List of works by Ruth J. Loos

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

15 years of genome-wide association studies and no signs of slowing down

scientific article published on 19 November 2020

A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin A1c With Implications for Glycemic Status in U.S. Hispanics/Latinos

scientific article published on 18 June 2019

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common loss-of-function variant is associated with lower vitamin B concentration in African Americans

scholarly article by Yao Hu et al published 21 June 2018 in Blood

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

scientific article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans

scientific article

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications.

scientific article published on 16 May 2018

A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study

scientific article (publication date: 2012)

A longitudinal study of eating behaviours in childhood and later eating disorder behaviours and diagnoses

scientific article published on 05 August 2019

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A quantitative study of unpaid caregiving in multiple sclerosis

scientific article published on 01 August 2000

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).

scientific article published on 5 February 2009

Across-cohort QC analyses of GWAS summary statistics from complex traits

scientific article

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

article published in 2015

Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study

scientific article

Adiposity-Mortality Relationships in Type 2 Diabetes, Coronary Heart Disease, and Cancer Subgroups in the UK Biobank, and Their Modification by Smoking

scientific article published on 03 July 2018

Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study

scientific article published on 28 March 2012

Advances in Exercise, Fitness, and Performance Genomics in 2015.

scientific article published on 13 May 2016

Advances in exercise, fitness, and performance genomics in 2010.

scientific article published on May 2011

Advances in exercise, fitness, and performance genomics in 2011.

scientific article published on May 2012

Advances in exercise, fitness, and performance genomics in 2012.

scientific article published on May 2013

Advances in exercise, fitness, and performance genomics in 2013.

scientific article published on January 2014

Advances in exercise, fitness, and performance genomics in 2014.

scientific article published on June 2015

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

scientific article published on 27 May 2016

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study.

scientific article published on 4 April 2012

Anthropometric characteristics of elite female junior rowers

scientific article

Anthropometric characteristics of elite male junior rowers

scientific article published on June 2000

Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities

scientific article

Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: linkage of candidate genes using two sib-pair based variance components analyses

scientific article published in October 2008

Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?

scientific article

Association analyses based on false discovery rate implicate new loci for coronary artery disease

scientific article published on 17 July 2017

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association between FTO variant and change in body weight and its interaction with dietary factors: the DiOGenes study

scientific article published on 23 February 2012

Association between Mediterranean and Nordic diet scores and changes in weight and waist circumference: influence of FTO and TCF7L2 loci

scientific article published on 6 August 2014

Association between birth weight and educational attainment: an individual-based pooled analysis of nine twin cohorts

article

Association between birth weight and visceral fat in adults

scientific article published on 2 June 2010

Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project

scientific article

Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies

scientific article

Association between serotonin 5-HT-2C receptor gene (HTR2C) polymorphisms and obesity- and mental health-related phenotypes in a large population-based cohort

scientific article published on 12 January 2010

Association between the IL6-174G/C SNP and maximally attained lung function

scientific article published on 23 September 2010

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population

scientific article published on 25 February 2009

Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization

scientific article published on 01 January 2020

Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population

scientific article

Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts

scientific article published in PLoS ONE

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

scientific article published on 22 April 2011

Association of genetic predisposition to obesity with type 2 diabetes risk in Han Chinese individuals

scientific article published on 25 June 2014

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

scientific article

Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism

scientific article published in November 2007

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study

scientific article published on 15 June 2009

Associations between Blood Metabolic Profile at 7 Years Old and Eating Disorders in Adolescence: Findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 19 September 2019

Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project.

scientific article published on 12 April 2018

Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans

scientific article published on 05 October 2011

Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study.

scientific article

Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han population

scientific article

Associations of the FTO rs9939609 variant with discrete body fat depots and dietary intake in a multi-ethnic cohort.

scientific article

Beam test results of a Shashlik calorimeter in a high magnetic field

Beam tests of lead tungstate crystal matrices and a silicon strip preshower detector for the CMS electromagnetic calorimeter

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts.

scientific article published on 19 April 2018

Birth weight and blood pressure in young adults: a prospective twin study

scientific article published in October 2001

Birth weight and body composition in young adult men—a prospective twin study

article

Birth weight and body composition in young women: a prospective twin study

scientific article published in April 2002

Birth weight and creatinine clearance in young adult twins: influence of genetic, prenatal, and maternal factors

scientific article published on 8 June 2005

Birthweight in liveborn twins: the influence of the umbilical cord insertion and fusion of placentas

article

Blood pressure in young adulthood and residential greenness in the early-life environment of twins

scientific article

Body composition estimations by BIA versus anthropometric equations in body builders and other power athletes.

