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List of works by Charles Harrington

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

scientific article published in January 2017

Absence of Abnormal Hyperphosphorylation of Tau in Intracellular Tangles in Alzheimerʼs Disease

scientific article published on September 1, 1995

Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease

scientific article published on 8 April 2016

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

scientific article published on 24 November 2017

Aluminosilicate particulate and β-amyloid in vitro interactions: a model of Alzheimer plaque formation

scientific article published on August 1, 1998

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking.

scientific article published on 15 September 2017

Alzheimer's disease. A glycation connection.

scientific article published in July 1994

Assays for the Screening and Characterization of Tau Aggregation Inhibitors.

scientific article published in January 2017

Biosynthesis of wall teichoic acids in Staphylococcus aureus H, Micrococcus varians and Bacillus subtilis W23. Involvement of lipid intermediates containing the disaccharide N-acetylmannosaminyl N-acetylglucosamine.

scientific article published on December 1985

Calcyclin binding protein and Siah-1 interacting protein in Alzheimer's disease pathology: neuronal localization and possible function

scientific article published on 20 December 2012

Characterisation of an Antibody Relevant to the Neuropathology of Alzheimer Disease

scientific article published on January 1, 1995

Characterisation of an epitope specific to the neuron-specific isoform of human enolase recognised by a monoclonal antibody raised against a synthetic peptide corresponding to the C-terminus of β/A4-protein

scientific article published on October 3, 1993

Competitive ELISA for the measurement of tau protein in Alzheimer's disease

scientific article published on December 5, 1990

Complex Disposition of Methylthioninium Redox Forms Determines Efficacy in Tau Aggregation Inhibitor Therapy for Alzheimer's Disease

scientific article

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia

scientific article published on 30 October 2020

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.

scientific article

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

article

Evolution of a homopurine–homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene

scientific article published on December 19, 1997

Examination of the validity of the hierarchical model of neuropathological staging in normal aging and Alzheimer's disease.

scientific article

Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains

scientific article published in 2021

Lack of an association of estrogen receptor alpha gene polymorphisms and transcriptional activity with Alzheimer disease

scientific article published on 01 February 2000

Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe.

scientific article published on 16 December 2009

Measurement of distinct immunochemical presentations of tau protein in Alzheimer disease.

scientific article published on July 1991

Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine.

scientific article

Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development

scientific article published on 8 December 2017

Monoaminergic neuropathology in Alzheimer's disease

scientific article published on 12 April 2016

Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders

scientific article published on 01 April 2000

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

scientific article published on 17 November 2017

Presence of axonal paired helical filament-tau in Alzheimer's disease: submicroscopic localization.

scientific article published in August 1994

Presence of the apolipoprotein E type epsilon 4 allele is not associated with neurofibrillary pathology or biochemical changes to tau protein.

scientific article published in September 1997

Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease

scientific article published on 01 January 1997

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

scientific article

Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease.

scientific article published in January 1996

Stripline resonator and preamplifier for preclinical magnetic resonance imaging at 4.7 T.

scientific article published on 4 August 2011

Susceptibility Genetics in the Etiopathogenesis of Alzheimer's Disease: Role for Potential Confounding Factors

scientific article published on 01 September 1997

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies

scientific article

Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease

scientific article

Tau-aggregation inhibitor therapy for Alzheimer's disease

scientific article

The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies.

scientific article published in February 2000

The Molecular Pathology of Alzheimer's Disease

scientific article published on 01 February 2012

The relationship between clinical dementia and neuropathological staging (Braak) in a very elderly community sample

scientific article published on 01 January 1996

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

scientific article

Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints.

scientific article published on 23 September 2008

What is the molecular pathology that underlies hippocampal memory decline?

scientific article published in July 2009