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List of works by Joao S Silva

A cascade of cytokines mediates mechanical inflammatory hypernociception in mice.

scientific article

A morphometric study of maternal smoking on apoptosis in the syncytiotrophoblast

scientific article published on 01 April 1998

Actinobacillus actinomycetemcomitans-induced periodontal disease in mice: patterns of cytokine, chemokine, and chemokine receptor expression and leukocyte migration

scientific article published on 22 March 2005

Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients ⬇️

scientific article published on 01 October 2012

Adjunct effect of the antimicrobial photodynamic therapy to an association of non-surgical and surgical periodontal treatment in modulation of gene expression: a human study.

scientific article

Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection

scientific article published on 17 March 2008

An activated murine B cell lymphoma line (A-20) produces a factor-like activity which is functionally related to human natural killer cell stimulatory factor

scientific article published on 01 December 1992

Antigens from Rhipicephalus sanguineus ticks elicit potent cell-mediated immune responses in resistant but not in susceptible animals.

scientific article

Association of human T lymphotropic virus 1 amplification of periodontitis severity with altered cytokine expression in response to a standard periodontopathogen infection.

scientific article published in February 2010

B cell-deficient mice display enhanced susceptibility to Paracoccidioides brasiliensis Infection.

scientific article published on 14 June 2013

B cells are involved in the modulation of pathogenic gut immune response in food-allergic enteropathy.

scientific article

B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells.

scientific article published on 16 November 2012

CCR2 signaling contributes to the differentiation of protective inflammatory dendritic cells in Leishmania braziliensis infection

scientific article

CCR5-Dependent Homing of T Regulatory Cells to the Tumor Microenvironment Contributes to Skin Squamous Cell Carcinoma Development

scientific article published on 13 September 2017

CD25+ T cell depletion impairs murine squamous cell carcinoma development via modulation of antitumor immune responses

scientific article published on 16 February 2012

CD4+CD25+T Cells in Skin Lesions of Patients with Cutaneous Leishmaniasis Exhibit Phenotypic and Functional Characteristics of Natural Regulatory T Cells

scientific article published on 17 March 2006

CD44+/CD24- cells and lymph node metastasis in stage I and II invasive ductal carcinoma of the breast.

scientific article published on 29 June 2011

CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses.

scientific article published on 20 February 2018

Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.

scientific article

Caspase-11-dependent IL-1α release boosts Th17 immunity against Paracoccidioides brasiliensis

scientific article published on 19 August 2019

Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis

scientific article published on 01 May 2008

Chemokine production and leukocyte recruitment to the lungs of Paracoccidioides brasiliensis-infected mice is modulated by interferon-gamma.

scientific article published on August 2003

Chemokines, inflammation and Trypanosoma cruzi infection.

scientific article

Cloning and characterization of a gene encoding an immunoglobulin-binding receptor on the cell surface of some members of the family Trypanosomatidae

scientific article

Congenital Chagas disease: time to screen pregnant women?

scientific article

Corrigendum to "Immunocompetent Mice Model for Dengue Virus Infection"

scientific article published on 06 September 2018

Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans

scientific article published on 01 October 2007

Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties.

scientific article

Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase

scientific article published on 22 November 2011

Detrimental role of endogenous nitric oxide in host defence against Sporothrix schenckii.

scientific article

Distinct Roles of Th17 and Th1 Cells in Inflammatory Responses Associated with the Presentation of Paucibacillary Leprosy and Leprosy Reactions

scientific article published on 20 April 2017

Doxycycline and Benznidazole Reduce the Profile of Th1, Th2, and Th17 Chemokines and Chemokine Receptors in Cardiac Tissue from Chronic Trypanosoma cruzi-Infected Dogs

scientific article published on September 2016

Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct saliva-induced cellular recruitment into BALB/c mice ear

scientific article

Effect of growth hormone on in vitro osteogenesis and gene expression of human osteoblastic cells is donor-age-dependent

scientific article published on 01 May 2008

Effect of salivary gland extract of Leishmania vector, Lutzomyia longipalpis, on leukocyte migration in OVA-induced immune peritonitis.

scientific article published in August 2005

Effects of Antimicrobial Photodynamic Therapy on Transforming Growth Factor-β1 Levels in the Gingival Crevicular Fluid ⬇️

scientific article published on February 1, 2013

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis.

