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List of works by Alessandra Soriani

A role for PKCtheta in outside-in alpha(IIb)beta3 signaling.

scientific article published in March 2006

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

scientific article

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms

scientific article published on 24 May 2019

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells

scientific article

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

scientific article published on 13 February 2020

CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-β1.

scientific article

Cancer Exosomes as Conveyors of Stress-Induced Molecules: New Players in the Modulation of NK Cell Response ⬇️

scientific article published on 31 January 2019

Cancer extracellular vesicles as novel regulators of NK cell response

scientific article published on 30 November 2019

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.

scientific article published on 18 October 2016

Chemerin regulates NK cell accumulation and endothelial cell morphogenesis in the decidua during early pregnancy

scientific article

Chemokine regulation of innate lymphoid cell tissue distribution and function

scientific article published on 14 February 2018

Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma.

scientific article published on 22 October 2013

DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction

scientific article

Defective expression of the T-cell receptor-CD3 zeta chain in T-cell acute lymphoblastic leukaemia

scientific article published in January 2003

Dendritic cells modulate c-kit expression on the edge between activation and death

scientific article published on 25 February 2019

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

scientific article published on 21 November 2011

Drug-induced senescent Multiple Myeloma cells elicit NK cell proliferation by direct or exosome-mediated IL-15 trans-presentation.

scientific article published on 24 April 2018

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

scientific article published on 16 February 2017

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

scientific article published on 12 June 2015

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

scientific article published on 13 January 2017

Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation

scientific article

Hitting More Birds with a Stone: Impact of TGF-β on ILC Activity in Cancer

scientific article published on 05 January 2020

How Mucosal Epithelia Deal with Stress: Role of NKG2D/NKG2D Ligands during Inflammation.

scientific article published on 20 November 2017

IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.

scientific article published in May 2012

In situ study of chemokine and chemokine-receptor expression in Kaposi sarcoma.

scientific article published in October 2003

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

scientific article published on December 2016

Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of STAT3.

scientific article published on 17 May 2013

Key Role of the CD56CD16 Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells

Low doses of subcutaneous interleukin-2 plus interferon-alpha do not induce thyroid function alterations in advanced renal cell carcinoma patients

scientific article published in October 2004

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

scientific article published in May 2018

NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma

scientific article

NKG2D and Its Ligands: "One for All, All for One".

scientific article

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.

scientific article published on 25 September 2017

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

scientific article published on 5 August 2016

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

scientific article

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

scientific article published on 22 January 2015

Prevalence of coeliac disease in Italian patients affected by Addison's disease

scientific article published on 01 March 2006

Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration

scientific article published on March 2003

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.

scientific article

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

scientific article published in September 2006

Recruitment of circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy

scientific article

Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta

scientific article

Senescent cells: Living or dying is a matter of NK cells

scientific article published on 27 February 2019

Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.

scientific article published on 23 March 2015

TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells

scientific article published on 09 July 2019

Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy

scientific article published in January 2016

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells.

scientific article published on 07 January 2014

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

scientific article

The Senescence-Associated Secretory Phenotype (SASP) in the Challenging Future of Cancer Therapy and Age-Related Diseases

scientific article published on 21 December 2020

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors

scientific article published on 11 April 2019

The human antibody fragment DIATHIS1 specific for CEACAM1 enhances natural killer cell cytotoxicity against melanoma cell lines in vitro

scientific article

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

scientific article published on 27 December 2012

Translating the anti-myeloma activity of Natural Killer cells into clinical application

scientific article published on 10 October 2018

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

scientific article published on 2 December 2016

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