scientific article published in March 2002

C-peptide, insulin-like growth factors I and II, and insulin-like growth factor binding protein-1 in cord serum of twins: genetic versus environmental regulation

scientific article published in November 1996

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

CREBRF variant increases obesity risk and protects against diabetes in Samoans.

scientific article published in August 2016

CUBN is a gene locus for albuminuria

scientific article

Calcium intake is associated with adiposity in Black and White men and White women of the HERITAGE Family Study

scientific article published on 01 July 2004

Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.

scientific article

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Changes in genetic and environmental effects on growth during infancy.

scientific article published on 9 November 2011

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Clustering of metabolic risk factors in young adults: genes and environment

scientific article published on February 2008

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population

scientific article published on 17 June 2010

Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31

scientific article published on 27 September 2018

Comment on "A common genetic variant is associated with adult and childhood obesity"

scientific article published on January 2007

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins.

scientific article published on 20 May 2008

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk

scientific article published on 27 March 2012

Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study

scientific article published on 09 September 2009

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response

scientific article published on 20 May 2009

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population

scientific article published on 15 July 2008

Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

scientific article published on 25 June 2009

Common variants in ZNF365 are associated with both mammographic density and breast cancer risk

scientific article

Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans

scientific article published on 01 January 2011

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Complex patterns of direct and indirect association between the transcription Factor-7 like 2 gene, body mass index and type 2 diabetes diagnosis in adulthood in the Hispanic Community Health Study/Study of Latinos

scientific article published on 02 October 2018

Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

scientific article published in 2021

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

scientific article published on 18 March 2012

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals

scientific article

Correction to: Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

scientific article published on 16 October 2017

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies

scientific article

Curves of Placental Weights of Live-Born Twins

article

Curves of placental weights of live-born twins

scientific article published on 01 October 2006

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Determinants of birthweight and intrauterine growth in liveborn twins

article

Determinants of infant growth in four age windows: a twin study

scientific article

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Developments in obesity genetics in the era of genome-wide association studies

scientific article

Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents

scientific article published on 26 February 2015

Dietary factors impact on the association between CTSS variants and obesity related traits

scientific article (publication date: 2012)

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery and replication of several loci significantly associated with lean body mass: a large meta-analysis of genome wide association studies (GWAS) from the 'charge' and 'gefos' consortia

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Disentangling the genetics of lean mass

article

Do genetic factors contribute to the relation between education and metabolic risk factors in young adults? A twin study

scientific article published on 7 December 2012

Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

scientific article

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

scientific article published on 06 March 2019

Eating behavior trajectories in the first 10 years of life and their relationship with BMI

scientific article published on 27 May 2020

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts

scientific article published in October 2017

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

scientific article

Energy and spatial resolution of a Shashlik calorimeter and a silicon preshower detector

Epidemiological study designs to investigate gene-behavior interactions in the context of human obesity

scientific article published on December 2008

Erratum: Corrigendum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

scientific article published in Nature Communications

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article published in July 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations

scientific article published on 30 June 2008

Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples

scientific article published on 20 March 2012

Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight

scientific article published on 20 December 2017

Evidence of interaction between type 2 diabetes susceptibility genes and dietary fat intake for adiposity and glucose homeostasis-related phenotypes

scientific article published in January 2009

Examining the causal association of fasting glucose with blood pressure in healthy children and adolescents: a Mendelian randomization study employing common genetic variants of fasting glucose

scientific article published on 31 July 2014

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

FTO: the first gene contributing to common forms of human obesity

scientific article

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

scientific article

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

From nutrigenomics to personalizing diets: are we ready for precision medicine?

scientific article published on 01 January 2019

GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity

scientific article published on 06 July 2018

Gender mix: does it modify birthweight - outcome association?

article

Gender-specific regional changes in genetic structure of muscularity in early adolescence

scientific article published in June 1997

Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry

scientific article

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

scientific article

Gene-diet interactions on body weight changes.

scientific article

Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE study

scientific article published on 15 June 2018

Genes that make you fat, but keep you healthy

scientific article published on 02 October 2018

Genetic Diversity Turns a New PAGE in Our Understanding of Complex Traits

Genetic analyses of diverse populations improves discovery for complex traits

scientific article published on 19 June 2019

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental causes of tracking in explosive strength during adolescence

scientific article published in September 2005

Genetic and environmental determination of tracking in static strength during adolescence

scientific article published on 2 June 2005

Genetic and environmental determination of tracking in subcutaneous fat distribution during adolescence

scientific article published in September 2007

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODA

scientific article published on 13 July 2016

Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts.

scientific article

Genetic and environmental factors in associations between infant growth and adult cardiometabolic risk profile in twins

scientific article

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.

scientific article published on 14 December 2016

Genetic and environmental influences on blood pressure variability: a study in twins.

scientific article published on April 2013

Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

scientific article published on 23 June 2016

Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education

scientific article published on 14 May 2020

Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts

scientific article published on 29 July 2020

Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

scientific article published on 12 October 2017

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system.

scientific article published on 12 September 2017

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth

scientific article (publication date: 25 May 2010)

Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study

scientific article

Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids

scientific article

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss

scientific article published on 29 May 2013

Genetic predisposition to obesity leads to increased risk of type 2 diabetes

scientific article

Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat.

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies

scientific article

Genetic variance of adolescent growth in stature

scientific article published in March 2000

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

scientific article published on 23 September 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in LIN28B is associated with the timing of puberty

scientific article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetic variation near IRS1 is associated with adiposity and a favorable metabolic profile in U.S. Hispanics/Latinos

scientific article published on 24 September 2016

Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study

scientific article published on 24 May 2019

Genetics of maximally attained lung function: A role for leptin?

article

Genetics: genome-wide risk profiles - will they change your life(style)?

scientific article published on 01 May 2011

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Linkage Scan for the Metabolic Syndrome in the HERITAGE Family Study

scientific article published on 01 December 2003

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

scientific article

Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans

scientific article

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

scientific journal article

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

scientific article published on 27 December 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

scientific article published on 6 February 2017

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

scientific article published on 7 September 2022

Genome-wide association analysis identifies 20 loci that influence adult height

scientific article (publication date: May 2008)

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network

scientific article published on 26 February 2013

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

scientific article

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association study identifies five loci associated with lung function

scientific article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

scientific article

Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).

scientific article published on 17 May 2017

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3

scientific article

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations

scientific article published on 13 October 2018

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

scientific article

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

scientific article published on 21 June 2016

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

scientific article published on 01 October 2018

Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites

scientific article published on 21 May 2008

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

scientific article published in December 2000

Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure

scientific article published on 31 January 2008

Handedness in twins according to zygosity and chorion type: A preliminary report

article

Heritability of objectively assessed daily physical activity and sedentary behavior

scientific article published on 18 September 2013

Heritability of somatotype components from early adolescence into young adulthood: a multivariate analysis on a longitudinal twin study.

scientific article published on July 2003

Heritability of somatotype components: a multivariate analysis

scientific article published on 6 March 2007

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia

scientific article

Identification of a novel percent mammographic density locus at 12q24.

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

scientific article published on 4 September 2017

Identifying typical trajectories in longitudinal data: modelling strategies and interpretations

scientific article published on 05 March 2020

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Influence of SNPs in nutrient-sensitive candidate genes and gene–diet interactions on blood lipids: the DiOGenes study

article

Influence of chorionicity on the heritability estimates of blood pressure: a study in twins

scientific article published in July 2003

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Intake of Total and Subgroups of Fat Minimally Affect the Associations between Selected Single Nucleotide Polymorphisms in the PPARγ Pathway and Changes in Anthropometry among European Adults from Cohorts of the DiOGenes Study.

scientific article

Integrating publicly available genome-wide association data to study the genetic basis of metabolically healthy obese and metabolically obese but normal-weight individuals.

scientific article

Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

scientific article

Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

scientific article published on 5 March 2015

LDL-cholesterol concentrations: a genome-wide association study

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Lack of Evidence for the Role of Human Adenovirus-36 in Obesity in a European Cohort

article by Valère J. Goossens et al published January 2011 in Obesity

Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS).

scientific article published on 4 February 2010

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies

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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

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Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

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scientific article published in The Lancet

Life course variations in the associations between FTO and MC4R gene variants and body size

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Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease

scientific article published on 01 June 2020

Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies

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Loss-of-function mutations in APOC3, triglycerides, and coronary disease

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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

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MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai

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Mammographic breast density and breast cancer: evidence of a shared genetic basis

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Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives

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Melanocortin-4 receptor gene and physical activity in the Québec Family Study

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Mendelian Randomisation Study of Childhood BMI and Early Menarche

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Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease

scientific article published on 27 March 2019

Mendelian randomisation studies of type 2 diabetes: future prospects

scientific article published on February 2008

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

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Meta-analysis and imputation refines the association of 15q25 with smoking quantity

