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List of works by Frédéric Bost

"Double hit" makes the difference.

scientific article published on 9 August 2012

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

scientific article

Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans

scientific article published on 16 March 2010

Co-culture of human fibroblasts, smooth muscle and endothelial cells promotes osteopontin induction in hypoxia

scientific article published on 07 February 2020

Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.

scientific article

Editorial: Metformin: Beyond Diabetes

scientific article published on 06 December 2019

Effect of maternal hyperglycemia on NaK ATPase activity in fetal rat kidney

scientific article published on 01 January 1993

Energy disruptors: rising stars in anticancer therapy?

scientific article

Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC

scientific article published on 23 November 2020

Frequency and prognostic evaluation of 3p21-22 allelic losses in non-small-cell lung cancer

scientific article published on 01 December 1995

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage

scientific article

Human inter-alpha-trypsin inhibitor: full-length cDNA sequence of the heavy chain H1

scientific article (publication date: 17 August 1992)

Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence

scientific article

Hypoxia decreases insulin signaling pathways in adipocytes

scientific article

Hypoxia protects against the cell death triggered by oxovanadium-galactomannan complexes in HepG2 cells

scientific article published on 22 March 2019

Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients

scientific article published on 03 February 2020

Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.

scientific article published on 20 March 2017

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

scientific article published on 19 October 2020

Implication of MAP kinases in obesity-induced inflammation and insulin resistance

scientific article published on 8 September 2014

Inhibition of the GTPase Rac1 mediates the antimigratory effects of metformin in prostate cancer cells.

scientific article published on 19 December 2014

Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes

scientific article

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

scientific article published on 28 September 2016

Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.

scientific article published on 23 February 2017

Metformin and cancer therapy.

scientific article published on January 2012

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

scientific article

Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration.

scientific article published on 28 May 2014

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

scientific article published on 3 May 2011

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells

scientific article

Metformin: a metabolic disruptor and anti-diabetic drug to target human leukemia

scientific article published on 22 January 2014

Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.

scientific article

New perspectives for metformin in cancer therapy

scientific article published on 12 April 2013

PGC-1α inhibits polyamine synthesis to suppress prostate cancer aggressiveness

scientific article published on 07 May 2019

Prevention of mutagenesis: new potential mechanisms of metformin action in neoplastic cells

scientific article published on 01 April 2012

Primary Cilium in Cancer Hallmarks ⬇️

scientific article published on 16 March 2019

Protein N-glycosylation alteration and glycolysis inhibition both contribute to the antiproliferative action of 2-deoxyglucose in breast cancer cells

scientific article published on 03 July 2018

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.

scientific article published on February 2002

Role of MAPKs in development and differentiation: lessons from knockout mice.

scientific article published on 27 June 2006

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

scientific article published on 14 December 2012

Sirtuin 7: a new marker of aggressiveness in prostate cancer

scientific article

Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes

scientific article

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

scientific article published on 9 March 2010

The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

scientific article published on December 1997

The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells

scientific article

The Lac repressor provides a reversible gene expression system in undifferentiated and differentiated embryonic stem cell.

scientific article published on July 2005

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

scientific article published on 21 January 2008

The combination of metformin and 2 deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells

scientific article published on 01 July 2010

The defective transforming phenotype of c-Jun Ala(63/73) is rescued by mutation of the C-terminal phosphorylation site.

scientific article

The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.

scientific article

The metabolic modulator PGC-1α in cancer

scientific article published on 01 February 2019

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

scientific article published on 21 April 2013

The role of MAPKs in adipocyte differentiation and obesity.

scientific article

UBTD1 is a mechano-regulator controlling cancer aggressiveness

scientific article published on 25 February 2019

[Obesity, diabetes and insulin resistance. Alterations of insulin signalling]

scientific article published on 01 January 2006

c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.

scientific article published on August 2000

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