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List of works by Nicholas T Crump

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

scientific article published on 25 November 2021

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

scientific article published on 31 March 2022

BET inhibition disrupts transcription but retains enhancer-promoter contact

scientific article published on 11 January 2021

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

scientific article published on 26 June 2019

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

scientific article published on 05 August 2019

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP

scientific article

H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

scientific article published on 02 April 2020

Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition

scientific article

Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome.

scientific article published on 27 July 2008

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

scientific article

Why are so many MLL lysine methyltransferases required for normal mammalian development?

scientific article published on 16 May 2019