List of works by Philippe Büscher

A CATT negative result after treatment for human African trypanosomiasis is no indication for cure

scientific article

A LiTat 1.5 variant surface glycoprotein-derived peptide with diagnostic potential for Trypanosoma brucei gambiense

scientific article published on 4 January 2013

A comparative evaluation of parasitological tests and a PCR for Trypanosoma evansi diagnosis in experimentally infected water buffaloes

scientific article

A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models

scientific article (publication date: August 2014)

A proline racemase based PCR for identification of Trypanosoma vivax in cattle blood

scientific article published on 8 January 2014

A semi-quantitative ELISA for detection of Trypanosoma brucei gambiense specific antibodies in serum and cerebrospinal fluid of sleeping sickness patients.

scientific article published on May 1998

A simplified and standardized polymerase chain reaction format for the diagnosis of leishmaniasis

scientific article

APOLs with low pH dependence can kill all African trypanosomes

scientific article published on 18 September 2017

Accordance and concordance of PCR and NASBA followed by oligochromatography for the molecular diagnosis of Trypanosoma brucei and Leishmania

scientific article published on 14 May 2010

Acidiphily in pteridophytes: Assessment of the role of root cation‐exchange properties

An experimental latex agglutination test for antibody detection in human African trypanosomiasis

scientific article published on December 1, 1991

Aparasitemic serological suspects in Trypanosoma brucei gambiense human African trypanosomiasis: a potential human reservoir of parasites?

scientific article published on 24 May 2006

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

scientific article published on 12 April 2016

Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

scientific article (publication date: 2013)

Atypical human infections by animal trypanosomes

scientific article

Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness

scientific article

Blood–cerebrospinal fluid barrier and intrathecal immunoglobulins compared to field diagnosis of central nervous system involvement in sleeping sickness

Canine Trypanosoma evansi infection in Afghanistan

scientific article published on 20 July 2013

Canine Trypanosoma evansi infection introduced into Germany

scientific article published in September 2012

Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016.

scientific article published on July 2017

Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness

scientific article

Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5.

scientific article published on 9 May 2012

Charting methods to monitor the operational performance of ELISA method for the detection of antibodies against trypanosomes

scientific article

Comparative in vitro isolation of Trypanosoma theileri from cattle in Belgium

scientific article published on March 2000

Comparison of different DNA preparation protocols for PCR diagnosis of Human African Trypanosomosis in Côte d'Ivoire

scientific article published in June 2002

Comparison of operational criteria for treatment outcome in gambiense human African trypanosomiasis.

scientific article published on 17 February 2009

Comparison of serological tests for Trypanosoma evansi natural infections in water buffaloes from north Vietnam

scientific article published on September 2000

Control of parasitemia and survival during Trypanosoma brucei brucei infection is related to strain-dependent ability to produce IL-4.

scientific article published in October 1996

Cost-effectiveness of algorithms for confirmation test of human African trypanosomiasis

scientific article

Cross-reactivity of anti-galactocerebroside autoantibodies with a Trypanosoma brucei proteolipidic epitope.

scientific article published on March 2000

DIAGNOSTIC TOOLS FOR HUMAN AFRICAN TRYPANOSOMIASIS ELIMINATION AND CLINICAL TRIALS: THE DITECT-HAT PROJECT

Detection of African animal trypanosomes: the haematocrit centrifugation technique compared to PCR with samples stored on filter paper or in DNA protecting buffer.

scientific article

Detection of light subunit neurofilament and glial fibrillary acidic protein in cerebrospinal fluid of Trypanosoma brucei gambiense-infected patients.

