List of works - Andriy Yabluchanskiy

A Novel Collagen Matricryptin Reduces Left Ventricular Dilation Post-Myocardial Infarction by Promoting Scar Formation and Angiogenesis

scientific article

Advances and challenges in geroscience research: An update

scientific article published on 01 December 2018

Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies

scientific article published on 03 August 2018

Age-related alterations in gait function in freely moving male C57BL/6 mice: translational relevance of decreased cadence and increased gait variability

scientific article published on 01 August 2019

Age-related decline in peripheral vascular health predicts cognitive impairment.

scientific article published on 27 April 2019

Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults

scientific article published on 17 June 2019

Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction.

scientific article

CORM-3, a carbon monoxide-releasing molecule, alters the inflammatory response and reduces brain damage in a rat model of hemorrhagic stroke

scientific article published in February 2012

Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction.

scientific article

Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice

scientific article published on 01 April 2019

Cerebral blood flow alteration following acute myocardial infarction in mice

scientific article published on 05 September 2018

Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.

scientific article

Cerebrovascular responses to graded exercise in young healthy males and females

scientific article published on 01 October 2020

Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research

scientific article published on 29 April 2019

Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle.

scientific article

Connective tissue growth factor (CTGF) in age-related vascular pathologies.

scientific article

Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.

scientific article

Cyp2c44-mediated decrease of 15-HETE exacerbates pulmonary hypertension.

scientific article published on 16 June 2017

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.

scientific article

Deriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence.

scientific article published on 15 April 2015

Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice

scientific article published on 11 March 2016

Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality

scientific article published on 01 February 2019

Heavy hitting: Using water to label humans

scientific article

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.

scientific article

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.

scientific article published on 29 June 2017

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.

scientific article

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.

scientific article

IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation.

scientific article published on 24 April 2017

Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype

scientific article

Is Isolated Systolic Hypertension Worse Than Combined Systolic/Diastolic Hypertension? ⬇️

scientific article published on October 9, 2012

Left ventricular remodeling: one small step for the extracellular matrix will translate to a giant leap for the myocardium.

scientific article published on 25 January 2013

Macrophage overexpression of matrix metalloproteinase-9 in aged mice improves diastolic physiology and cardiac wound healing after myocardial infarction

scientific article

Matrix Metalloproteinases: Drug Targets for Myocardial Infarction ⬇️

scientific article published on March 1, 2013

Matrix metalloproteinase-9: Many shades of function in cardiovascular disease.

scientific article

Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.

scientific article published on 15 April 2015

Neutrophil roles in left ventricular remodeling following myocardial infarction.

scientific article published on 03 June 2013

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

article

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

scientific article published on 01 June 2018

Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

scientific article published on 23 November 2018

Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.

scientific article published in February 2019

Proteomic Analysis of the Left Ventricle Post-myocardial Infarction to Identify In Vivo Candidate Matrix Metalloproteinase Substrates ⬇️

scientific article published on January 1, 2013

Relationship between leukocyte kinetics and behavioral tests changes in the inflammatory process of hemorrhagic stroke recovery

scientific article published on 13 October 2010

Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults

scientific article published on 04 October 2018

Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

scientific article published on 08 March 2019

Role of endothelial NAD+ deficiency in age-related vascular dysfunction

scientific article published on 15 March 2019

Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction

scientific article published on 18 June 2018

Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain

scientific article published on 31 January 2022

Syndecan-4: a novel regulator of collagen synthesis and deposition in the pressure-overloaded myocardium.

scientific article published on 25 March 2015

Temporal neutrophil polarization following myocardial infarction

scientific article published on 29 January 2016

The Mouse Heart Attack Research Tool 1.0 database

scientific article published on 18 May 2018

The circular relationship between matrix metalloproteinase-9 and inflammation following myocardial infarction

scientific article (publication date: August 2015)

Thrombospondin-1: the good, the bad, and the complicated

scientific article published in December 2013

Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition.

scientific article published on August 2015

Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis.

scientific article published on 23 December 2016

Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.

scientific article published on 6 February 2018

Using plasma matrix metalloproteinase-9 and monocyte chemoattractant protein-1 to predict future cardiovascular events in subjects with carotid atherosclerosis

scientific article

List of works by Andriy Yabluchanskiy

A Novel Collagen Matricryptin Reduces Left Ventricular Dilation Post-Myocardial Infarction by Promoting Scar Formation and Angiogenesis

Advances and challenges in geroscience research: An update

Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies

Age-related alterations in gait function in freely moving male C57BL/6 mice: translational relevance of decreased cadence and increased gait variability

Age-related decline in peripheral vascular health predicts cognitive impairment.

Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults

Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction.

CORM-3, a carbon monoxide-releasing molecule, alters the inflammatory response and reduces brain damage in a rat model of hemorrhagic stroke

Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction.

Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice

Cerebral blood flow alteration following acute myocardial infarction in mice

Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.

Cerebrovascular responses to graded exercise in young healthy males and females

Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research

Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle.

Connective tissue growth factor (CTGF) in age-related vascular pathologies.

Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.

Cyp2c44-mediated decrease of 15-HETE exacerbates pulmonary hypertension.

Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.

Deriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence.

Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice

Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality

Heavy hitting: Using water to label humans

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease.

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.

IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation.

Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype

Is Isolated Systolic Hypertension Worse Than Combined Systolic/Diastolic Hypertension? ⬇️

Left ventricular remodeling: one small step for the extracellular matrix will translate to a giant leap for the myocardium.

Macrophage overexpression of matrix metalloproteinase-9 in aged mice improves diastolic physiology and cardiac wound healing after myocardial infarction

Matrix Metalloproteinases: Drug Targets for Myocardial Infarction ⬇️

Matrix metalloproteinase-9: Many shades of function in cardiovascular disease.

Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.

Neutrophil roles in left ventricular remodeling following myocardial infarction.

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.

Proteomic Analysis of the Left Ventricle Post-myocardial Infarction to Identify In Vivo Candidate Matrix Metalloproteinase Substrates ⬇️

Relationship between leukocyte kinetics and behavioral tests changes in the inflammatory process of hemorrhagic stroke recovery

Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults

Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

Role of endothelial NAD+ deficiency in age-related vascular dysfunction

Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction

Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain

Syndecan-4: a novel regulator of collagen synthesis and deposition in the pressure-overloaded myocardium.

Temporal neutrophil polarization following myocardial infarction

The Mouse Heart Attack Research Tool 1.0 database

The circular relationship between matrix metalloproteinase-9 and inflammation following myocardial infarction

Thrombospondin-1: the good, the bad, and the complicated

Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition.

Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis.

Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.

Using plasma matrix metalloproteinase-9 and monocyte chemoattractant protein-1 to predict future cardiovascular events in subjects with carotid atherosclerosis