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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

article by Sara Pulit et al published 1 January 2019 in Human Molecular Genetics

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

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Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size

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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

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Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article published on 30 March 2020

Modelling bivariate ordinal responses smoothly with examples from ophthalmology and genetics

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Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk

scientific article published on 8 July 2015

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

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Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study

scientific article published in 2021

Multi-ethnic genome-wide association study for atrial fibrillation

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NIH working group report-using genomic information to guide weight management: From universal to precision treatment

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NOS3 Variants, Physical Activity, and Blood Pressure in the European Youth Heart Study

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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New genetic loci link adipose and insulin biology to body fat distribution

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New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

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No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

scientific article published on 12 October 2016

No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits

scientific article published on 5 May 2010

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

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Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

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Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

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Obesity genomics: assessing the transferability of susceptibility loci across diverse populations

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Obesity – is it a genetic disorder?

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Obesity-susceptibility loci and their influence on adiposity-related traits in transition from adolescence to adulthood--the HUNT study

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Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals

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Obesity: lessons from evolution and the environment

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Observation of a new boson at a mass of 125 GeV with the CMS experiment at the LHC

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PGC-1alpha gene and physical activity in type 2 diabetes mellitus

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PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene x environment interactions in children from the European Youth Heart Study

scientific article published on 29 January 2009

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Parent-of-origin specific linkage and association of the IGF2 gene region with birth weight and adult metabolic risk factors

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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

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Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts

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Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response

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Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene

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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study

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Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

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Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.

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Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

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Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals

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Pleiotropic genes for metabolic syndrome and inflammation

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Polygenic Score for Body Mass Index Is Associated with Disordered Eating in a General Population Cohort

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Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes

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Polymorphisms in the leptin and leptin receptor genes in relation to resting metabolic rate and respiratory quotient in the Québec Family Study.

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Population genetic differentiation of height and body mass index across Europe

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Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification

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Predicting Polygenic Obesity Using Genetic Information

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Progress in the genetics of common obesity and type 2 diabetes

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Progress in the genetics of common obesity: size matters

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Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

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Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

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Quality control and conduct of genome-wide association meta-analyses

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RBP4 variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in Chinese Hans

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Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

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Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.

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Rare and low-frequency coding variants alter human adult height

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

Retrospective Determination of Chorion Type in Twins Using a Simple Questionnaire

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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity

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Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

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Specific genetic influences on nighttime blood pressure

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Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array

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Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity

scientific article published on 28 June 2018

Studies of lead tungstate crystal matrices in high energy beams for the CMS electromagnetic calorimeter at the LHC

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

scientific article published on February 2017

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

scientific article published on 06 April 2007

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

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Testing the role of predicted gene knockouts in human anthropometric trait variation

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The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals

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The CMS experiment at the CERN LHC

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The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

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The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

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The East Flanders Prospective Twin Survey (Belgium): a population–based register

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The Genetic Contribution to Dental Maturation

scientific article published on 01 July 1997

The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

scientific article published on 08 May 2008

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions

scientific article published on 01 January 2018

The bigger picture of FTO: the first GWAS-identified obesity gene

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The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength

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The effect of LRRK2 loss-of-function variants in humans

scientific article published on 27 May 2020

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

scientific article published on 30 March 2020

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The genetic epidemiology of melanocortin 4 receptor variants.

scientific article published on 02 February 2011

The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis

scientific article published in PLoS ONE

The genetics of adiposity.

scientific article published on 9 March 2018

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The influence of maternal BMI and age in twin pregnancies on insulin resistance in the offspring

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The influence of zygosity and chorion type on fat distribution in young adult twins consequences for twin studies.

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The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

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The metabolically healthy overweight and obese and their impact on all-cause mortality.

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The power of genetic diversity in genome-wide association studies of lipids

The prenatal gut microbiome: are we colonized with bacteria in utero?

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The role of country of birth, and genetic and self-identified ancestry, in obesity susceptibility among African and Hispanic Americans

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The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population

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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

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Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis

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Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations.

scientific article published on 9 January 2018

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

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Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.

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Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

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Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

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Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015

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Twin birth weight standards

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Twin studies and estimates of heritability

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Twin-specific intrauterine 'growth' charts based on cross-sectional birthweight data

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Two ethnic-specific polymorphisms in the human Agouti-related protein gene are associated with macronutrient intake

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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

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Variability in the heritability of body mass index: a systematic review and meta-regression

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Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans

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Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans

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Variants in MTNR1B influence fasting glucose levels

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Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population

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Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight

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Whole genome sequence association with E-selectin levels reveals Loss-of-function variant in African Americans

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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

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Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

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