scientific article published on January 1999

Development and evaluation of an ITS1 "Touchdown" PCR for assessment of drug efficacy against animal African trypanosomosis

scientific article published on 13 March 2014

Development of a bio-inkjet printed LAMP test kit for detecting human African trypanosomiasis

scientific article published on 22 October 2020

Development of a latex agglutination test with recombinant variant surface glycoprotein for serodiagnosis of surra

scientific article published on 6 September 2014

Diagnosis of African Trypanosomiasis

Diagnosis of Persistent Fever in the Tropics: Set of Standard Operating Procedures Used in the NIDIAG Febrile Syndrome Study

scientific article

Diagnosis of Visceral Leishmaniasis Using Peripheral Blood Microscopy in Ethiopia: A Prospective Phase-III Study of the Diagnostic Performance of Different Concentration Techniques Compared to Tissue Aspiration

scientific article

Diagnosis of human African trypanosomiasis in 2001

scientific article published on January 2001

Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study

scientific article

Diagnostic accuracy of a new Leishmania PCR for clinical visceral leishmaniasis in Nepal and its role in diagnosis of disease

scientific article

Diagnostic accuracy of loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples

scientific article

Diagnostic accuracy of molecular amplification tests for human African trypanosomiasis--systematic review

scientific article

Diagnostic accuracy of the Leishmania OligoC-TesT and NASBA-Oligochromatography for diagnosis of leishmaniasis in Sudan ⬇️

scientific article

Different trypanozoan species possess CD8 dependent lymphocyte triggering factor-like activity

scientific article published on April 1996

Direct detection and identification of African trypanosomes by fluorescence in situ hybridization with peptide nucleic acid probes

scientific article

Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?

scientific article published on 19 January 2018

Epidemiology of Trypanosoma evansi and Trypanosoma vivax in domestic animals from selected districts of Tigray and Afar regions, Northern Ethiopia

scientific article

Equine trypanosomosis: enigmas and diagnostic challenges

scientific article published on 15 May 2019

Equivalence trial of melarsoprol and nifurtimox monotherapy and combination therapy for the treatment of second-stage Trypanosoma brucei gambiense sleeping sickness

scientific article

Establishment of a panel of reference Trypanosoma evansi and Trypanosoma equiperdum strains for drug screening.

scientific article

Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis

scientific article

Evaluation of LATEX/T.b.gambiense for mass screening of Trypanosoma brucei gambiense sleeping sickness in Central Africa

scientific article

Evaluation of an EDTA version of CATT/Trypanosoma brucei gambiense for serological screening of human blood samples

scientific article published on January 2002

Evaluation of serodiagnostic tests for T.b. gambiense human African trypanosomiasis in southern Sudan.

scientific article

Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T b gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa

scientific article

Evaluation of variant specific trypanolysis tests for serodiagnosis of human infections with Trypanosoma brucei gambiense

scientific article published on December 1995

Evaluation of whole fresh blood and dried blood on filter paper discs in serological tests for Trypanosoma evansi in experimentally infected water buffaloes

scientific article published in February 2002

Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis.

scientific article published in November 2009

Expression of RoTat 1.2 cross-reactive variable antigen type in Trypanosoma evansi and T. equiperdum.

scientific article

Expression of Trypanosoma brucei gambiense Antigens in Leishmania tarentolae. Potential for Use in Rapid Serodiagnostic Tests (RDTs)

scientific article

Fast, simple, and low-cost test for drug-resistant pathogens

scientific article published in August 2005

Field evaluation of the CATT/Trypanosoma brucei gambiense on blood-impregnated filter papers for diagnosis of human African trypanosomiasis in southern Sudan.

scientific article published in November 2002

First Draft Genome Sequence of the Dourine Causative Agent: Trypanosoma Equiperdum Strain OVI.

scientific article published on 12 January 2017

Flow cytometry-based methods for assessing soluble scFv activities and detecting antigens in solution

scientific article

Follow-up of Card Agglutination Trypanosomiasis Test (CATT) positive but apparently aparasitaemic individuals in Côte d'Ivoire: evidence for a complex and heterogeneous population

article

Gambiense human african trypanosomiasis and immunological memory: effect on phenotypic lymphocyte profiles and humoral immunity

scientific article

General expression of RoTat 1.2 variable antigen type in Trypanosoma evansi isolates from different origin.

scientific article published on June 2001

Genome-Wide SNP Analysis Reveals Distinct Origins of Trypanosoma evansi and Trypanosoma equiperdum

scientific article published on 25 May 2017

Ghibe river basin in Ethiopia: present situation of trypanocidal drug resistance in Trypanosoma congolense using tests in mice and PCR-RFLP.

