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List of works by Debra A Schwinn

A Critical Period for the Role of Thyroid Hormone in Development of Renalα-Adrenergic Receptors ⬇️

scientific article published on July 1, 1997

A two-allele PstI RFLP for the alpha-1C adrenergic receptor gene (ADRA1C)

scientific article published on August 1, 1992

APOE polymorphism is associated with risk of severe sepsis in surgical patients.

scientific article

Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants.

scientific article published on 7 January 2002

Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group

scientific article published on 01 September 1998

Alpha 1-adrenergic receptor regulation: basic science and clinical implications

scientific article

Alpha-adrenergic mRNA subtype expression in the human nasal turbinate

scientific article published on 01 July 2007

Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg?

scientific article published in December 2005

Alpha1-adrenoceptor subtypes and lower urinary tract symptoms

scientific article published on March 2008

Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway

scientific article published on 16 November 2015

Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways

scientific article

Alpha2-adrenergic receptors in human dorsal root ganglia: predominance of alpha2b and alpha2c subtype mRNAs

scientific article published on 01 April 2000

Anesthesiology physician scientists in academic medicine: a wake-up call

scientific article

Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery.

scientific article

Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery

scientific article published on 06 January 2010

Atrial natriuretic peptide.

scientific article

Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

scientific article published in October 2000

Beta-adrenergic receptor function in surgical patients

scientific article published on 01 March 1991

Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest.

scientific article published in August 1995

Cardiopulmonary bypass and circulatory arrest increase endothelin-1 production and receptor expression in the lung

scientific article published on 01 April 1997

Cardiovascular effects of intravenous triiodothyronine in patients undergoing coronary artery bypass graft surgery. A randomized, double-blind, placebo- controlled trial. Duke T3 study group

scientific article published on 01 March 1996

Case 4-2011: malignant hyperthermia in cardiac surgery

scientific article published on 21 March 2011

Characteristics of a human prostate stromal cell line related to its use in a stromal-epithelial coculture model for the study of cancer chemoprevention.

scientific article published on May 2005

Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes.

scientific article published on February 1998

Characterization of alpha-adrenoceptor subtypes in the corpus cavernosum of patients undergoing sex change surgery

scientific article published on 01 November 1999

Comprehensive history of 3-year and accelerated US medical school programs: a century in review

article

Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway

scientific article published on 16 November 2011

Desensitization of myocardial beta-adrenergic receptors and deterioration of left ventricular function after brain death

scientific article published on 01 September 1995

Desensitization of myocardial beta-adrenergic receptors during cardiopulmonary bypass. Evidence for early uncoupling and late downregulation ⬇️

scientific article published on December 1, 1991

Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.

scientific article published on August 2005

Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics.

scientific article

Distribution of beta 3-adrenoceptor mRNA in human tissues

scientific article published on 01 April 1995

Do not resuscitate (DNR) orders during surgery: ethical foundations for institutional policies in the United States

scientific article published on 01 April 1995

Effect of chronic and acute thyroid hormone reduction on perioperative outcome.

scientific article published on July 1997

Effects of androgen deprivation on prostate alpha 1-adrenergic receptors

scientific article published on 01 August 1996

Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung

scientific article published on 01 June 1996

Endogenous circulating sympatholytic factor in orthostatic intolerance.

scientific article

Esmolol improves left ventricular function via enhanced beta-adrenergic receptor signaling in a canine model of coronary revascularization.

scientific article

Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.

scientific article published on 12 July 2005

Fostering interprofessional teamwork in an academic medical center: Near-peer education for students during gross medical anatomy.

scientific article published on 28 May 2014

Genetic Polymorphisms and the Risk of Stroke After Cardiac Surgery

article

Genetic factors contribute to bleeding after cardiac surgery.

scientific article published on 9 May 2005

Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery

scientific article published on 30 April 2007

Genetics and patient outcome after cardiac surgery: unravelling translational findings ⬇️

scientific article published on December 1, 2011

Genetics infuses new life into human physiology: implications of the human genome project for anesthesiology and perioperative medicine

scientific article published on 01 February 2002

Genomics and the circulation.

scientific article published on 14 May 2004

Genotyping without phenotyping: does it really matter?

scientific article published on 01 January 2013

Human G(alpha q): cDNA and tissue distribution

scientific article

Hypotension resistant to therapy with alpha receptor agonists complicating cardiopulmonary bypass: lithium as a potential cause.

scientific article published on May 1996

Identification, Quantification, and Localization of mRNA for Three Distinct Alpha1Adrenergic Receptor Subtypes in Human Prostate ⬇️

scientific article published on 01 August 1993

In situ hybridization: identification of rare mRNAs in human tissues.

scientific article published in May 1997

Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

scientific article

Intraoperative monitoring of brainstem auditory evoked potentials following emergency evacuation of a cerebellar vascular malformation

scientific article

Limitations of genetic findings that are not in Hardy-Weinberg equilibrium.

scientific article published in February 2008

Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements ⬇️

scientific article published on May 15, 1992

Management of a difficult intubation during acute myocardial ischemia following a failed angioplasty ⬇️

scientific article published on June 1, 1992

Mechanistic insights into the role of alpha1adrenergic receptors in lower urinary tract symptoms.

scientific article published in August 2004

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

scientific article published on 23 March 2009

Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery?

scientific article published in May 2004

Molecular pharmacology of human alpha1-adrenergic receptors: unique features of the alpha 1a-subtype

scientific article

Multiple potential regulatory elements in the 5' flanking region of the beta 3-adrenergic receptor.

scientific article

Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor.

scientific article published in March 1998

Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease

scientific article

New developments in cardiovascular adrenergic receptor pharmacology: Molecular mechanisms and clinical relevance ⬇️

scientific article published on February 1, 1998

New paradigms in cardiovascular medicine: emerging technologies and practices: perioperative genomics.

scientific article

Pharmacogenomics and perioperative medicine--implications for modern clinical practice.

scientific article

Pharmacogenomics of β-Adrenergic Receptor Physiology and Response to β-Blockade ⬇️

scientific article published on September 29, 2011

Pharmacologic characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype

scientific article

Pharmacology of tamsulosin: Saturation-binding isotherms and competition analysis using cloned α1-adrenergic receptor subtypes ⬇️

scientific article published on September 15, 1997

Research in academic medical centers: two threats to sustainable support.

scientific article published in May 2015

Stimulation of α1a adrenergic receptors induces cellular proliferation or antiproliferative hypertrophy dependent solely on agonist concentration

scientific article

Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor.

scientific article

Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation.

scientific article published on 05 August 2015

The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits.

scientific article published on 29 November 2007

The new age of medical genomics.

scientific article

Time-variable medical education innovation in context.

scientific article

Understanding the TXA seizure connection

scientific article

Understanding the transition to acute illness: the promise of perioperative genomics.

scientific article published on June 2008

Update on human alpha1-adrenoceptor subtype signaling and genomic organization.

scientific article

Writing successful research proposals for medical science

scientific article published on 01 June 1998

alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels

scientific article published on 01 December 1995

alpha1-Adrenoceptor subtype selectivity and lower urinary tract symptoms.

scientific article

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