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List of works by Kenn Holmbeck

A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.

scientific article published on 8 December 2015

A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation

scientific article

An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature

scientific article

Biglycan modulates angiogenesis and bone formation during fracture healing

scientific article published on 25 December 2013

Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo.

scientific article

Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion

scientific article

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.

scientific article

Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history

scientific article

Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream

scientific article published on 30 August 2016

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

scientific article

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

scientific article

Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo

scientific article published on 6 March 2006

GNAS transcripts in skeletal progenitors: evidence for random asymmetric allelic expression of Gs alpha

scientific article published on 12 June 2007

Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form

scientific article published on 01 June 2001

MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.

scientific article

MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D.

scientific article

MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

scientific article published on 10 December 2007

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

scientific article published on 01 October 1999

MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix.

scientific article

MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth

scientific article

MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.

scientific article

MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.

scientific article published on October 2009

MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding

scientific article published in December 2017

Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes

scientific article

Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury.

scientific article

Membrane-type 1 matrix metalloproteinase is required for normal alveolar development.

scientific article

Membrane-type MMPs are indispensable for placental labyrinth formation and development ⬇️

scientific article published on September 21, 2010

Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis

scientific journal article

Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis, and tooth eruption

scientific article published on 15 January 2016

On the role of MT1-MMP, a matrix metalloproteinase essential to collagen remodeling, in murine molar eruption and root growth

scientific article published on 01 December 2002

Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsα(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse

scientific article

Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

scientific article published on 12 September 2019

The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone.

scientific article

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

scientific article

Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia.

scientific article

WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling.

scientific article published on 11 April 2015

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

scientific article

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