scientific article published on 26 April 2012

Grammomys surdaster, the Natural Host for Plasmodium berghei Parasites, as a Model to Study Whole-Organism Vaccines Against Malaria

scientific article published on 23 January 2017

Heterologous expression, purification and characterisation of the extracellular domain of trypanosome invariant surface glycoprotein ISG75.

scientific article published in May 2008

Host-parasite interactions in trypanosomiasis: on the way to an antidisease strategy

scientific article published on 21 January 2009

How can molecular diagnostics contribute to the elimination of human African trypanosomiasis?

scientific article published on 18 March 2015

How does Trypanosoma equiperdum fit into the Trypanozoon group? A cluster analysis by RAPD and multiplex-endonuclease genotyping approach.

scientific article published on May 2003

How to shorten patient follow-up after treatment for Trypanosoma brucei gambiense sleeping sickness.

scientific article published in February 2010

Human African trypanosomiasis

scientific article published on 30 June 2017

Human African trypanosomiasis control: Achievements and challenges

scientific article

Human African trypanosomiasis: a latex agglutination field test for quantifying IgM in cerebrospinal fluid.

scientific article published on January 1998

Human African trypanosomiasis: a review of non-endemic cases in the past 20 years.

scientific article published on 17 June 2011

Identification of Old World Leishmania spp. by specific polymerase chain reaction amplification of cysteine proteinase B genes and rapid dipstick detection

scientific article published on 18 December 2008

Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.

scientific article published on 2 October 2006

Identification of mimotopes with diagnostic potential for Trypanosoma brucei gambiense variant surface glycoproteins using human antibody fractions

scientific article

Identification of peptide mimotopes of Trypanosoma brucei gambiense variant surface glycoproteins

scientific article

Identification of stage biomarkers for human African trypanosomiasis.

scientific article

IgM quantification in the cerebrospinal fluid of sleeping sickness patients by a latex card agglutination test.

scientific article published on August 2002

Immune trypanolysis test with blood spotted on filter paper for epidemiological surveillance of sleeping sickness

article

Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for sleeping sickness diagnosis and staging

scientific article

Improved latex agglutination test for detection of antibodies in serum and cerebrospinal fluid of Trypanosoma brucei gambiense infected patients

scientific article published on May 1999

Innovative digital technologies for quality assurance of diagnosis of human African trypanosomiasis

scientific article published on 13 September 2018

Inter-laboratory ring trials to evaluate serological methods for dourine diagnosis

scientific article

Interleukin (IL)-6, IL-8 and IL-10 in serum and CSF of Trypanosoma brucei gambiense sleeping sickness patients before and after treatment.

scientific article published on May 2002

International study to evaluate PCR methods for detection of Trypanosoma cruzi DNA in blood samples from Chagas disease patients

scientific article

Intrathecal immune response pattern for improved diagnosis of central nervous system involvement in trypanosomiasis

scientific article published on 15 April 2003

Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice

scientific article

Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B

scholarly article by Gebrekrustos Mekonnen et al published September 2018 in PLoS Neglected Tropical Diseases

Killing of Trypanozoon Parasites by the Equine Cathelicidin eCATH1.

scientific article

Leishmania OligoC-TesT as a simple, rapid, and standardized tool for molecular diagnosis of cutaneous leishmaniasis in Peru.

scientific article published on 24 June 2009

Low specificities of HIV diagnostic tests caused by Trypanosoma brucei gambiense sleeping sickness

scientific article

Luminescent multiplex viability assay for Trypanosoma brucei gambiense

scientific article published on 15 July 2013

Melarsomine hydrochloride (Cymelarsan®) fails to cure horses with Trypanosoma equiperdum OVI parasites in their cerebrospinal fluid

scientific article published on 09 November 2018

Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo

scientific article (publication date: October 2014)

Molecular analysis of archived blood slides reveals an atypical human Trypanosoma infection

scientific article

Molecular diagnostics for sleeping sickness: what is the benefit for the patient?

scientific article

Molecular dipstick test for diagnosis of sleeping sickness.

scientific article published on August 2006

Multiplex-endonuclease genotyping approach (MEGA): a tool for the fine-scale detection of unlinked polymorphic DNA markers.

