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List of works by Dick Chan

A comparative analysis of phenotypic predictors of mutations in familial hypercholesterolemia.

scientific article published on 2 February 2018

A genetic risk score predicts coronary artery disease in familial hypercholesterolaemia: enhancing the precision of risk assessment

scientific article published on 09 October 2019

A randomized trial of the effect of statin and fibrate therapy on arterial function in CKD.

scientific article

ATP-binding cassette transporter G8 gene as a determinant of apolipoprotein B-100 kinetics in overweight men.

scientific article

Adipocytokines and VLDL metabolism: independent regulatory effects of adiponectin, insulin resistance, and fat compartments on VLDL apolipoprotein B-100 kinetics?

scientific article published in March 2005

Adipose tissue compartments and insulin resistance in overweight-obese Caucasian men

scientific article published on 01 February 2004

Adipose tissue compartments and the kinetics of very-low-density lipoprotein apolipoprotein B-100 in non-obese men.

scientific article published in September 2002

An age-matched computed tomography angiographic study of coronary atherosclerotic plaques in patients with familial hypercholesterolaemia

scientific article published on 06 March 2020

Angiographic progression of coronary atherosclerosis in patients with familial hypercholesterolaemia treated with non-statin therapy: Impact of a fat-modified diet and a resin

scientific article

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity

scientific article published on 2 February 2016

Apolipoprotein B-100 and apoA-II kinetics as determinants of cellular cholesterol efflux

scientific article published on 28 June 2012

Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: Effect of fenofibrate treatment

scientific article published on 26 January 2012

Apolipoprotein(a) Kinetics in Statin-Treated Patients With Elevated Plasma Lipoprotein(a) Concentration

scientific article published on 01 December 2019

Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.

scientific article published on 12 January 2006

Association between skeletal muscle fat content and very-low-density lipoprotein-apolipoprotein B-100 transport in obesity: effect of weight loss

scientific article published on 29 May 2014

Association of Plasma Ceramides and Sphingomyelin With VLDL apoB-100 Fractional Catabolic Rate Before and After Rosuvastatin Treatment

scientific article published on 27 March 2015

Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia.

scientific article

Association of apolipoprotein M with high-density lipoprotein kinetics in overweight-obese men.

scientific article published on 22 November 2009

Atorvastatin and fenofibrate have comparable effects on VLDL-apolipoprotein C-III kinetics in men with the metabolic syndrome.

scientific article published on 19 June 2008

Atorvastatin plus omega-3 fatty acid ethyl ester decreases very-low-density lipoprotein triglyceride production in insulin resistant obese men.

scientific article published on 29 December 2013

Comparative Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition and Statins on Postprandial Triglyceride-Rich Lipoprotein Metabolism

scientific article published on 07 June 2018

Comparative aspects of the care of familial hypercholesterolemia in the "Ten Countries Study"

scientific article published on 25 January 2019

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

scientific article published on 01 July 2018

Critical review of non-statin treatments for dyslipoproteinemia.

scientific article published on 10 February 2014

Demystifying the management of hypertriglyceridaemia.

scientific article

Dose-dependent effect of rosuvastatin on VLDL-apolipoprotein C-III kinetics in the metabolic syndrome

scientific article published on 28 May 2008

Dose-dependent effect of rosuvastatin on apolipoprotein B-100 kinetics in the metabolic syndrome

scientific article published on 09 April 2007

Dose-dependent effects of rosuvastatin on the plasma sphingolipidome and phospholipidome in the metabolic syndrome

scientific article published on 20 August 2014

Effect of Lipoprotein(a) on the Diagnosis of Familial Hypercholesterolemia: Does It Make a Difference in the Clinic?

scientific article published on 15 July 2019

Effect of a statin on hepatic apolipoprotein B-100 secretion and plasma campesterol levels in the metabolic syndrome

scientific article published on 01 July 2003

Effect of atorvastatin on apolipoprotein B48 metabolism and low-density lipoprotein receptor activity in normolipidemic patients with coronary artery disease.

