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List of works by Maria Rosário Almeida

Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy

scientific article published on 3 June 2008

Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity

scientific article

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

scientific article published on 24 March 2017

Clearance of extracellular misfolded proteins in systemic amyloidosis: Experience with transthyretin ⬇️

scientific article published on July 20, 2012

Comparative Studies of Two Transthyretin Variants with Protective Effects on Familial Amyloidotic Polyneuropathy: TTR R104H and TTR T119M

scientific article published on 01 April 2000

Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: relevance in drug design

scientific article

Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis

scientific article published on 20 May 2016

Dietary curcumin counteracts extracellular transthyretin deposition: Insights on the mechanism of amyloid inhibition

scientific article published on 13 October 2012

Epigallocatechin-3-Gallate as a Potential Therapeutic Drug for TTR-Related Amyloidosis: “In Vivo” Evidence from FAP Mice Models ⬇️

scientific article published on January 10, 2012

Familial amyloidotic polyneuropathy: transthyretin (prealbumin) variants in kindreds of Italian origin

article

Functional characterization of Arabidopsis thaliana transthyretin-like protein

scientific article

Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model

scientific article published on 2 October 2014

Haplotype analysis of common transthyretin mutations

scientific article published on 01 September 1995

Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin

scientific article

Impairment of autophagy by TTR V30M aggregates: in vivo reversal by TUDCA and curcumin

scientific article published on 6 July 2016

Interaction with human plasminogen system turns on proteolytic activity in Streptococcus agalactiae and enhances its virulence in a mouse model

scientific article published on 9 June 2007

Iodination of salicylic acid improves its binding to transthyretin

scientific article

Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors

scientific article

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors

scientific article published on 6 March 2009

Molecular Tweezers Targeting Transthyretin Amyloidosis

scientific article (publication date: 24 January 2014)

Natural polyphenols as modulators of TTR amyloidogenesis:in vitroandin vivoevidences towards therapy

article published in 2012

Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation ⬇️

scientific article published on July 2, 2011

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.

scientific article published on 23 February 2016

Screening and biochemical characterization of transthyretin variants in the Portuguese population

article

Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative

scientific article published on July 2004

Substrate specificity of transthyretin: identification of natural substrates in the nervous system

scientific article

TTR Leu 64 in an FAP kindred identified by PCR-RFLP analysis

TTR exon scanning in peripheral neuropathies

scientific article published on 01 May 1995

Targeting transthyretin amyloidosis in the eye with next-generation stabilizers: AT40 displays potent TTR stabilization in the human vitreous

scientific article published on 01 January 2019

The binding of xanthone derivatives to transthyretin.

scientific article published on 19 October 2005

Transthyretin Leu 68 in a form of cardiac amyloidosis

scientific article published on 01 November 1991

Transthyretin chemical chaperoning by flavonoids: Structure-activity insights towards the design of potent amyloidosis inhibitors.

scientific article

Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions.

scientific article

Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis ⬇️

scientific article published on 14 March 2019

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