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List of works by Paola Pizzo

A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling.

scientific article

Better to keep in touch: investigating inter-organelle cross-talk

scientific article published on 15 June 2020

Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain

scientific article

Ca(2+) signalling in the Golgi apparatus.

scientific article published on 12 February 2011

Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.

scientific article published on 7 August 2012

Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store-operated Ca2+ channels.

scientific article published on April 2010

Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products

scientific article published on 20 February 2007

Calcium dynamics in the peroxisomal lumen of living cells.

scientific article

Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors.

scientific article published on May 2009

Characterization of the ER-Targeted Low Affinity Ca(2+) Probe D4ER.

scientific article published on 02 September 2016

Characterization of the cytotoxic effect of extracellular ATP in J774 mouse macrophages.

scientific article published on December 1992

Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.

scientific article

Dynamic properties of an inositol 1,4,5-trisphosphate- and thapsigargin-insensitive calcium pool in mammalian cell lines

scientific article published on January 1997

Grp94 acts as a mediator of curcumin-induced antioxidant defence in myogenic cells.

scientific article published on April 2010

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

scientific article

Heterogeneity of Ca2+ handling among and within Golgi compartments.

scientific article published on August 2013

High content analysis of gamma-secretase activity reveals variable dominance of presenilin mutations linked to familial Alzheimer's disease.

scientific article

Highlighting the Endoplasmic Reticulum-Mitochondria connection: focus on Mitofusin 2.

scientific article published on 5 January 2018

Lighting Up Ca2+ Dynamics in Animal Models

scientific article published in 2021

Lipid rafts in lymphocyte activation.

scientific article published on June 2004

Loss of cysteine 584 impairs the storage and release, but not the synthesis of von Willebrand factor.

scientific article published on 18 September 2014

Lymphocyte lipid rafts: structure and function.

scientific article

Mitochondria, calcium and cell death: a deadly triad in neurodegeneration

scientific article

Mitochondria-endoplasmic reticulum choreography: structure and signaling dynamics.

scientific article

Mitochondrial alterations induced by aspirin in rat hepatocytes expressing mitochondrially targeted green fluorescent protein (mtGFP)

scientific article published on 01 March 1996

Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling

scientific article published on 13 April 2015

Mitofusin 2: from functions to disease.

scientific article published on 28 February 2018

Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production

scientific article

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

scientific article published on 25 April 2013

New insights on culture and calcium signalling in neurons and astrocytes from epileptic patients

scientific article published on 14 January 2011

On the role of Mitofusin 2 in endoplasmic reticulum-mitochondria tethering

scientific article published on 13 March 2017

Ontogenesis of chick iris intrinsic muscles: evidence for a smooth-to-striated muscle transition

scientific article published on 01 October 1993

PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca2+ homeostasis

scientific article published on 27 March 2019

Paradoxical Ca2+ rises induced by low external Ca2+ in rat hippocampal neurones.

scientific article published on 11 April 2003

Physiological T cell activation starts and propagates in lipid rafts.

scientific article published in January 2004

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.

scientific article

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.

scientific article

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.

scientific article published on 18 April 2006

Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks

scientific article published on 25 September 2020

Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake

scientific article published on 27 March 2009

Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia.

scientific article published on April 2005

SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition.

scientific article published on 11 December 2017

Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A₂ class

scientific article

Synergistic effect of extracellular adenosine 5'-triphosphate and tumor necrosis factor on DNA degradation

scientific article published on 01 November 1993

TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer

scientific article published on 26 January 2018

The Aging Mitochondria.

scientific article published on 9 January 2018

The C-terminal region of a Lys49 myotoxin mediates Ca2+ influx in C2C12 myotubes

scientific article published on 14 October 2009

The Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression.

scientific article

The endoplasmic reticulum-mitochondria coupling in health and disease: Molecules, functions and significance.

scientific article published on 12 January 2017

The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores

scientific article published on March 2004