List of works - Paolo Durigutto

A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome.

scientific article

Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice

scientific article published on 6 June 2014

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

scientific article published on February 2016

Complement Activation and Thrombin Generation by MBL Bound to β2-Glycoprotein I

scientific article published on 05 August 2020

Complement C1q and C8 deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness

scientific article published on 04 August 2008

Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery

scientific article published on 07 December 2015

Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating

scientific article published on 11 November 2015

Fluvastatin treatment inhibits leucocyte adhesion and extravasation in models of complement-mediated acute inflammation.

scientific article

In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions.

scientific article published on 26 July 2011

Innate immunity, through late complement components activation, contributes to the development of early vascular inflammation and morphologic alterations in experimental diabetes.

scientific article published on March 2011

Mannose-binding lectin is produced by vaginal epithelial cells and its level in the vaginal fluid is influenced by progesterone.

scientific article published on 21 August 2010

Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency

scientific article

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

scientific article published on 01 July 2018

Orchestration of inflammation and adaptive immunity in Borrelia burgdorferi-induced arthritis by neutrophil-activating protein A.

scientific article published on May 2013

Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo

scientific article published on 15 March 2007

Prevention of arthritis by locally synthesized recombinant antibody neutralizing complement component C5.

scientific article

Selective therapeutic control of C5a and the terminal complement complex by anti-C5 single-chain Fv in an experimental model of antigen-induced arthritis in rats

scientific article published on 01 April 2007

Targeted Delivery of Neutralizing Anti-C5 Antibody to Renal Endothelium Prevents Complement-Dependent Tissue Damage.

scientific article published on 6 September 2017

Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis

scientific article published on 15 June 2019

The Neutrophil-Activating Protein of Helicobacter pylori Crosses Endothelia to Promote Neutrophil Adhesion In Vivo

scientific article published on 01 February 2007

Treatment of experimental arthritis by targeting synovial endothelium with a neutralizing recombinant antibody to C5

scientific article published on 01 August 2012

List of works by Paolo Durigutto

A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome.

Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

Complement Activation and Thrombin Generation by MBL Bound to β2-Glycoprotein I

Complement C1q and C8 deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness

Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery

Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating

Fluvastatin treatment inhibits leucocyte adhesion and extravasation in models of complement-mediated acute inflammation.

In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions.

Innate immunity, through late complement components activation, contributes to the development of early vascular inflammation and morphologic alterations in experimental diabetes.

Mannose-binding lectin is produced by vaginal epithelial cells and its level in the vaginal fluid is influenced by progesterone.

Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

Orchestration of inflammation and adaptive immunity in Borrelia burgdorferi-induced arthritis by neutrophil-activating protein A.

Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo

Prevention of arthritis by locally synthesized recombinant antibody neutralizing complement component C5.

Selective therapeutic control of C5a and the terminal complement complex by anti-C5 single-chain Fv in an experimental model of antigen-induced arthritis in rats

Targeted Delivery of Neutralizing Anti-C5 Antibody to Renal Endothelium Prevents Complement-Dependent Tissue Damage.

Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis

The Neutrophil-Activating Protein of Helicobacter pylori Crosses Endothelia to Promote Neutrophil Adhesion In Vivo

Treatment of experimental arthritis by targeting synovial endothelium with a neutralizing recombinant antibody to C5