scientific article

Endothelin-1 induces neutrophil recruitment in adaptive inflammation via TNFα and CXCL1/CXCR2 in mice

scientific article published on 09 February 2012

Enhancement of Th1 lung immunity induced by recombinant Mycobacterium bovis Bacillus Calmette-Guerin attenuates airway allergic disease

scientific article published on 05 October 2009

Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL-17A expression and invasiveness of the tumor

scientific article published on 16 May 2013

Evidences of the cooperative role of the chemokines CCL3, CCL4 and CCL5 and its receptors CCR1+ and CCR5+ in RANKL+ cell migration throughout experimental periodontitis in mice

scientific article published on 04 January 2010

Experimental periodontitis in mice selected for maximal or minimal inflammatory reactions: increased inflammatory immune responsiveness drives increased alveolar bone loss without enhancing the control of periodontal infection

scientific article published on 07 October 2008

Expression of apoptosis mediators p53 and caspase 3, 7, and 9 in chronic rhinosinusitis with nasal polyposis.

scientific article published on May 2014

Expression of suppressors of cytokine signaling in diseased periodontal tissues: a stop signal for disease progression?

scientific article

Factors involved in the T helper type 1 and type 2 cell commitment and osteoclast regulation in inflammatory apical diseases.

scientific article published in February 2009

Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice.

scientific article published in May 2001

Functional interferences in host inflammatory immune response by airway allergic inflammation restrain experimental periodontitis development in mice

scientific article published on 09 December 2010

Genetic background affects the expansion of macrophage subsets in the lungs of Mycobacterium tuberculosis-infected hosts.

scientific article published on 3 February 2016

Hematopoietic SCT modulates gut inflammation in experimental inflammatory bowel disease.

scientific article published on 15 March 2010

Human leukocyte antigen-G expression after kidney transplantation is associated with a reduced incidence of rejection.

scientific article published on 26 November 2007

Human mucosal leishmaniasis: Neutrophils infiltrate areas of tissue damage that express high levels of Th17-related cytokines

scientific article published on 01 October 2010

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

scientific article published on 14 May 2010

IL-4 regulates susceptibility to intestinal inflammation in murine food allergy.

scientific article

IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment

scientific article

Immunoendocrinology of the thymus in Chagas disease

scientific article published on 22 September 2011

In vitro and in vivo trypanocidal activity of H2bdtc-loaded solid lipid nanoparticles

scientific article (publication date: May 2014)

Increased type 1 chemokine expression in experimental Chagas disease correlates with cardiac pathology in beagle dogs

scientific article published on 19 June 2010

Inducible cyclooxygenase released prostaglandin mediates immunosuppression in acute phase of experimental Trypanosoma cruzi infection.

scientific article published in October 2005

Inhibition of leukocyte rolling by nitric oxide during sepsis leads to reduced migration of active microbicidal neutrophils.

scientific article

Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors.

scientific article published on January 2014

Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection ⬇️

scientific article published on January 1, 1992

Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth.

scientific article

Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response

scientific article published on 31 May 2016

Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines?

scientific article

Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii.

scientific article published on 10 November 2011

Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2A Receptor to Promote the Establishment of Infection

scientific article

Leukotriene B(4) induces nitric oxide synthesis in Trypanosoma cruzi-infected murine macrophages and mediates resistance to infection

scientific article

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

scientific article

MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4

scientific article published on 14 April 2005

Mast cells control insulitis and increase Treg cells to confer protection against STZ-induced type 1 diabetes in mice

scientific article published on 14 August 2015

Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps.

scientific article published on 12 October 2012

Matrix metalloproteinases, their physiological inhibitors and osteoclast factors are differentially regulated by the cytokine profile in human periodontal disease

scientific article published on 01 August 2004

Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model

scientific article published on 27 February 2017

Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus.

scientific article

NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis.

scientific article

Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1α, TNF-α and LTB4

scientific article published on 01 August 2006

Nitric oxide and TNFalpha effects in experimental autoimmune encephalomyelitis demyelination

scientific article published on 15 August 2007

Nitric oxide inhibits neutrophil migration by a mechanism dependent on ICAM-1: role of soluble guanylate cyclase

scientific article published on 18 April 2006

Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice.

scientific article

Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assay

scientific article

Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions.

scientific article

Nucleosides present on phlebotomine saliva induce immunossuppression and promote the infection establishment.

scientific article

Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection

scientific article published on 05 July 2016

Oleic acid modulation of the immune response in wound healing: A new approach for skin repair

article

Organometallic gold(iii) complexes with hybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity

scientific article published on 3 February 2017

PD-1 blockage delays murine squamous cell carcinoma development.

scientific article published on 12 September 2013

Parasite Detection in Visceral Leishmaniasis Samples by Dye-Based qPCR Using New Gene Targets of Leishmania infantum and Crithidia

scientific article published on 8 August 2023

Periodontitis and arthritis interaction in mice involves a shared hyper-inflammatory genotype and functional immunological interferences

scientific article published on 29 April 2010

Polymorphic sites at the immunoregulatory CTLA-4 gene are associated with chronic chagas disease and its clinical manifestations.