scientific article published in October 2003

Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet

scientific article

Effect of laparoscopic sleeve gastrectomy on elevated C-reactive protein and atherogenic dyslipidemia in morbidly obese patients

scientific article published on 15 December 2010

Effect of niacin on high-density lipoprotein apolipoprotein A-I kinetics in statin-treated patients with type 2 diabetes mellitus.

scientific article published on 27 November 2013

Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetes.

scientific article published on 18 December 2015

Effect of omega-3 fatty acid supplementation on arterial elasticity in patients with familial hypercholesterolaemia on statin therapy.

scientific article published on 3 August 2016

Effect of weight loss on HDL-apoA-II kinetics in the metabolic syndrome.

scientific article published on 02 October 2009

Effect of weight loss on LDL and HDL kinetics in the metabolic syndrome: associations with changes in plasma retinol-binding protein-4 and adiponectin levels.

scientific article published on 8 August 2007

Effect of weight loss on postprandial lipemia and low-density lipoprotein receptor binding in overweight men.

scientific article published in February 2003

Effect of ω-3 fatty acid ethyl esters on apolipoprotein B-48 kinetics in obese subjects on a weight-loss diet: a new tracer kinetic study in the postprandial state.

scientific article published on 27 February 2014

Effects of atorvastatin and n-3 fatty acid supplementation on VLDL apolipoprotein C-III kinetics in men with abdominal obesity

scientific article published on 24 February 2010

Effects of extended-release niacin on the postprandial metabolism of Lp(a) and ApoB-100-containing lipoproteins in statin-treated men with type 2 diabetes mellitus

scientific article published on 29 October 2015

Elevated lipoprotein(a), hypertension and renal insufficiency as predictors of coronary artery disease in patients with genetically confirmed heterozygous familial hypercholesterolemia.

scientific article published on 21 August 2015

Factorial Effects of Evolocumab and Atorvastatin on Lipoprotein Metabolism

scientific article published on 09 December 2016

Factorial study of the effect of n-3 fatty acid supplementation and atorvastatin on the kinetics of HDL apolipoproteins A-I and A-II in men with abdominal obesity

scientific article published on 01 July 2006

Familial Hypercholesterolaemia and Lipoprotein(a) Phenotypes in a Community-Based Cohort: Associations with Carotid Intima-Media Thickness, Focal Plaque and Cardiovascular Outcomes

Familial combined hyperlipidemia and hyperlipoprotein(a) as phenotypic mimics of familial hypercholesterolemia: Frequencies, associations and predictions.

scientific article published on 26 August 2016

Fat compartments and apolipoprotein B-100 kinetics in overweight-obese men.

scientific article published in January 2003

Fish oils, phytosterols and weight loss in the regulation of lipoprotein transport in the metabolic syndrome: lessons from stable isotope tracer studies.

scientific article published on September 2006

Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentration

scientific article published on 14 April 2019

High-density lipoprotein (HDL) transport in the metabolic syndrome: application of a new model for HDL particle kinetics

scientific article published on 20 December 2005

High-density lipoprotein apolipoprotein A-I kinetics: comparison of radioactive and stable isotope studies

scientific article published on 01 September 2006

Insulin resistance, inflammation, and blood pressure determine vascular dysfunction in CKD.

scientific article published on December 2006

Inter-relationships between proprotein convertase subtilisin/kexin type 9, apolipoprotein C-III and plasma apolipoprotein B-48 transport in obese subjects: a stable isotope study in the postprandial state.

scientific article published in March 2015

Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study

scientific article published on 31 July 2014

LDL heterogeneity revisited: lesson for the metabolic syndrome from a new interpopulation study?

scientific article published on 01 November 2004

Lipoprotein (a) and Low-density lipoprotein apolipoprotein B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery disease

scientific article published on 13 December 2018

Lipoprotein kinetics in the metabolic syndrome: pathophysiological and therapeutic lessons from stable isotope studies

scientific article published on February 2004

Lipoprotein transport in the metabolic syndrome: methodological aspects of stable isotope kinetic studies.

scientific article published in September 2004

Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol-Lowering Therapy

scientific article published on 01 April 2019

Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity

scientific article

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

scientific article published on 2 October 2015

More data needed on curcuminoids in hypertriglyceridaemia.

