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List of works by Salvatore Guarini

ACTH-(1-24) restores blood pressure in acute hypovolaemia and haemorrhagic shock in humans

scientific article published on 01 January 1987

Absorption of heparin injected into various parts of the rat intestinal tract: a bile-dependent mechanism?

Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats

scientific article published in November 2005

Activation of the cholinergic anti-inflammatory pathway reduces NF-kappab activation, blunts TNF-alpha production, and protects againts splanchic artery occlusion shock

scientific article published on 01 May 2006

Adrenal-independent, anti-shock effect of ACTH-(1-24) in rats

scientific article published on 01 April 1986

Adrenocorticotropin counteracts the increase in free radical blood levels, detected by electron spin resonance spectrometry, in rats subjected to prolonged asphyxia.

scientific article

Adrenocorticotropin inhibits nitric oxide synthase II mRNA expression in rat macrophages

scientific article published on 01 January 2000

Adrenocorticotropin normalizes the blood levels of nitric oxide in hemorrhage-shocked rats

scientific article published on 01 October 1997

Adrenocorticotropin release is not involved in the nicotine-induced reversal of hemorrhagic shock in anesthetized rats

scientific article published on 01 January 1995

Adrenocorticotropin reversal of experimental hemorrhagic shock is antagonized by morphine

scientific article published on 01 October 1986

Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway.

scientific article published in August 2004

Adrenocorticotropin reverses vascular dysfunction and protects against splanchnic artery occlusion shock.

scientific article published on October 1999

Alpha-MSH and other ACTH fragments improve cardiovascular function and survival in experimental hemorrhagic shock

scientific article published on 01 October 1986

Anti-shock effect of ACTH-(1-24) in rats: comparison between intracerebroventricular and intravenous route of administration

scientific article published on 01 March 1987

Anti-shock effect of ACTH-(1-24): influence of subtotal hepatectomy.

scientific article

Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.

scientific article published on 27 October 2005

Broad therapeutic treatment window of [Nle(4), D-Phe(7)]alpha-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils.

scientific article published on 24 March 2006

Caerulein and cholecystokinin reverse experimental hemorrhagic shock

scientific article published on 01 July 1986

Cannabinoid CB(1) receptor blockade enhances the protective effect of melanocortins in hemorrhagic shock in the rat.

scientific article

Capsaicin prevents the adrenocorticotropin-induced improvement of cardiovascular function and survival in hemorrhage-shocked rats

scientific article published on 01 August 1992

Centrally acting leptin induces a resuscitating effect in haemorrhagic shock in rats

scientific article published on 29 March 2012

Characteristics of brain, heart ventricle and spleen capsule adrenoceptors in rats bled to hypovolemic shock and treated with ACTH-(1-24)

scientific article published on 01 December 1989

Cholecystokinin peptides and bombesin reverse hemorrhagic shock in rats

scientific article published on 01 December 1989

Circulatory and respiratory consequences of massive hemorrhage are reversed by protoveratrines

scientific article published on 01 July 1990

Comparison of the effects of ACTH-(1-24), methylprednisolone, aprotinin, and norepinephrine in a model of hemorrhagic shock in rats

scientific article published on 01 June 1993

Corrigendum to “Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors” [Eur. J. Pharmacol. 477 (2003) 227–234]

scholarly article published in European Journal of Pharmacology

Different cholinergic pathways are involved in the improvement induced by CCK-8 and by ACTH-(1-24) in massive acute hemorrhage, in rats

scientific article published on 01 July 1987

Effect of ACTH-(1-24) on the volume of circulating blood and on regional blood flow in rats bled to hypovolemic shock

scientific article published on 01 December 1989

Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome.

scientific article

Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock.

scientific article

Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors

scientific article published in September 2003

Haematological changes induced by the intravenous injection of CCK-8 in rats subjected to haemorrhagic shock

scientific article published on 01 February 1988

High blood levels of nitric oxide in rats subjected to prolonged respiratory arrest and their modulation during adrenocorticotropin-induced resuscitation

scientific article published on 01 January 1999

Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.

