List of works - Rosa Sirianni

17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha.

scientific article published on 2 February 2010

1α,25-Dihydroxyvitamin D₃ inhibits the human H295R cell proliferation by cell cycle arrest: a model for a protective role of vitamin D receptor against adrenocortical cancer

scientific article published on 20 November 2013

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

scientific article

Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation.

scientific article published on October 2005

Antioxidant activity of a Mediterranean food product: "fig syrup"

scientific article published on 28 February 2011

Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines

scientific article published on 25 September 2013

DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

scientific article published on 11 July 2013

Effects of tri-iodothyronine on alternative splicing events in the coding region of cytochrome P450 aromatase in immature rat Sertoli cells.

scientific article published in August 2001

GPER Signaling in Spermatogenesis and Testicular Tumors

scientific article

Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax.

scientific article

Human sperm liver receptor homolog-1 (LRH-1) acts as a downstream target of the estrogen signaling pathway

scientific article published on 4 August 2015

Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.

scientific article

Inhibition of Src tyrosine kinase stimulates adrenal androgen production.

scientific article published on June 2003

Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells

scientific article published on 13 August 2009

Nandrolone and stanozolol induce Leydig cell tumor proliferation through an estrogen-dependent mechanism involving IGF-I system.

scientific article

Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation

scientific article published on 10 August 2012

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

scientific article

Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.

scientific article

Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: A review of in vitro studies ⬇️

scientific article published on November 27, 2012

Role of estrogen receptors and g protein-coupled estrogen receptor in regulation of hypothalamus-pituitary-testis axis and spermatogenesis

scientific article

Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

scientific journal article

Statins reduce intratumor cholesterol affecting adrenocortical cancer growth

scientific article published on 16 June 2020

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines

scientific article

Synthesis of a new bis(indolyl)methane that inhibits growth and induces apoptosis in human prostate cancer cells

scientific article published on 20 August 2013

Targeting Estrogen Receptor-α Reduces Adrenocortical Cancer (ACC) Cell Growthin Vitroandin Vivo: Potential Therapeutic Role of Selective Estrogen Receptor Modulators (SERMs) for ACC Treatment ⬇️

scientific article published on October 16, 2012

The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1.

scientific article

The mechanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model.

scientific article

The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

scientific article

cAMP-dependent regulation of CYP19 gene in rabbit preovulatory granulosa cells and corpus luteum.

scientific article

List of works by Rosa Sirianni

17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha.

1α,25-Dihydroxyvitamin D₃ inhibits the human H295R cell proliferation by cell cycle arrest: a model for a protective role of vitamin D receptor against adrenocortical cancer

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

Antiestrogens upregulate estrogen receptor beta expression and inhibit adrenocortical H295R cell proliferation.

Antioxidant activity of a Mediterranean food product: "fig syrup"

Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines

DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

Effects of tri-iodothyronine on alternative splicing events in the coding region of cytochrome P450 aromatase in immature rat Sertoli cells.

GPER Signaling in Spermatogenesis and Testicular Tumors

Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax.

Human sperm liver receptor homolog-1 (LRH-1) acts as a downstream target of the estrogen signaling pathway

Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.

Inhibition of Src tyrosine kinase stimulates adrenal androgen production.

Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells

Nandrolone and stanozolol induce Leydig cell tumor proliferation through an estrogen-dependent mechanism involving IGF-I system.

Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.

Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: A review of in vitro studies ⬇️

Role of estrogen receptors and g protein-coupled estrogen receptor in regulation of hypothalamus-pituitary-testis axis and spermatogenesis

Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

Statins reduce intratumor cholesterol affecting adrenocortical cancer growth

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines

Synthesis of a new bis(indolyl)methane that inhibits growth and induces apoptosis in human prostate cancer cells

Targeting Estrogen Receptor-α Reduces Adrenocortical Cancer (ACC) Cell Growthin Vitroandin Vivo: Potential Therapeutic Role of Selective Estrogen Receptor Modulators (SERMs) for ACC Treatment ⬇️

The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1.

The mechanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model.

The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

cAMP-dependent regulation of CYP19 gene in rabbit preovulatory granulosa cells and corpus luteum.