants for alternative splicing regulation of the MAPT pre-mRNA

scientific article

Structural diversity of triplet repeat RNAs

scientific article published on 16 February 2010

Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy

scientific article

Structure determination of noncanonical RNA motifs guided by ¹H NMR chemical shifts

scientific article published on 02 March 2014

Structure of an RNA/DNA dodecamer corresponding to the HIV-1 polypurine tract at 1.6 Å resolution

scientific article

Studies on Transcriptional Incorporation of 5'-N-Triphosphates of 5'-Amino-5'-Deoxyribonucleosides

scientific article published in February 2016

Synthesis of Leishmania cap-4 intermediates, cap-2 and cap-3.

scientific article published in January 2007

Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine

scientific article published on September 2004

The 3′ Splice Site of Influenza A Segment 7 mRNA Can Exist in Two Conformations: A Pseudoknot and a Hairpin ⬇️

scientific article published on June 7, 2012

The chemical synthesis of oligoribonucleotides with selectively placed 2'-O-phosphates

scientific article published on 01 May 2000

The chemical synthesis of the anticodon loop of an eukaryotic initiator tRNA containing the hypermodified nucleoside N6-/N-threonylcarbonyl/-adenosine/t6A/1.

scientific article published on June 1978

The contribution of pseudouridine to stabilities and structure of RNAs

scientific article published on 24 December 2013

The influence of locked nucleic acid residues on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes

scientific article

The influence of various modified nucleotides placed as 3'-dangling end on thermal stability of RNA duplexes

scientific article published in June 2002

The nonenzymatic hydrolysis of oligoribonucleotides. VII. Structural elements affecting hydrolysis

scientific article published on 01 May 2000

The origin of the high stability of 3'-terminal uridine tetrads. The contributions of hydrogen bonding, stacking interactions and steric factors evaluated using modified oligonucleotide analogs

scientific article published on 23 September 2020

The regulation properties of RNA secondary structure in alternative splicing

scientific article published on 16 July 2019

The spontaneous rearrangement of 2,4-dinitrophenyl substituent in ribonucleosides under neutral conditions

scientific article published on September 2010

The synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines via post-synthetic modification of precursor oligomers

scientific article

The thermal stability of RNA duplexes containing modified base pairs placed at internal and terminal positions of the oligoribonucleotides

scientific article published in June 2002

The thermodynamic stability of RNA duplexes and hairpins containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines

scientific article

The thermodynamics of 3'-terminal pyrene and guanosine for the design of isoenergetic 2'-O-methyl-RNA-LNA chimeric oligonucleotide probes of RNA structure

scientific article published on 5 January 2008

Thermodynamic Features of Structural Motifs Formed by β-L-RNA

scientific article

Thermodynamic Stability of RNA Structures Formed by CNG Trinucleotide Repeats. Implication for Prediction of RNA Structure†

scientific article published in August 2005

Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides.

scientific article

Thermodynamic and structural contributions of the 6-thioguanosine residue to helical properties of RNA

scientific article published on 13 March 2019

Thermodynamic study of internal loops in oligoribonucleotides: symmetric loops are more stable than asymmetric loops.

scientific article published in July 1991

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative.

scientific article published on 30 December 2017

Thermodynamics of RNA-RNA duplexes with 2- or 4-thiouridines: implications for antisense design and targeting a group I intron.

scientific article

Thermodynamics of single mismatches in RNA duplexes

scientific article published on 01 October 1999

Thermodynamics of unpaired terminal nucleotides on short RNA helixes correlates with stacking at helix termini in larger RNAs.

scientific article published in July 1999

Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions

scientific article

Unlocked nucleic acids: implications of increased conformational flexibility for RNA/DNA triplex formation

scientific article published on 01 December 2014

Unraveling the structural basis for the exceptional stability of RNA G-quadruplexes capped by a uridine tetrad at the 3' terminus

scientific article published on 19 October 2018

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