List of works - Joshua I Goldhaber

A modified local control model for Ca2+ transients in cardiomyocytes: junctional flux is accompanied by release from adjacent non-junctional RyRs

scientific article published on 3 January 2014

Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling.

scientific article published on 20 January 2005

Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice

scientific article published on 19 July 2010

Burst pacemaker activity of the sinoatrial node in sodium-calcium exchanger knockout mice.

scientific article published on 20 July 2015

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

scientific journal article

Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity

scientific article

Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+ /Ca2+ exchange knockout mice.

scientific article published on 27 March 2017

Distinct features of calcium handling and β-adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction

scientific article published on 23 August 2020

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit

scientific article

Effect of metabolic inhibition on couplon behavior in rabbit ventricular myocytes

scientific article

Effects of physical exercise training in syndrome X

scientific article published on 01 January 1993

Embryonic stem cell-derived cardiac myocytes are not ready for human trials

scientific article

Endothelium-dependent vasodilators do not cause propagated intercellular Ca2+ waves in vascular endothelial monolayers.

scientific article

Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux.

scientific article published on 17 November 2005

Excitation-contraction coupling in single guinea-pig ventricular myocytes exposed to hydrogen peroxide

scientific article published on 01 May 1994

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1

scientific journal article

Genetic manipulation of cardiac Na+/Ca2+ exchange expression

scientific journal article

Gi alpha 1-mediated cardiac electrophysiological remodeling and arrhythmia in hypertrophic cardiomyopathy

scientific article

Heterogeneity of transverse-axial tubule system in mouse atria: Remodeling in atrial-specific Na+-Ca2+ exchanger knockout mice.

scientific article

High-density lipoprotein increases intracellular calcium levels by releasing calcium from internal stores in human endothelial cells.

scientific article published on April 1999

Homozygous overexpression of the Na+-Ca2+ exchanger in mice: evidence for increased transsarcolemmal Ca2+ fluxes

scientific article published on 01 March 2007

Integrins protect cardiomyocytes from ischemia/reperfusion injury.

scientific article published on 16 September 2013

Intracellular Ca(2+) dynamics and the stability of ventricular tachycardia.

scientific article

Is the ryanodine receptor a target for antiarrhythmic therapy?

scientific article published on 01 May 2006

Local regulation of the threshold for calcium sparks in rat ventricular myocytes: role of sodium-calcium exchange.

scientific article

Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice

scientific article published on 30 August 2006

Mechanisms of excitation-contraction coupling failure during metabolic inhibition in guinea-pig ventricular myocytes.

scientific article published in November 1991

Metabolic inhibition activates a non-selective current through connexin hemichannels in isolated ventricular myocytes.

scientific article

Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling.

scientific article

Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity

scientific article

Movement of vault particles visualized by GFP-tagged major vault protein.

scientific article

Na+ currents are required for efficient excitation-contraction coupling in rabbit ventricular myocytes: a possible contribution of neuronal Na+ channels.

scientific article published on November 2010

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

scientific article

Na+/Ca2+ exchanger knockout mice: plasticity of cardiac excitation-contraction coupling.

scientific article published on March 2007

Na/Ca exchange and contraction of the heart.

scientific article published on 12 June 2013

Next-generation pacemakers: from small devices to biological pacemakers.

scientific article published on 16 November 2017

Novel features of the rabbit transverse tubular system revealed by quantitative analysis of three-dimensional reconstructions from confocal images

scientific article published on 16 May 2008

Oxygen free radicals and excitation-contraction coupling.

scientific article

Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms

scientific article published on 11 February 2012

Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop

scientific article

Putative ryanodine receptors in the sarcolemma of ventricular myocytes

scientific article published on 01 May 2000

Recapitulation of the embryonic cardiovascular progenitor cell niche

scientific article

Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.