scientific article published on 24 October 2013

Prolonged survival of allografts induced by mycobacterial Hsp70 is dependent on CD4+CD25+ regulatory T cells.

scientific article

Quantification of parasite burden of Trypanosoma cruzi and identification of Discrete Typing Units (DTUs) in blood samples of Latin American immigrants residing in Barcelona, Spain

scientific article published on 04 June 2020

Reappraisal of the immunopathogenesis of disseminated leishmaniasis: in situ and systemic immune response ⬇️

scientific article published on July 2, 2011

Reduction of ICAM-1 expression by carbon monoxide via soluble guanylate cyclase activation accounts for modulation of neutrophil migration.

scientific article published on 27 March 2010

Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

scholarly article

Regulatory T cells migrate to airways via CCR4 and attenuate the severity of airway allergic inflammation

scientific article published on 06 February 2013

Relevance of the myeloid differentiation factor 88 (MyD88) on RANKL, OPG, and nod expressions induced by TLR and IL-1R signaling in bone marrow stromal cells.

scientific article published in February 2015

Role of dystrophin in acute Trypanosoma cruzi infection.

scientific article published on 4 August 2014

Role of interleukin (IL)-18 in experimental paracoccidioidomycosis

scientific article published on 05 March 2008

Saliva of Rhipicephalus sanguineus tick impairs T cell proliferation and IFN-γ-induced macrophage microbicidal activity

scientific article published on 01 July 1998

Stromal cell-derived factor-1 production by spleen cells is affected by nitric oxide in protective immunity against blood-stage Plasmodium chabaudi CR in C57BL/6j mice.

scientific article published on October 2003

Strong and persistent microbial and inflammatory stimuli overcome the genetic predisposition to higher matrix metalloproteinase-1 (MMP-1) expression: a mechanistic explanation for the lack of association of MMP1-1607 single-nucleotide polymorphism g

scientific article published on 29 July 2009

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.

scientific article published on 12 January 2018

TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection

scientific article published on 25 March 2020

Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis

scientific article

The DNA Sensor AIM2 Protects against Streptozotocin-Induced Type 1 Diabetes by Regulating Intestinal Homeostasis via the IL-18 Pathway

scientific article published on 14 April 2020

The adjuvant effect of jacalin on the mouse humoral immune response to trinitrophenyl and Trypanosoma cruzi.

scientific article

The binding of CCL2 to the surface of Trypanosoma cruzi induces chemo-attraction and morphogenesis

scientific article published on 08 December 2006

The broad effects of the functional IL-10 promoter-592 polymorphism: modulation of IL-10, TIMP-3, and OPG expression and their association with periodontal disease outcome

scientific article published on 25 August 2008

The essential role of IFN-γ in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice

scientific article published on 25 January 2008

The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection.

scientific article

The left lung is preferentially targeted during experimental paracoccidioidomycosis in C57BL/6 mice.

scientific article published on 02 October 2013

The role of nitric oxide in the pathogenesis of Chagas disease.

scientific article published in May 2003

Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ12,14-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4+CD25-FOXP3+ Cells.

scientific article published on 31 October 2016

Tick saliva induces regulatory dendritic cells: MAP-kinases and Toll-like receptor-2 expression as potential targets

scientific article published on 22 September 2009

Tick saliva inhibits differentiation, maturation and function of murine bone-marrow-derived dendritic cells.

scientific article published in February 2005

Tick saliva inhibits the chemotactic function of MIP-1α and selectively impairs chemotaxis of immature dendritic cells by down-regulating cell-surface CCR5

scientific article published on 22 October 2007

Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection.

scientific article published on 23 February 2017

Toll-like receptor 9 signaling in dendritic cells regulates neutrophil recruitment to inflammatory foci following Leishmania infantum infection.

scientific article

Tr-1-like CD4+CD25-CD127-/lowFOXP3- cells are the main source of interleukin 10 in patients with cutaneous leishmaniasis due to Leishmania braziliensis.

scientific article

Tumor necrosis factor-related apoptosis-inducing ligand mediates the resolution of allergic airway inflammation induced by chronic allergen inhalation

scientific article published on 26 February 2014

Tumor-infiltrating CD4+ T lymphocytes in early breast cancer reflect lymph node involvement

scientific article published on 30 June 2006

Tumour necrosis factor-alpha and leukotriene B(4) mediate the neutrophil migration in immune inflammation.

scientific article

Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in cardiac patients.

scientific article

Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection - Future Perspectives.

scientific article published on 22 July 2016

Vasopressin release during endotoxaemic shock in mice lacking inducible nitric oxide synthase.

scientific article published on 22 June 2005

α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active on Trypanosoma cruzi.

scientific article published on 8 February 2013

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