List of works - Adolfo Sadile

A classical Mendelian cross-breeding study of the Naples high and low excitability rat lines.

scientific article

A morphometric evidence for a hyperfunctioning mesolimbic system in an animal model of ADHD.

scientific article published in March 2002

A quantitative cytochrome oxidase mapping study, cross-regional and neurobehavioural correlations in the anterior forebrain of an animal model of Attention Deficit Hyperactivity Disorder.

scientific article published on July 1998

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice

scientific journal article

Adrenergic receptor systems and unscheduled DNA synthesis in the rat brain

scientific article published on 01 January 1995

Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels.

scientific article published in November 2002

Antidepressants share the ability to increase catecholamine output in the bed nucleus of stria terminalis: a possible role in antidepressant therapy?

scientific article

Behavioral habituation to spatial novelty: interference and noninterference studies.

scientific article

Brain RNA synthesis, long-term potentiation and depression at the perforant path-granule cell synapse in the guinea pig.

scientific article published in January 1995

Clinical, Experimental, and Modeling Studies in AD/HD.

scientific article published in January 2004

Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, acetylcholine esterase levels in the striatum, and cAMP response element-binding protein levels in the striatum and piriform cortex.

scientific article published on 20 February 2008

Differential alcohol drinking behaviour and dependence in the Naples low- and high-excitability rat lines.

scientific article published on 18 May 2006

Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats.

scientific article

Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder.

scientific article published on November 2003

Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.

scientific article

Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.

scientific article published on 2 December 2013

Environmental factors during postnatal period modify activity and non-selective attention in the Naples High-Excitability rat.

scientific article published in March 2002

Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.

scientific article published on 12 November 2008

Galactosilated dopamine increases attention without reducing activity in C57BL/6 mice.

scientific article published on 13 October 2007

Histamine H1 receptor knockout mice exhibit impaired spatial memory in the eight-arm radial maze.

scientific article published on May 2009

Immediate early genes and brain DNA remodeling in the Naples high- and low-excitability rat lines following exposure to a spatial novelty.

scientific article published in January 1995

Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum.

scientific article published on 17 January 2015

Impaired metabolic capacity in the perirhinal and posterior parietal cortex lead to dissociation between attentional, motivational and spatial components of exploration in the Naples High-Excitability rat.

scientific article

In memoriam Terje Sagvolden

scientific article

Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats that feature the mesocortical variant of ADHD.

scientific article

Long-term habituation to spatial novelty modifies posttrial synchronized sleep in rats.

scientific article published in January 1993

Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats.

scientific article published on January 2014

NMDA and non-NMDA sensitive [L-3H]glutamate receptor binding in the brain of the Naples high- and low-excitability rats: an autoradiographic study.

scientific article published in August 1996

Network operations revealed by brain metabolic mapping in a genetic model of hyperactivity and attention deficit: the naples high- and low-excitability rats.

scientific article published in January 2000

Neurobehavioral adaptations to methylphenidate: The issue of early adolescent exposure ⬇️

scientific article published on March 2, 2011

Neuronal histamine and the interplay of memory, reinforcement and emotions.

scientific article published on 08 January 2010

Non-selective attention and nitric oxide in putative animal models of Attention-Deficit Hyperactivity Disorder ⬇️

scientific article published on September 1, 1998

Non-selective attention in a rat model of hyperactivity and attention deficit: subchronic methylphenydate and nitric oxide synthesis inhibitor treatment

scientific article published on 01 January 2000

Prenatal elevation of endocannabinoids corrects the unbalance between dopamine systems and reduces activity in the Naples High Excitability rats.

scientific article published on January 2003

Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

scientific article

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.

scientific article

Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples high-excitability rats.

scientific article published on 13 February 2010

Reduced transduction mechanisms in the anterior accumbal interface of an animal model of Attention-Deficit Hyperactivity Disorder.

scientific article published on July 1998

Selective inhibition of neuronal nitric oxide synthesis reduces hyperactivity and increases non-selective attention in the Naples High-Excitability rat.

scientific article published in March 2002

Strain-specific correlations between hippocampal structural traits and habituation in a spatial novelty situation.

