List of works - Stephen Tait

A fate worse than death: apoptosis as an oncogenic process

scientific article published on July 2016

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

scientific article published on 27 October 2011

African swine fever virus infection of porcine aortic endothelial cells leads to inhibition of inflammatory responses, activation of the thrombotic state, and apoptosis.

scientific article published on November 2001

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

scientific article

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

scientific article

Author Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

scientific article published on 01 February 2020

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax

scientific article published on 19 April 2002

Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53 ⬇️

scientific article published on March 21, 2011

Cancer therapy-induced PAFR ligand expression: any role for caspase activity?

scientific article published on 10 March 2017

Characterization of cytoplasmic caspase-2 activation by induced proximity.

scientific article

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin

scientific article published on 18 February 2017

Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

scientific article published on 01 December 2018

DNA: leukemia's secret weapon of bone mass destruction

scientific article published on 28 January 2013

Depletion of mitochondria in mammalian cells through enforced mitophagy.

scientific article published on 22 December 2016

Die another way--non-apoptotic mechanisms of cell death

scientific article (publication date: 15 May 2014)

Differential retrotranslocation of mitochondrial Bax and Bak.

scientific article

Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy

scientific article

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

scientific article published in June 2007

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.

scientific article

Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

scientific article published on 13 August 2018

Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway

scientific article published on 06 August 2007

Killing the Killer: PARC/CUL9 promotes cell survival by destroying cytochrome C

scientific article published on 15 July 2014

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death.

scientific article

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

scientific article

MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis

scientific article

MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.

scientific article published on 27 January 2017

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

scientific article published in August 2004

Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

scientific article published on November 2000

Mechanisms of mitophagy: putting the powerhouse into the doghouse.

scientific article published on 12 April 2016

Mito-priming as a method to engineer Bcl-2 addiction.

scientific article

Mitochondria and cell death: outer membrane permeabilization and beyond

scientific article (publication date: September 2010)

Mitochondria and pathogen immunity: from killer to firestarter

scientific article published on 17 May 2019

Mitochondria and the hallmarks of cancer.

scientific article

Mitochondria are required for pro-ageing features of the senescent phenotype.

scientific article

Mitochondria as multifaceted regulators of cell death

scientific article published on 21 October 2019

Mitochondrial DNA in inflammation and immunity

scientific article published on 23 March 2020

Mitochondrial apoptosis: killing cancer using the enemy within.

scientific article published on 17 March 2015

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

scientific article published on 26 July 2018

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

scientific article published in 2024

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

scientific article published on 28 August 2017

Mitochondrial regulation of cell death.

scientific article published on September 2013

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Parkin inhibits necroptosis to prevent cancer

scientific article published on 01 August 2019

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

scientific article

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation

scientific article

RIPK3 promotes adenovirus type 5 activity

scientific article

Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

scientific article published on 26 April 2004

Retrograde signaling from autophagy modulates stress responses.

scientific article published on 28 February 2017

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

scientific article published on 20 May 2020

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

scientific journal article

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

scientific article published on 23 August 2002

Targeting BCL-2 regulated apoptosis in cancer.

scientific article

Targeting Immunogenic Cell Death in Cancer

scientific article published on 11 November 2020

Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance

scientific article published in December 2016

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

scientific article

Using enhanced-mitophagy to measure autophagic flux.

scientific article

Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition

scientific article published on 13 August 2020

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

scientific article published on 21 November 2013

p53 REEPs to sow ER-mitochondrial contacts

scientific article published on 01 September 2018

List of works by Stephen Tait

A fate worse than death: apoptosis as an oncogenic process

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

African swine fever virus infection of porcine aortic endothelial cells leads to inhibition of inflammatory responses, activation of the thrombotic state, and apoptosis.

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

Author Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax

Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53 ⬇️

Cancer therapy-induced PAFR ligand expression: any role for caspase activity?

Characterization of cytoplasmic caspase-2 activation by induced proximity.

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin

Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

DNA: leukemia's secret weapon of bone mass destruction

Depletion of mitochondria in mammalian cells through enforced mitophagy.

Die another way--non-apoptotic mechanisms of cell death

Differential retrotranslocation of mitochondrial Bax and Bak.

Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.

Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori

Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway

Killing the Killer: PARC/CUL9 promotes cell survival by destroying cytochrome C

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death.

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis

MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

Mechanisms of mitophagy: putting the powerhouse into the doghouse.

Mito-priming as a method to engineer Bcl-2 addiction.

Mitochondria and cell death: outer membrane permeabilization and beyond

Mitochondria and pathogen immunity: from killer to firestarter

Mitochondria and the hallmarks of cancer.

Mitochondria are required for pro-ageing features of the senescent phenotype.

Mitochondria as multifaceted regulators of cell death

Mitochondrial DNA in inflammation and immunity

Mitochondrial apoptosis: killing cancer using the enemy within.

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

Mitochondrial regulation of cell death.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Parkin inhibits necroptosis to prevent cancer

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation

RIPK3 promotes adenovirus type 5 activity

Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

Retrograde signaling from autophagy modulates stress responses.

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

Targeting BCL-2 regulated apoptosis in cancer.

Targeting Immunogenic Cell Death in Cancer

Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Using enhanced-mitophagy to measure autophagic flux.

Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

p53 REEPs to sow ER-mitochondrial contacts