List of works - Giorgio Melloni

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

scientific article

A polygenic risk score predicts atrial fibrillation in cardiovascular disease

scientific article published in 2022

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

scientific article published on 21 March 2014

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.

scientific article published on 13 September 2013

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

scientific article published in Nature Communications

Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease

scientific article published on 13 November 2020

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

scientific article published in Nature Communications

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.

scientific article

Detecting the mutational signature of homologous recombination deficiency in clinical samples

scientific article published on 15 April 2019

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.

scientific article published on 7 May 2015

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

scientific article

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer

scientific article published on 9 February 2016

PATRI, a Genomics Data Integration Tool for Biomarker Discovery

scientific article published on 28 June 2018

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.

scientific article published on 27 December 2016

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

scientific article published on 20 May 2019

The Effect of PCSK9 Inhibition on the Risk of Venous Thromboembolism

scientific article published on 29 March 2020

List of works by Giorgio Melloni

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

A polygenic risk score predicts atrial fibrillation in cardiovascular disease

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups

Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.

Detecting the mutational signature of homologous recombination deficiency in clinical samples

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer

PATRI, a Genomics Data Integration Tool for Biomarker Discovery

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

The Effect of PCSK9 Inhibition on the Risk of Venous Thromboembolism

Very low depth whole genome sequencing in complex trait association studies