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List of works by Olivier Cuvillier

1H and 13C-NMR assignments for sialylated oligosaccharide-alditols related to mucins. Study of thirteen components from hen ovomucin and swallow nest mucin

scientific article published on January 1, 1992

Acetaminophen induces a caspase-dependent and Bcl-XL sensitive apoptosis in human hepatoma cells and lymphocytes.

scientific article

Biochemical methods for quantifying sphingolipids: ceramide, sphingosine, sphingosine kinase-1 activity, and sphingosine-1-phosphate.

scientific article

Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis.

scientific article

Cationic and Neutral N-Heterocyclic Carbene Gold(I) Complexes: Cytotoxicity, NCI-60 screening, Cellular Uptake, Inhibition of Mammalian Thioredoxin Reductase and ROS formation.

scientific article published on 30 March 2018

Ceramide in apoptosis: a revisited role.

scientific article

Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models.

scientific article

Differential effects of free and liposome-associated 1-O-octadecyl-2-O-methylglycerophosphocholine on protein kinase C.

scientific article published on July 1999

Downregulating sphingosine kinase-1 for cancer therapy

scientific article published on 01 August 2008

Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival ⬇️

scientific article published on July 13, 1998

FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model.

scientific article published on 9 August 2016

FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1.

scientific article published on 19 October 2010

First evidence of human meconium glycoasparagines

scientific article published on 01 May 1995

First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer.

scientific article

Gem GTPase acts upstream Gmip/RhoA to regulate cortical actin remodeling and spindle positioning during early mitosis.

scientific article published on 30 August 2014

Glutathione peroxidase-1 protects from CD95-induced apoptosis

scientific article

Hypoxia, Therapeutic Resistance, and Sphingosine 1-Phosphate

scientific article published on January 1, 2013

Hypoxia-inducible factors and sphingosine 1-phosphate signaling.

scientific article

Increased phospholipase D activity contributes to tumorigenesis in prostate cancer cell models

scientific article published on 14 July 2020

Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties

scientific article published on 15 March 2012

Inhibition of the GTPase Rac1 mediates the antimigratory effects of metformin in prostate cancer cells.

scientific article published on 19 December 2014

Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

scientific article published on 01 May 2000

Mechanisms of castration resistance: Intratumoral hypoxia stimulates the androgen receptor expression

scientific article published on 16 February 2016

N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

scientific article published on September 1998

Novel synergistic mechanism for sst2 somatostatin and TNFalpha receptors to induce apoptosis: crosstalk between NF-kappaB and JNK pathways.

scientific article published on 28 April 2006

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells.

scientific article published on 13 April 2014

Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis

scientific journal article

Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells

scientific article

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease

scientific article published on 27 January 2014

Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria ⬇️

scientific article published on November 1, 2001

Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

scientific article published on 01 January 1998

Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression.

scientific article published on 28 March 2017

Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells.

scientific article published in February 2001

Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.

scientific article

Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.

scientific article published on October 2008

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

scientific article

Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival

scientific article

Sphingosine kinase-1--a potential therapeutic target in cancer.

scientific article published on February 2007

Sphingosine‐1‐Phosphate in Cell Growth and Cell Deatha ⬇️

scientific article published on June 19, 1998

Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1.

scientific article

Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands.

scientific article

The sphingosine kinase-1 survival pathway is a molecular target for the tumor-suppressive tea and wine polyphenols in prostate cancer.

scientific article published on 3 June 2010

The therapeutic potential of HIF-2 antagonism in renal cell carcinoma

scientific article published on February 2017

When the sphingosine kinase 1/sphingosine 1-phosphate pathway meets hypoxia signaling: new targets for cancer therapy.

scientific article published on 21 April 2009

[Erratum to "Mechanisms of castration resistance: Intratumoral hypoxia stimulates the androgen receptor expression" [Prog. Urol. 26 (3) (2016) 159-167]]

scientific article published on 01 June 2016

[Multiple sclerosis and immuno-modulators of sphingosine 1-phosphate receptors]

scientific article published on 31 March 2020

[SphingomabTM, an anti-sphingosine 1-phosphate antibody to inhibit hypoxia]

scientific article published on 17 November 2015

[Sphingosine 1-phosphate as a biomarker for Alzheimer's disease?]

scientific article published on 01 May 2014

[Sphingosine 1-phosphate receptors: from biology to physiopathology]

scientific article published on 12 November 2012

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