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List of works by Nicola Alessio

A rapid, safe, and quantitative in vitro assay for measurement of uracil-DNA glycosylase activity

scientific article published on 01 May 2019

Alterations in the carnitine cycle in a mouse model of Rett syndrome.

scientific article published on 02 February 2017

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells.

scientific article

Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells

scientific article published on 01 March 2019

Crenosoma vulpis in wild and domestic carnivores from Italy: a morphological and molecular study

scientific article published on 25 June 2015

DNA damage and repair in a model of rat vascular injury.

scientific article

De-regulated expression of the BRG1 chromatin remodeling factor in bone marrow mesenchymal stromal cells induces senescence associated with the silencing of NANOG and changes in the levels of chromatin proteins

scientific article

Genes involved in regulation of stem cell properties: studies on their expression in a small cohort of neuroblastoma patients

scientific article

Hybrid complexes of high and low molecular weight hyaluronan delay in vitro replicative senescence of mesenchymal stromal cells: a pilot study for future therapeutic application

scientific article published on 01 July 2018

Impact of histone deacetylase inhibitors SAHA and MS-275 on DNA repair pathways in human mesenchymal stem cells

scientific article published in November 2010

Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes.

scientific article published on 18 January 2017

In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes.

scientific article

Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells

scientific article published on 7 November 2013

Intra-brain microinjection of human mesenchymal stem cells decreases allodynia in neuropathic mice.

scientific article published on 24 November 2009

Irradiation of Mesenchymal Stromal Cells With Low and High Doses of Alpha Particles Induces Senescence and/or Apoptosis.

scientific article published on 2 March 2017

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process.

scientific article published on April 2015

Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage

scientific article published on 18 December 2019

Mesenchymal stromal cells from amniotic fluid are less prone to senescence compared to those obtained from bone marrow: An in vitro study

scientific article published on 15 June 2018

Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy.

scientific article published on 28 April 2016

Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence.

scientific article published on 30 August 2017

Molecular survey of Ehrlichia canis and Coxiella burnetii infections in wild mammals of southern Italy

scientific article published on 17 August 2016

Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity.

scientific article

Neural stem cells from a mouse model of Rett syndrome are prone to senescence, show reduced capacity to cope with genotoxic stress, and are impaired in the differentiation process.

scientific article published on 22 March 2018

New Frontiers in Stem Cell Research and Translational Approaches

scientific article published on 04 January 2020

Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA.

scientific article published on 11 January 2010

Positively charged polymers modulate the fate of human mesenchymal stromal cells via ephrinB2/EphB4 signaling

scientific article

Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors

scientific article published on 10 July 2019

Reduced expression of MECP2 affects cell commitment and maintenance in neurons by triggering senescence: new perspective for Rett syndrome

scientific article

Senescence Phenomena and Metabolic Alteration in Mesenchymal Stromal Cells from a Mouse Model of Rett Syndrome

scientific article published on 21 May 2019

Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation

scientific article

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

scientific article published on 31 January 2013

Stem Cell-Derived Exosomes in Autism Spectrum Disorder

scientific article published on 04 February 2020

Stem Cells and DNA Repair Capacity: Muse Stem Cells Are Among the Best Performers

scientific article published on 01 January 2018

Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cells.

scientific article published on 10 April 2018

The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.

scientific article published on 9 August 2010

The Melanocortin MC5R as a New Target for Treatment of High Glucose-Induced Hypertrophy of the Cardiac H9c2 Cells

scientific article published on 26 October 2018

The secretome of MUSE cells contains factors that may play a role in regulation of stemness, apoptosis and immunomodulation

scientific article

The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

scientific article published on 14 August 2019

Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

scientific article published on 09 June 2016

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