scientific article published on 26 May 2015

Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages

scientific article

Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies

scholarly article

Reverse electrical remodeling in rats with heart failure and preserved ejection fraction

scientific article published on 04 October 2018

Role of inotropic agents in the treatment of heart failure.

scientific article

Safety and hemodynamic effects of intravenous triiodothyronine in advanced congestive heart failure.

scientific article

Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart

scientific article

Spontaneously beating cardiomyocytes derived from white mature adipocytes.

scientific article

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides

scientific article published on 01 February 2002

The role of E2F-1 and downstream target genes in mediating ischemia/reperfusion injury in vivo ⬇️

scientific article published on September 22, 2011

Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice

scientific article published on 9 November 2016

Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure ⬇️

scientific article published on May 1, 2011

List of works by Joshua I Goldhaber

A modified local control model for Ca2+ transients in cardiomyocytes: junctional flux is accompanied by release from adjacent non-junctional RyRs

Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling.

Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice

Burst pacemaker activity of the sinoatrial node in sodium-calcium exchanger knockout mice.

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity

Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+ /Ca2+ exchange knockout mice.

Distinct features of calcium handling and β-adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit

Effect of metabolic inhibition on couplon behavior in rabbit ventricular myocytes

Effects of physical exercise training in syndrome X

Embryonic stem cell-derived cardiac myocytes are not ready for human trials

Endothelium-dependent vasodilators do not cause propagated intercellular Ca2+ waves in vascular endothelial monolayers.

Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux.

Excitation-contraction coupling in single guinea-pig ventricular myocytes exposed to hydrogen peroxide

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1

Genetic manipulation of cardiac Na+/Ca2+ exchange expression

Gi alpha 1-mediated cardiac electrophysiological remodeling and arrhythmia in hypertrophic cardiomyopathy

Heterogeneity of transverse-axial tubule system in mouse atria: Remodeling in atrial-specific Na+-Ca2+ exchanger knockout mice.

High-density lipoprotein increases intracellular calcium levels by releasing calcium from internal stores in human endothelial cells.

Homozygous overexpression of the Na+-Ca2+ exchanger in mice: evidence for increased transsarcolemmal Ca2+ fluxes

Integrins protect cardiomyocytes from ischemia/reperfusion injury.

Intracellular Ca(2+) dynamics and the stability of ventricular tachycardia.

Is the ryanodine receptor a target for antiarrhythmic therapy?

Local regulation of the threshold for calcium sparks in rat ventricular myocytes: role of sodium-calcium exchange.

Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice

Mechanisms of excitation-contraction coupling failure during metabolic inhibition in guinea-pig ventricular myocytes.

Metabolic inhibition activates a non-selective current through connexin hemichannels in isolated ventricular myocytes.

Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling.

Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity

Movement of vault particles visualized by GFP-tagged major vault protein.

Na+ currents are required for efficient excitation-contraction coupling in rabbit ventricular myocytes: a possible contribution of neuronal Na+ channels.

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

Na+/Ca2+ exchanger knockout mice: plasticity of cardiac excitation-contraction coupling.

Na/Ca exchange and contraction of the heart.

Next-generation pacemakers: from small devices to biological pacemakers.

Novel features of the rabbit transverse tubular system revealed by quantitative analysis of three-dimensional reconstructions from confocal images

Oxygen free radicals and excitation-contraction coupling.

Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms

Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop

Putative ryanodine receptors in the sarcolemma of ventricular myocytes

Recapitulation of the embryonic cardiovascular progenitor cell niche

Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.

Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages

Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies

Reverse electrical remodeling in rats with heart failure and preserved ejection fraction

Role of inotropic agents in the treatment of heart failure.

Safety and hemodynamic effects of intravenous triiodothyronine in advanced congestive heart failure.

Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart

Spontaneously beating cardiomyocytes derived from white mature adipocytes.

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides

The role of E2F-1 and downstream target genes in mediating ischemia/reperfusion injury in vivo ⬇️

Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice

Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure ⬇️