List of works - Vladimir V Sharoyko

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

scientific article published on January 2011

Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.

scientific article

Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells

scientific article published on 19 December 2013

Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment

scientific article published on 21 December 2018

From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction

scientific article published on 26 August 2019

Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion

scientific article

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes

scientific article published on 10 June 2014

Metabolomic analyses reveal profound differences in glycolytic and tricarboxylic acid cycle metabolism in glucose-responsive and -unresponsive clonal β-cell lines

scientific article published on April 2011

Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic beta-cells

scientific article published on 2 November 2005

Novel Formulations of C-Peptide with Long-Acting Therapeutic Potential for Treatment of Diabetic Complications

scientific article published on 11 January 2019

Photosensitive Poly-l-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs

scientific article published on 08 May 2020

Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines

scientific article published on 15 February 2019

Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells

scientific article

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines

scientific article published on 14 July 2006

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration

scientific article

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion

scientific article published on 21 September 2009

Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release

scientific article published in March 2013

Unique and Shared Metabolic Regulation in Clonal β-Cells and Primary Islets Derived From Rat Revealed by Metabolomics Analysis

scientific article published on 16 March 2015

pH-Sensitive Chitosan-Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells

scientific article published on 05 July 2019

List of works by Vladimir V Sharoyko

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.

Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells

Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment

From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction

Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes

Metabolomic analyses reveal profound differences in glycolytic and tricarboxylic acid cycle metabolism in glucose-responsive and -unresponsive clonal β-cell lines

Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic beta-cells

Novel Formulations of C-Peptide with Long-Acting Therapeutic Potential for Treatment of Diabetic Complications

Photosensitive Poly-l-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs

Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines

Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion

Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release

Unique and Shared Metabolic Regulation in Clonal β-Cells and Primary Islets Derived From Rat Revealed by Metabolomics Analysis

pH-Sensitive Chitosan-Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells