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List of works by Alexander Spiel

Age-dependent effect of targeted temperature management on outcome after cardiac arrest

scientific article published on 08 October 2018

Androgen deprivation decreases prostate specific antigen in the absence of tumor: implications for interpretation of PSA results

scientific article published on 01 March 2014

Cardiac biomarkers predict mortality in emergency patients presenting with atrial fibrillation

scientific article published on 10 November 2018

Cold infusions alone are effective for induction of therapeutic hypothermia but do not keep patients cool after cardiac arrest

scientific article published on 22 January 2007

Duffy antigen modifies the chemokine response in human endotoxemia

scientific article published in January 2008

Editor's Choice-Progress in the chain of survival and its impact on outcomes of patients admitted to a specialized high-volume cardiac arrest center during the past two decades.

scientific article published on 30 November 2015

Effect of therapeutic mild hypothermia initiated by cold fluids after cardiac arrest on haemostasis as measured by thrombelastography.

scientific article published on 13 March 2008

Effects of carbon monoxide inhalation during experimental endotoxemia in humans

scientific article published on 19 November 2004

Effects of low dose endotoxemia on endothelial progenitor cells in humans

scientific article published on 09 May 2007

Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel

scientific article

Effects of prasugrel on platelet inhibition during systemic endotoxaemia: a randomized controlled trial

scientific article published in November 2012

Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia.

scientific article published in April 2008

Ethnic differences in plasma levels of interleukin-8 (IL-8) and granulocyte colony stimulating factor (G-CSF)

scientific article published on 01 January 2007

Expert Opinion: Meditation and Cardiovascular Health: What is the Link?

scientific article published on 18 December 2019

Hemostasis in cardiac arrest patients treated with mild hypothermia initiated by cold fluids

scientific article published on 29 April 2009

High Platelet Reactivity after Transition from Cangrelor to Ticagrelor in Hypothermic Cardiac Arrest Survivors with ST-Segment Elevation Myocardial Infarction

scientific article published on 21 February 2020

Hyperkalemia: A persisting risk. A case report and update on current management

scientific article published on 02 June 2020

Hypoxic liver injury after in- and out-of-hospital cardiac arrest: Risk factors and neurological outcome

scientific article published on 01 March 2019

Improvement of outcome prediction of hospitalized patients with COVID-19 by a dual marker strategy using high-sensitive cardiac troponin I and copeptin

scientific article published on 15 November 2021

In vivo profile of the human leukocyte microRNA response to endotoxemia.

scientific article

In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model.

scientific article

Increased Citrullinated Histone H3 Levels in the Early Post-Resuscitative Period Are Associated with Poor Neurologic Function in Cardiac Arrest Survivors-A Prospective Observational Study

scientific article published on 01 October 2019

Increased Fibrinolysis as a Specific Marker of Poor Outcome After Cardiac Arrest

scientific article published on 01 October 2018

Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration

scientific article published on 08 February 2011

Influence of the Duffy antigen on pharmacokinetics and pharmacodynamics of recombinant monocyte chemoattractant protein (MCP-1, CCL-2) in vivo.

scientific article

Initial electrical frequency predicts survival and neurological outcome in out of hospital cardiac arrest patients with pulseless electrical activity.

scientific article published on 2 February 2018

Interspecies differences in coagulation profile

Interspecies differences in coagulation profile

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

scientific article published on July 2013

Mortality in patients resuscitated from out-of-hospital cardiac arrest based on automated blood cell count and neutrophil lymphocyte ratio at admission

scientific article

NO-synthase inhibition in sepsis

scientific article published on 01 April 2006

Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis

scientific article published on 6 October 2017

Pharmacokinetics and pharmacodynamics of the dual FII/FX inhibitor BIBT 986 in endotoxin-induced coagulation.

scientific article published on 4 April 2007

Platelet function in patients with acute coronary syndrome (ACS) predicts recurrent ACS

scientific article (publication date: December 2006)

Platelet hyperfunction is decreased by additional aspirin loading in patients presenting with myocardial infarction on daily aspirin therapy.

scientific article published in June 2010

Potent irreversible P2Y12 inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial

scientific article

Predicting spontaneous conversion to sinus rhythm in symptomatic atrial fibrillation: The ReSinus score

scientific article published on 17 September 2020

Prediction of Successful Pharmacological Cardioversion in Acute Symptomatic Atrial Fibrillation: The Successful Intravenous Cardioversion for Atrial Fibrillation (SIC-AF) Score

scientific article published on 31 March 2022

Pronounced platelet hyperfunction in patients with cardiac arrest achieving restoration of spontaneous circulation

scientific article

Quality of post arrest care does not differ by time of day at a specialized resuscitation center.

scientific article

Racial differences in endotoxin-induced tissue factor-triggered coagulation.

scientific article

Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

scientific article published on 01 November 2003

Reparixin, a specific interleukin-8 inhibitor, has no effects on inflammation during endotoxemia.

scientific article published in January 2007

Role of von Willebrand factor in vascular disease.

scientific article published on January 2009

Seasonal variability and influence of outdoor temperature on body temperature of cardiac arrest victims

scientific article

Simvastatin and rosuvastatin mobilize Endothelial Progenitor Cells but do not prevent their acute decrease during systemic inflammation.

scientific article published on 22 April 2008

Single dose granulocyte colony-stimulating factor markedly enhances shear-dependent platelet function in humans

scientific article

Standard blood laboratory values as a clinical support tool to distinguish between SARS-CoV-2 positive and negative patients

scientific article published on 30 April 2021

Surface cooling for induction of mild hypothermia in conscious healthy volunteers - a feasibility trial

scientific article published on October 22, 2011

The BRASH syndrome: an interaction of bradycardia, renal failure, AV block, shock and hyperkalemia

scientific article published on 25 July 2020

The Impact of the COVID-19 Pandemic on Incidences of Atrial Fibrillation and Electrical Cardioversion at a Tertiary Care Emergency Department: An Inter- and Intra-year Analysis

scientific article published on 04 December 2020

The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction.

scientific article

The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor-mediated platelet function in ST-elevation and non-ST-elevation acute myocardial infarction

The effect of percutaneous coronary intervention in patients suffering from ST-segment elevation myocardial infarction complicated by out-of-hospital cardiac arrest on 30 days survival

scientific article published on 23 October 2012

The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia

scientific article published on 01 December 2005

Validation of rotation thrombelastography in a model of systemic activation of fibrinolysis and coagulation in humans.

scientific article

Vernakalant is superior to ibutilide for achieving sinus rhythm in patients with recent-onset atrial fibrillation: a randomized controlled trial at the emergency department

scientific article

profile of the human leukocyte microRNA response to endotoxemia

von Willebrand factor in cardiovascular disease: focus on acute coronary syndromes.

scientific article published on March 2008