scientific article published on 7 January 2014

NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

scientific article published in July 2005

Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity

scientific article published on 11 February 2010

Nutrition and metabolism: new studies of the effects of diets and exercise on lipid and lipoprotein metabolism

scientific article published on 01 February 2010

Of mice and men: blowing away the cobwebs from the mechanism of action of niacin on HDL metabolism.

scientific article

Origin and therapy for hypertriglyceridaemia in type 2 diabetes

scientific article

Oxidized LDL and small LDL particle size are independently predictive of a selective defect in microcirculatory endothelial function in type 2 diabetes

scientific article (publication date: September 2005)

PCSK9 Inhibition with alirocumab increases the catabolism of lipoprotein(a) particles in statin-treated patients with elevated lipoprotein(a)

scientific article published on 30 March 2020

Pathogenesis and management of the diabetogenic effect of statins: a role for adiponectin and coenzyme Q10?

scientific article

Pharmacological regulation of dyslipoproteinaemia in insulin resistant states

scientific article published on 01 January 2008

Plasma Proprotein Convertase Subtilisin Kexin Type 9 as a Predictor of Carotid Atherosclerosis in Asymptomatic Adults.

scientific article published on 18 November 2015

Plasma apolipoprotein B-48 transport in obese men: a new tracer kinetic study in the postprandial state.

scientific article published on 20 December 2013

Plasma apolipoprotein C-III transport in centrally obese men: associations with very low-density lipoprotein apolipoprotein B and high-density lipoprotein apolipoprotein A-I metabolism.

scientific article

Plasma markers of cholesterol homeostasis and apolipoprotein B-100 kinetics in the metabolic syndrome.

scientific article published in April 2003

Plasma markers of cholesterol homeostasis in metabolic syndrome subjects with or without type-2 diabetes.

scientific article published in July 2009

Plasma phospholipid transfer protein activity, a determinant of HDL kinetics in vivo

scientific article published on 01 December 2006

Postprandial hypertriglyceridemia and cardiovascular disease: current and future therapies.

scientific article published on March 2013

Postprandial lipoprotein metabolism in familial hypercholesterolemia: thinking outside the box ⬇️

scientific article published on September 25, 2011

Randomized controlled trial of the effect of n-3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron remnants in men with visceral obesity.

scientific article published in February 2003

Recent explanatory trials of the mode of action of drug therapies on lipoprotein metabolism.

scientific article

Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia.

scientific article published in August 2002

Regulatory effects of fenofibrate and atorvastatin on lipoprotein A-I and lipoprotein A-I:A-II kinetics in the metabolic syndrome.

scientific article published on 03 August 2009

Response by Watts et al to Letter Regarding Article, "Factorial Effects of Evolocumab and Atorvastatin on Lipoprotein Metabolism"

scientific article published on 01 July 2017

Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuria.

scientific article

The Knowns and Unknowns of Contemporary Statin Therapy for Familial Hypercholesterolemia

scientific article published on 01 September 2020

The effect of fenofibrate on HDL cholesterol and HDL particle concentration in postmenopausal women on tibolone therapy.

scientific article published in October 2010

The metabolic and pharmacologic bases for treating atherogenic dyslipidaemia

scientific article published on 09 October 2013

Thematic review series: patient-oriented research. Design and analysis of lipoprotein tracer kinetics studies in humans.

scientific article

Therapeutic regulation of apoB100 metabolism in insulin resistance in vivo.

scientific article published on 31 May 2009

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III.

scientific article published on 5 July 2016

Use of Intralipid for kinetic analysis of HDL apoC-III: evidence for a homogeneous kinetic pool of apoC-III in plasma

scientific article published on 23 March 2006

Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.

scientific article published in July 2008

Waist circumference, waist-to-hip ratio and body mass index as predictors of adipose tissue compartments in men

scientific article published on 01 June 2003

ω-3 Fatty Acid Ethyl Esters Diminish Postprandial Lipemia in Familial Hypercholesterolemia

scientific article published on 4 August 2016

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