scientific article published in May 1987

The Naples High- and Low-Excitability rats: selective breeding, behavioral profile, morphometry, and molecular biology of the mesocortical dopamine system.

scientific article

The dorsal noradrenergic bundle modulates DNA remodeling in the rat brain upon exposure to a spatial novelty.

scientific article published in January 1995

Transcription factor expression, RNA synthesis and NADPH-diaphorase across the rat brain and exposure to spatial novelty.

scientific article published on 30 June 2007

Unscheduled brain DNA synthesis, long-term potentiation, and depression at the perforant path-granule cell synapse in the rat

scientific article published on 01 January 1995

List of works by Adolfo Sadile

A classical Mendelian cross-breeding study of the Naples high and low excitability rat lines.

A morphometric evidence for a hyperfunctioning mesolimbic system in an animal model of ADHD.

A quantitative cytochrome oxidase mapping study, cross-regional and neurobehavioural correlations in the anterior forebrain of an animal model of Attention Deficit Hyperactivity Disorder.

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice

Adrenergic receptor systems and unscheduled DNA synthesis in the rat brain

Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels.

Antidepressants share the ability to increase catecholamine output in the bed nucleus of stria terminalis: a possible role in antidepressant therapy?

Behavioral habituation to spatial novelty: interference and noninterference studies.

Brain RNA synthesis, long-term potentiation and depression at the perforant path-granule cell synapse in the guinea pig.

Clinical, Experimental, and Modeling Studies in AD/HD.

Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, acetylcholine esterase levels in the striatum, and cAMP response element-binding protein levels in the striatum and piriform cortex.

Differential alcohol drinking behaviour and dependence in the Naples low- and high-excitability rat lines.

Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats.

Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder.

Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.

Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.

Environmental factors during postnatal period modify activity and non-selective attention in the Naples High-Excitability rat.

Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.

Galactosilated dopamine increases attention without reducing activity in C57BL/6 mice.

Histamine H1 receptor knockout mice exhibit impaired spatial memory in the eight-arm radial maze.

Immediate early genes and brain DNA remodeling in the Naples high- and low-excitability rat lines following exposure to a spatial novelty.

Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum.

Impaired metabolic capacity in the perirhinal and posterior parietal cortex lead to dissociation between attentional, motivational and spatial components of exploration in the Naples High-Excitability rat.

In memoriam Terje Sagvolden

Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats that feature the mesocortical variant of ADHD.

Long-term habituation to spatial novelty modifies posttrial synchronized sleep in rats.

Modulatory effects following subchronic stimulation of brain 5-HT7-R system in mice and rats.

NMDA and non-NMDA sensitive [L-3H]glutamate receptor binding in the brain of the Naples high- and low-excitability rats: an autoradiographic study.

Network operations revealed by brain metabolic mapping in a genetic model of hyperactivity and attention deficit: the naples high- and low-excitability rats.

Neurobehavioral adaptations to methylphenidate: The issue of early adolescent exposure ⬇️

Neuronal histamine and the interplay of memory, reinforcement and emotions.

Non-selective attention and nitric oxide in putative animal models of Attention-Deficit Hyperactivity Disorder ⬇️

Non-selective attention in a rat model of hyperactivity and attention deficit: subchronic methylphenydate and nitric oxide synthesis inhibitor treatment

Prenatal elevation of endocannabinoids corrects the unbalance between dopamine systems and reduces activity in the Naples High Excitability rats.

Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.

Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples high-excitability rats.

Reduced transduction mechanisms in the anterior accumbal interface of an animal model of Attention-Deficit Hyperactivity Disorder.

Selective inhibition of neuronal nitric oxide synthesis reduces hyperactivity and increases non-selective attention in the Naples High-Excitability rat.

Strain-specific correlations between hippocampal structural traits and habituation in a spatial novelty situation.

The Naples High- and Low-Excitability rats: selective breeding, behavioral profile, morphometry, and molecular biology of the mesocortical dopamine system.

The dorsal noradrenergic bundle modulates DNA remodeling in the rat brain upon exposure to a spatial novelty.

Transcription factor expression, RNA synthesis and NADPH-diaphorase across the rat brain and exposure to spatial novelty.

Unscheduled brain DNA synthesis, long-term potentiation, and depression at the perforant path-granule cell synapse in the rat