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List of works by Bjoern Titz

A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product

scientific article published on 02 April 2015

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clin

scientific article published on 11 April 2018

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology asses

scientific article published on 13 March 2018

A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes

scientific article published on 12 February 2019

Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis

scientific article

Activity of MMP-19 inhibits capillary-like formation due to processing of nidogen-1

scientific article

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

scientific article published on 20 September 2016

Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects

scientific article published on 22 August 2015

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.

scientific article

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/−Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes

scientific article published on 01 June 2016

Analysis of Proteomic Data for Toxicological Applications

Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology

scientific article published on 07 September 2019

Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures

scientific article published on 02 January 2019

CRAF R391W is a melanoma driver oncogene

scientific article published on 08 June 2016

Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma

scientific article

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.

scientific article published on 23 December 2016

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice

scientific article

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis

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Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma

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Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis

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Erratum: Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

scientific article published on 09 March 2016

Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1

scientific article

JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma

scientific article published on 06 September 2016

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells.

scientific article

Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration

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Novel conserved assembly factor of the bacterial flagellum.

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Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer

scientific article published on 3 August 2016

Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin

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Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors

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Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification

scientific article published on 15 September 2018

Proteomics for systems toxicology

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Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice

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Systems toxicological assessment of the mentholated Tobacco Heating System 2.2 aerosol revealed reduced cellular and molecular exposure effects compared with cigarette smoke

Systems toxicology meta-analysis of assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract

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The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.

scientific article published on 5 February 2007

The binary protein interactome of Treponema pallidum--the syphilis spirochete

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The protein network of bacterial motility

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The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

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The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

scientific article published on 02 March 2020

The systems toxicology challenge

The systems toxicology challenge: Marker of exposure response identification in blood

Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints

scientific article published on 4 September 2017

Transcriptional activators in yeast

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What do we learn from high-throughput protein interaction data?

scientific article