List of works - Ami Aronheim

A novel approach for the identification of protein-protein interaction with integral membrane proteins.

scientific article

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

scientific article

A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.

scientific article

AP-1 repressor protein JDP-2: inhibition of UV-mediated apoptosis through p53 down-regulation

scientific article (publication date: May 2001)

ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.

scientific article published on 7 November 2016

ATF3, a novel cardiac therapeutic target: Beneficial or harmful?

scientific article published on 5 January 2017

ATF3-dependent cross-talk between cardiomyocytes and macrophages promotes cardiac maladaptive remodeling

scientific article published on 09 July 2015

Abstracts from the Fourteenth Rambam Research Day, December 7, 2017.

scientific article published on 29 January 2018

Activating Transcription 3's role in cardiac remodeling

scientific article published on 01 September 2017

Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy

scientific article (publication date: 2013)

Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells.

scientific article

Analysis and identification of protein-protein interactions using protein recruitment systems

scientific article published on 01 January 2000

Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

scientific article published on June 2007

B-cell factor 1 is required for optimal expression of the DRA promoter in B cells ⬇️

scientific article published on May 1, 1992

Cell-specific expression of helix-loop-helix transcription factors encoded by the E2A gene.

scientific article published on April 1993

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

scientific article

Correction: Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy.

scientific article

Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2

scientific article

Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT.

scientific article

Direct measurement of agonist binding to genetically engineered peptides of the acetylcholine receptor by selective T1 NMR relaxation

scientific article published on 01 March 1990

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family.

scientific article published on November 2003

Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes

scientific article

Docking interactions of the JNK scaffold protein WDR62.

scientific article published on November 2011

HBV X protein targets HIV Tat-binding protein 1.

scientific article

Heparanase is required for activation and function of macrophages.

scientific article

Host JDP2 expression in the bone marrow contributes to metastatic spread

scientific article published on 14 October 2015

Improved efficiency sos recruitment system: expression of the mammalian GAP reduces isolation of Ras GTPase false positives.

scientific article published on August 1997

Induction of terminal differentiation by the c-Jun dimerization protein JDP2 in C2 myoblasts and rhabdomyosarcoma cells

scientific article (publication date: 18 October 2002)

Insulin-producing cells contain a cell-specific repressor activity that functions through multiple E-box sequences

scientific article published on September 1, 1992

Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions

scientific article

JDP2 and ATF3 - bZIP repressors in cardiac remodeling

scientific article published on 01 April 2018

JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function

scientific article published on 28 February 2019

Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator

scientific article

Membrane recruitment systems for analysis of protein-protein interactions

scientific article

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

scientific article

Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcription

scientific article (publication date: 10 April 2003)

Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation

scientific article

Positive and negative regulation of insulin gene transcription.

scientific article

Protein recruitment systems for the analysis of protein +/- protein interactions

scientific article published on 01 May 2001

Protein recruitment systems for the analysis of protein-protein interactions.

scientific article

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

scientific article

Ras signaling pathway for analysis of protein-protein interactions in yeast and mammalian cells

scientific article published on January 2004

Response letter: "ATF3: A promoter or inhibitor of cardiac maladaptive remodeling"

scientific article published on 28 August 2015

Setting up an efficient and reliable screening method for novel c-Jun N-terminal kinase substrates.

scientific article published on 12 March 2000

TRE-dependent transcription activation by JDP2-CHOP10 association

scientific article

The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice

scientific article

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

scientific article

The Ras Recruitment System (RRS) for the Identification and Characterization of Protein-Protein Interactions

scientific article published on 01 January 2018

The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene

scientific article (publication date: 13 February 2004)

The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis

scientific article published on 10 November 2016

The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors

scientific article published on 27 May 2003

The ras recruitment system, a novel approach to the study of protein-protein interactions

scientific article

The role of basic leucine zipper protein-mediated transcription in physiological and pathological myocardial hypertrophy

scientific article

Tumor Growth Ameliorates Cardiac Dysfunction

scientific article published in 2023

WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis.

scientific article

c-Jun dimerization protein 2 (JDP2) deficiency promotes cardiac hypertrophy and dysfunction in response to pressure overload.

scientific article published on 6 September 2017

List of works by Ami Aronheim

A novel approach for the identification of protein-protein interaction with integral membrane proteins.

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.

AP-1 repressor protein JDP-2: inhibition of UV-mediated apoptosis through p53 down-regulation

ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.

ATF3, a novel cardiac therapeutic target: Beneficial or harmful?

ATF3-dependent cross-talk between cardiomyocytes and macrophages promotes cardiac maladaptive remodeling

Abstracts from the Fourteenth Rambam Research Day, December 7, 2017.

Activating Transcription 3's role in cardiac remodeling

Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy

Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells.

Analysis and identification of protein-protein interactions using protein recruitment systems

Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

B-cell factor 1 is required for optimal expression of the DRA promoter in B cells ⬇️

Cell-specific expression of helix-loop-helix transcription factors encoded by the E2A gene.

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

Correction: Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy.

Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2

Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT.

Direct measurement of agonist binding to genetically engineered peptides of the acetylcholine receptor by selective T1 NMR relaxation

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family.

Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes

Docking interactions of the JNK scaffold protein WDR62.

HBV X protein targets HIV Tat-binding protein 1.

Heparanase is required for activation and function of macrophages.

Host JDP2 expression in the bone marrow contributes to metastatic spread

Improved efficiency sos recruitment system: expression of the mammalian GAP reduces isolation of Ras GTPase false positives.

Induction of terminal differentiation by the c-Jun dimerization protein JDP2 in C2 myoblasts and rhabdomyosarcoma cells

Insulin-producing cells contain a cell-specific repressor activity that functions through multiple E-box sequences

Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions

JDP2 and ATF3 - bZIP repressors in cardiac remodeling

JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function

Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator

Membrane recruitment systems for analysis of protein-protein interactions

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcription

Phosphorylation of JDP2 on threonine-148 by the c-Jun N-terminal kinase targets it for proteosomal degradation

Positive and negative regulation of insulin gene transcription.

Protein recruitment systems for the analysis of protein +/- protein interactions

Protein recruitment systems for the analysis of protein-protein interactions.

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

Ras signaling pathway for analysis of protein-protein interactions in yeast and mammalian cells

Response letter: "ATF3: A promoter or inhibitor of cardiac maladaptive remodeling"

Setting up an efficient and reliable screening method for novel c-Jun N-terminal kinase substrates.

TRE-dependent transcription activation by JDP2-CHOP10 association

The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

The Ras Recruitment System (RRS) for the Identification and Characterization of Protein-Protein Interactions

The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene

The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis

The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors

The ras recruitment system, a novel approach to the study of protein-protein interactions

The role of basic leucine zipper protein-mediated transcription in physiological and pathological myocardial hypertrophy

Tumor Growth Ameliorates Cardiac Dysfunction

WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis.

c-Jun dimerization protein 2 (JDP2) deficiency promotes cardiac hypertrophy and dysfunction in response to pressure overload.