scientific article

Influence of ACTH-(1-24) on metabolic acidosis and hypoxemia induced by massive hemorrhage in rats

scientific article published on April 1, 1992

Influence of TRH on regional blood flow and metabolic acidosis in a model of volume-controlled hemorrhagic shock in rats ⬇️

scientific article published on December 1, 1991

Influence of clonidine on the ACTH-induced behavioral syndrome

scientific article published on 01 June 1984

Influence of morphine on the reversal of haemorrhagic shock induced by cholinergic drugs

scientific article published on 01 May 1990

Influence of the intravenous administration of ACTH-(1-24) on the characteristics of brain, heart and spleen adrenoceptors of haemorrhage-shocked rats

scientific article published on 01 September 1988

Influence of vagotomy and of atropine on the anti-shock effect of adrenocorticotropin

scientific article published on 01 July 1986

Inhibition of nitric oxide synthases enhances the effect of ACTH in hemorrhagic shock

scientific article published on 01 January 1997

Intracerebroventricular injection of hemicholinium-3 prevents the ACTH-induced, but not the physostigmine-induced, reversal of hemorrhagic shock in rats

scientific article published on 01 January 1990

Involvement of the sympathetic nervous system in the cardiovascular effects of ACTH-(1-24) during hemorrhagic shock in rats

scientific article published on 01 May 1988

Lipid peroxidation triggers both c-Jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK) activation and neointimal hyperplasia induced by cessation of blood flow in the mouse carotid artery.

scientific article

MC(3) receptors are involved in the protective effect of melanocortins in myocardial ischemia/reperfusion-induced arrhythmias

scientific article published on 24 May 2002

Mechanism of action of the anti-shock effect of CCK-8: influence of CCK antagonists and of sympatholytic drugs

scientific article published on 01 January 1988

Melanocortin 4 receptor activation protects against testicular ischemia-reperfusion injury by triggering the cholinergic antiinflammatory pathway

scientific article

Melanocortin 4 receptor stimulation decreases pancreatitis severity in rats by activation of the cholinergic anti-inflammatory pathway.

scientific article published in May 2011

Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia

scientific article

Melanocortins and the cholinergic anti-inflammatory pathway.

scientific article published on January 2010

Melanocortins as potential therapeutic agents in severe hypoxic conditions

scientific article published on 17 April 2012

Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism

scientific article published on 10 April 2010

Melanocortins protect against brain damage and counteract cognitive decline in a transgenic mouse model of moderate Alzheimer׳s disease

scientific article

Melanocortins protect against multiple organ dysfunction syndrome in mice ⬇️

scientific article published on February 1, 2011

Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways.

scientific article published in October 2013

Modulation of the JAK/ERK/STAT signaling in melanocortin-induced inhibition of local and systemic responses to myocardial ischemia/reperfusion.

scientific article published on 25 March 2013

Molecular changes induced in rat liver by hemorrhage and effects of melanocortin treatment.

scientific article

NDP-α-MSH attenuates heart and liver responses to myocardial reperfusion via the vagus nerve and JAK/ERK/STAT signaling

scientific article published on 15 October 2015

NDP-α-MSH induces intense neurogenesis and cognitive recovery in Alzheimer transgenic mice through activation of melanocortin MC4 receptors

scientific article

Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins.

scientific article published on 5 June 2007

Nicotine reverses hemorrhagic shock in rats ⬇️

scientific article published on April 1, 1991

Nuclear factor-kappaB as a target of cyclosporin in acute hypovolemic hemorrhagic shock.

scientific article

Olive oil-provoked bile-dependent absorption of heparin from gastro-intestinal tract in rats

Physostigmine has a life-saving effect in rats subjected to prolonged respiratory arrest

scientific article published on 01 September 1997

Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*.

scientific article published in March 2012

Protective effects of the melanocortin analog NDP-α-MSH in rats undergoing cardiac arrest.

scientific article

Reperfusion-induced arrhythmias and lethality are reduced by a 2KDa heparin fragment

scientific article published on 01 January 1995

Resuscitating effect of melanocortin peptides after prolonged respiratory arrest.

scientific article

Serotonin is involved in the ACTH-induced reversal of hemorrhagic shock in anesthetized rats.

scientific article published in April 1996

Sodium deoxycholate promotes the absorption of heparin administered orally, probably by acting on gastrointestinal mucosa, in rats

scientific article published on 01 March 1985

Survival rate after early treatment for acute type-A aortic dissection with ACTH-(1-24).

scientific article published in August 2001

TRH reverses the ECG and EEG ischemic changes induced by massive hemorrhage in rats

scientific article published on 01 January 1991

The adrenocorticotropic hormone (ACTH)-induced reversal of hemorrhagic shock

scientific article published on 01 December 1989

The disaccharide trehalose inhibits proinflammatory phenotype activation in macrophages and prevents mortality in experimental septic shock.

scientific article published in January 2007

The reversal of experimental hemorrhagic shock induced by nicotine and dimethylphenylpiperazinium is adrenal-dependent

scientific article published on 01 April 1996

Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery

scientific article

Tumour necrosis factor-alpha as a target of melanocortins in haemorrhagic shock, in the anaesthetized rat.

scientific article

Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia.

scientific article published on 25 March 2013

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