scientific article

Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

scientific article

Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness

scientific article

Neuro-inflammatory risk factors for treatment failure in "early second stage" sleeping sickness patients treated with pentamidine

scientific article published on November 2003

New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels

scientific article

New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients

scientific article published on 7 January 2013

Novel markers for treatment outcome in late-stage Trypanosoma brucei gambiense trypanosomiasis

scientific article published on July 2008

Novel primer sequences for polymerase chain reaction-based detection of Trypanosoma brucei gambiense

scientific article

Nucleic acid lateral flow tests for molecular diagnosis: an update

scientific article published on March 2011

Options for field diagnosis of human african trypanosomiasis

scientific article

Parasitological, serological and molecular survey of Trypanosoma evansi infection in dromedary camels from Cholistan Desert, Pakistan

scientific article

Passive surveillance of human African trypanosomiasis in Côte d'Ivoire: Understanding prevalence, clinical symptoms and signs, and diagnostic test characteristics

scientific article published on 30 August 2021

Performance of enzyme-linked immunosorbent assays for detection of antibodies against T. congolense and T. vivax in goats

scientific article published on October 2003

Performance of parasitological and molecular techniques for the diagnosis and surveillance of gambiense sleeping sickness

scientific article

Performance of serological tests for Trypanosoma evansi in experimentally inoculated goats

scientific article published on 01 October 2004

Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and Uganda

scientific article

Phylogenetic analysis of the Trypanosoma genus based on the heat-shock protein 70 gene

scientific article published on 12 May 2016

Population genetic structure and cladistic analysis of Trypanosoma brucei isolates.

scientific article published on September 2003

Population genetics of Trypanosoma brucei gambiense in sleeping sickness patients with treatment failures in the focus of Mbuji-Mayi, Democratic Republic of the Congo

scientific article

Presence of Trypanosoma theileri in Spanish Cattle

scientific article published on December 2008

Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo

scientific article

Rapid diagnostic test for sleeping sickness

scientific article published in March 2013

Rapid diagnostic tests for neurological infections in central Africa

scientific article published on 24 April 2013

Recent progress in molecular diagnosis of sleeping sickness

scientific article published on September 2012

Recombinant RoTat 1.2 variable surface glycoprotein as antigen for diagnosis of Trypanosoma evansi in dromedary camels.

scientific article published on April 2005

Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis

scientific article published on 07 July 2018

Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense

scientific article

Recombinant expression of trypanosome surface glycoproteins in Pichia pastoris for the diagnosis of Trypanosoma evansi infection.

scientific article published on 17 May 2013

Response to Li et al. and Shaw: Return of the ring – opportunities to challenge a hypothesis

Review Article: cerebrospinal fluid in human African trypanosomiasis: a key to diagnosis, therapeutic decision and post-treatment follow-up.

scientific article

Revisiting the immune trypanolysis test to optimise epidemiological surveillance and control of sleeping sickness in West Africa

scientific article

Ribosomal DNA analysis of tsetse and non-tsetse transmitted Ethiopian Trypanosoma vivax strains in view of improved molecular diagnosis

scientific article published on 16 February 2016

Sensitive detection of nucleic acids by PNA hybridization directed co-localization of fluorescent beads

scientific article published on April 2011

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study

scientific article

Sensitivity and specificity of HAT Sero-K-SeT, a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study

scientific article published on 9 May 2014

Short Ecotypic Characterization of Polypodium vulgare-Subspecies

Single centrifugation of cerebrospinal fluid in a sealed pasteur pipette for simple, rapid and sensitive detection of trypanosomes

article by T.W Miézan et al published May 2000 in Transactions of the Royal Society of Tropical Medicine and Hygiene

Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains

scientific article published on 25 October 2021

Specificity of malaria rapid diagnostic tests is affected by Trypanosoma brucei gambiense sleeping sickness

scientific article published on 15 October 2012

Stage determination and follow-up in sleeping sickness.

scientific article

Stage determination and therapeutic decision in human African trypanosomiasis: value of polymerase chain reaction and immunoglobulin M quantification on the cerebrospinal fluid of sleeping sickness patients in Côte d'Ivoire.

