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List of works by Nicole J Horwood

A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis

scientific article

Activated T lymphocytes support osteoclast formation in vitro

scientific article published on 01 November 1999

Alarmins: awaiting a clinical response

scientific article

Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

scientific article published on 19 November 2007

Breast cancer cells interact with osteoblasts to support osteoclast formation

scientific article published on 01 October 1999

Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production

scientific article published in March 2006

Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

scientific article

Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment.

scientific article

Dual-specificity phosphatase 1-null mice exhibit spontaneous osteolytic disease and enhanced inflammatory osteolysis in experimental arthritis

scientific article published on 01 July 2012

Effect of glycosphingolipids on osteoclastogenesis and osteolytic bone diseases.

scientific article published on 23 August 2012

Enhanced osseous implant fixation with strontium-substituted bioactive glass coating.

scientific article

Fibroblastic stromal cells express receptor activator of NF-kappa B ligand and support osteoclast differentiation.

scientific article

Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to GAlert.

scientific article published on 19 April 2018

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis

scientific article published on 09 January 2020

Glycine and glycine receptor signalling in non-neuronal cells.

scientific article published on 20 August 2009

Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.

scientific article published on 27 April 2015

Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1.

scientific article

High-efficiency gene transfer into nontransformed cells: utility for studying gene regulation and analysis of potential therapeutic targets.

scientific article

Immune cells and bone: coupling goes both ways.

scientific article published on January 2013

Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo

scientific article

Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.

scientific article published on February 1998

Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation

scientific article

Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissues.

scientific article published in November 1999

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response.

scientific article published on 14 March 2015

Lymphocyte-derived cytokines in inflammatory arthritis.

scientific article published on April 2008

Macrophage Polarization and Bone Formation: A review.

scientific article

Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation

scientific article

OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.

scientific article published on 27 January 2014

Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells

scientific article published on 01 November 1998

Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfecta

scientific article published on 16 October 2013

Potential of mesenchymal stem cell therapy

scientific article published on November 2007

Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation.

scientific article

Selective inhibition of TNFR1 reduces osteoclast numbers and is differentiated from anti-TNF in a LPS-driven model of inflammatory bone loss.

scientific article

Strain dependent differences in glucocorticoid-induced bone loss between C57BL/6J and CD-1 mice.

scientific article

Strontium can increase some osteoblasts without increasing hematopoietic stem cells.

scientific article published on 30 October 2007

TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival.

scientific article

TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells

scientific article

Th17 cells, not IL-17+ γδ T cells, drive arthritic bone destruction in mice and humans

scientific article published on 07 January 2011

The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells

scientific article published on September 2007

Treg cells suppress osteoclast formation: a new link between the immune system and bone

article

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