List of works - John A Wemmie

ASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury

scientific article

ASIC1A in neurons is critical for fear-related behaviors.

scientific article

ASIC1A in the bed nucleus of the stria terminalis mediates TMT-evoked freezing.

scientific article published on 21 July 2015

ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons

scientific article published on 22 January 2003

Acid-sensing ion channel 1: a novel therapeutic target for migraine with aura.

scientific article published in October 2012

Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.

scholarly article

Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior

scientific article published on April 2009

Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice.

scientific article published on 11 December 2013

Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.

scientific article

Acid-sensing ion channels in pain and disease.

scientific article

Acid-sensing ion channels: advances, questions and therapeutic opportunities.

scientific article published on 7 August 2006

Alterations of the cerebellum and basal ganglia in bipolar disorder mood states detected by quantitative T1ρ mapping.

scientific article published on 7 January 2018

Amygdala volume correlates positively with fearfulness in normal healthy girls

scientific article

Attenuation of cocaine seeking in rats via enhancement of infralimbic cortical activity using stable step-function opsins

scientific article published on 12 July 2018

Brain abnormalities in bipolar disorder detected by quantitative T1ρ mapping

scientific article

Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation.

scientific article published in July 2015

Ca2+-Binding Protein 1 Regulates Hippocampal-dependent Memory and Synaptic Plasticity.

scientific article published on 13 April 2018

Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1.

scientific article

Detecting activity-evoked pH changes in human brain

scientific article

Drug abuse and the simplest neurotransmitter

scientific article

Eccentricity mapping of the human visual cortex to evaluate temporal dynamics of functional T1ρ mapping

scientific article

Evaluation of activity-dependent functional pH and T1ρ response in the visual cortex

scientific article published on 31 January 2014

Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning

scientific article

Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity after Unreinforced Lever Presses.

scientific article

Fear and panic in humans with bilateral amygdala damage

scientific article

Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.

scientific article

Functional properties of an isolated alpha beta heterodimeric human placenta insulin-like growth factor 1 receptor complex

scientific article published on 01 May 1988

Functional t1ρ imaging in panic disorder

scientific article published on 21 October 2013

Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons

scientific journal article

Impaired motor performance and learning in glia maturation factor-knockout mice

scientific journal article

Impaired sensory processing measured by functional MRI in Bipolar disorder manic and depressed mood states

scientific article published on 3 July 2017

Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.

scientific article

Mutations in prickle orthologs cause seizures in flies, mice, and humans

scientific article

Neonatal leptin administration alters regional brain volumes and blocks neonatal growth restriction-induced behavioral and cardiovascular dysfunction in male mice

scientific article

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

scientific article

Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior

scientific article

PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders

scientific article

Peripheral inflammation during abnormal mood states in bipolar I disorder

scientific article

Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala

scientific article

Quantitative T1ρ mapping links the cerebellum and lithium use in bipolar disorder

scientific article

R1ρ sensitivity to pH and other compounds at clinically accessible spin-lock fields in the presence of proteins

scientific article published on 19 November 2019

Rapid acquisition strategy for functional T1ρ mapping of the brain

scientific article

Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.

scientific article published on 13 January 2014

Relationship altered between functional T1ρ and BOLD signals in bipolar disorder.

scientific article published on 14 September 2017

Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

scientific article

Seizure termination by acidosis depends on ASIC1a

scientific article published on 8 June 2008

Stereotactic atlas-based depth electrode localization in the human amygdala.

scientific article published on 26 June 2009

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

scientific journal article

T1ρ imaging in premanifest Huntington disease reveals changes associated with disease progression

scientific article

Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit.

scientific article published on 30 July 2007

The Saccharomyces cerevisiae AP-1 protein discriminates between oxidative stress elicited by the oxidants H2O2 and diamide

scientific article published on 01 March 1997

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

scientific article

The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.

scientific article

The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis.

scientific article

The cytoskeletal protein alpha-actinin regulates acid-sensing ion channel 1a through a C-terminal interaction.

scientific article

The endogenous functional turkey erythrocyte and rat liver insulin receptor is an alpha 2 beta 2 heterotetrameric complex.

scientific article published on October 1990

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

scientific article published in December 2004

The non-canonical Wnt ligand Wnt5a rescues morphological deficits in Prickle2-deficient hippocampal neurons.

scientific article published in October 2013

Transient acidosis while retrieving a fear-related memory enhances its lability.

scientific article

cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1

scientific article

List of works by John A Wemmie

ASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury

ASIC1A in neurons is critical for fear-related behaviors.

ASIC1A in the bed nucleus of the stria terminalis mediates TMT-evoked freezing.

ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons

Acid-sensing ion channel 1: a novel therapeutic target for migraine with aura.

Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.

Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior

Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice.

Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.

Acid-sensing ion channels in pain and disease.

Acid-sensing ion channels: advances, questions and therapeutic opportunities.

Alterations of the cerebellum and basal ganglia in bipolar disorder mood states detected by quantitative T1ρ mapping.

Amygdala volume correlates positively with fearfulness in normal healthy girls

Attenuation of cocaine seeking in rats via enhancement of infralimbic cortical activity using stable step-function opsins

Brain abnormalities in bipolar disorder detected by quantitative T1ρ mapping

Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation.

Ca2+-Binding Protein 1 Regulates Hippocampal-dependent Memory and Synaptic Plasticity.

Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1.

Detecting activity-evoked pH changes in human brain

Drug abuse and the simplest neurotransmitter

Eccentricity mapping of the human visual cortex to evaluate temporal dynamics of functional T1ρ mapping

Evaluation of activity-dependent functional pH and T1ρ response in the visual cortex

Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning

Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity after Unreinforced Lever Presses.

Fear and panic in humans with bilateral amygdala damage

Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.

Functional properties of an isolated alpha beta heterodimeric human placenta insulin-like growth factor 1 receptor complex

Functional t1ρ imaging in panic disorder

Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons

Impaired motor performance and learning in glia maturation factor-knockout mice

Impaired sensory processing measured by functional MRI in Bipolar disorder manic and depressed mood states

Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.

Mutations in prickle orthologs cause seizures in flies, mice, and humans

Neonatal leptin administration alters regional brain volumes and blocks neonatal growth restriction-induced behavioral and cardiovascular dysfunction in male mice

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior

PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders

Peripheral inflammation during abnormal mood states in bipolar I disorder

Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala

Quantitative T1ρ mapping links the cerebellum and lithium use in bipolar disorder

R1ρ sensitivity to pH and other compounds at clinically accessible spin-lock fields in the presence of proteins

Rapid acquisition strategy for functional T1ρ mapping of the brain

Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.

Relationship altered between functional T1ρ and BOLD signals in bipolar disorder.

Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

Seizure termination by acidosis depends on ASIC1a

Stereotactic atlas-based depth electrode localization in the human amygdala.

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

T1ρ imaging in premanifest Huntington disease reveals changes associated with disease progression

Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit.

The Saccharomyces cerevisiae AP-1 protein discriminates between oxidative stress elicited by the oxidants H2O2 and diamide

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory

The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.

The bed nucleus of the stria terminalis is critical for anxiety-related behavior evoked by CO2 and acidosis.

The cytoskeletal protein alpha-actinin regulates acid-sensing ion channel 1a through a C-terminal interaction.

The endogenous functional turkey erythrocyte and rat liver insulin receptor is an alpha 2 beta 2 heterotetrameric complex.

The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.

The non-canonical Wnt ligand Wnt5a rescues morphological deficits in Prickle2-deficient hippocampal neurons.

Transient acidosis while retrieving a fear-related memory enhances its lability.

cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1