scientific article published in July 2003

Stage determination in sleeping sickness: comparison of two cell counting and two parasite detection techniques

scientific article published on 19 March 2013

Surra Sero K-SeT, a new immunochromatographic test for serodiagnosis of Trypanosoma evansi infection in domestic animals

scientific article

Susceptibility of Grammomys surdaster thicket rats to Trypanosoma brucei gambiense infection

scientific article published on September 2005

Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax

article

Systematic review on antigens for serodiagnosis of visceral leishmaniasis, with a focus on East Africa

scientific article published on 15 August 2019

T. cruzi OligoC-TesT: a simplified and standardized polymerase chain reaction format for diagnosis of Chagas disease

scientific article

The Trypanosoma cruzi satellite DNA OligoC-TesT and Trypanosoma cruzi kinetoplast DNA OligoC-TesT for diagnosis of Chagas disease: a multi-cohort comparative evaluation study.

scientific article

The challenge of Trypanosoma brucei gambiense sleeping sickness diagnosis outside Africa

scientific article published on December 2003

The complex health seeking pathway of a human African trypanosomiasis patient in Côte d'Ivoire underlines the need of setting up passive surveillance systems

scientific article published on 14 September 2020

The expression of RoTat 1.2 variable surface glycoprotein (VSG) in Trypanosoma evansi and T. equiperdum

scientific article published on October 2003

The invariant surface glycoprotein ISG75 gene family consists of two main groups in the Trypanozoon subgenus

scientific article published on 4 September 2006

The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense

scientific article

Towards a new reference test for surra in camels

scientific article published on 29 April 2009

Towards saliva-based screening for sleeping sickness?

scientific article published on July 2003

Treatment failure related to intrathecal immunoglobulin M (IgM) synthesis, cerebrospinal fluid IgM, and interleukin-10 in patients with hemolymphatic-stage sleeping sickness

scientific article

Treatment of human African trypanosomiasis--present situation and needs for research and development

scientific article

True versus apparent malaria infection prevalence: the contribution of a Bayesian approach

scientific article

Trypanosoma brucei gambiense: HMI-9 medium containing methylcellulose and human serum supports the continuous axenic in vitro propagation of the bloodstream form.

scientific article published on 24 February 2011

Trypanosoma brucei genomics and the challenge of identifying drug and vaccine targets

scientific article

Trypanosoma equiperdum: master of disguise or historical mistake?

scientific article

Trypanosoma evansi: Recent outbreaks in Europe

Trypanosoma evansi: cloning and expression in Spodoptera frugiperda [correction of fugiperda] insect cells of the diagnostic antigen RoTat1.2.

scientific article published on December 2001

Trypanosoma vivax GM6 antigen: a candidate antigen for diagnosis of African animal trypanosomosis in cattle.

scientific article

Trypanosoma vivax: a simplified protocol for in vivo growth, isolation and cryopreservation.

scientific article published on March 2004

Trypanosome infection in dromedary camels in Eastern Ethiopia: Prevalence, relative performance of diagnostic tools and host related risk factors

scientific article published on 18 April 2015

Trypanosomosis in goats: current status

scientific article

Universal PCR assays for the differential detection of all Old World Leishmania species.

scientific article

Untreated human infections by Trypanosoma brucei gambiense are not 100% fatal

scientific article

Use of the miniature anion exchange centrifugation technique to isolate Trypanosoma evansi from goats

scientific article

Validation of a PCR-oligochromatography test for detection of Trypanozoon parasites in a multicenter collaborative trial

scientific article published on 19 September 2007

Variable Surface Glycoprotein RoTat 1.2 PCR as a specific diagnostic tool for the detection of Trypanosoma evansi infections

scientific article

Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection

scientific article

Widespread occurrence of Trypanosoma vivax in bovines of tsetse- as well as non-tsetse-infested regions of Ethiopia: a reason for concern?

scientific article published on 20 July 2012

[Diagnosis of sleeping sickness stage: towards a new approach]

scientific article published on 01 December 2002

[Validity, cost and feasibility of the mAECT and CTC confirmation tests after diagnosis of African of sleeping sickness]

scientific article

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