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List of works by Edgar Pick

A Cys-Gly-Cys triad in the dehydrogenase region of Nox2 plays a key role in the interaction with p67phox

scientific article published on 9 July 2015

A simple method for the production of migration inhibitory factor by concanavalin A-stimulated lymphocytes ⬇️

scientific article published on January 1, 1977

Absolute and Relative Activity Values in Assessing the Effect of NADPH Oxidase Inhibitors.

scientific article published on 13 November 2015

Activation of macrophage adenylate cyclase by stimulants of the oxidative burst and by arachidonic acid—Two distinct mechanisms ⬇️

scientific article published on June 1, 1981

Activation of the Superoxide-Generating NADPH Oxidase by Chimeric Proteins Consisting of Segments of the Cytosolic Component p67phoxand the Small GTPase Rac1 ⬇️

scientific article published on December 4, 2001

Assembly of the phagocyte NADPH oxidase complex: chimeric constructs derived from the cytosolic components as tools for exploring structure-function relationships

scientific article

Cell-free NADPH oxidase activation assays: "in vitro veritas".

scientific article published on January 2014

Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b.

scientific article published on 16 November 2007

Cyclic GMP metabolism in macrophages. I. Regulation of cyclic GMP levels by calcium and stimulation of cyclic GMP synthesis by NO-generating agents

scientific article published on 01 June 1980

Cytoskeletal control of concanavalin A receptor mobility in peritoneal macrophages ⬇️

scientific article published on January 1, 1979

Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras

scientific article published on 3 February 2004

Editorial: When charge is in charge--"Millikan" for leukocyte biologists

scientific article published on 01 April 2010

Enhancement of macrophage adenylate cyclase by microtubule disrupting drugs ⬇️

scientific article published on December 1, 1978

Epitope identification for human neutrophil flavocytochrome b monoclonals 48 and 449.

scientific article

Facilitation of adenylate cyclase stimulation in macrophages by lectins ⬇️

scientific article published on July 1, 1979

Fibrin-clot Formation by Extracts of Rabbit-skin Homografts

scientific article published in Nature

G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction

scientific article

Generation of superoxide by purified and relipidated cytochrome b559 in the absence of cytosolic activators

scientific article published on 01 July 1993

Glucosylation and ADP ribosylation of rho proteins: effects on nucleotide binding, GTPase activity, and effector coupling

scientific article published on 01 April 1998

Inhibition of NADPH oxidase activation by peptides mapping within the dehydrogenase region of Nox2-A “peptide walking” study ⬇️

scientific article published on December 19, 2011

Intracellular mediation of lymphokine action: mimicry of migration inhibitory factor (MIF) action by phorbol myristate acetate (PMA) and the ionophore A23187 ⬇️

scientific article published on January 1, 1979

Macrophage-mediated cytolysis off erythrocytes in the guinea pig. I. Activation by stimulators of the oxidative burst

scientific article published on 01 July 1981

Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".

scientific article

Mapping of functional domains in the p22(phox) subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking"

scientific article

Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex

scientific article (publication date: 28 August 2001)

Mutational Analysis of Novel Effector Domains in Rac1 Involved in the Activation of Nicotinamide Adenine Dinucleotide Phosphate (Reduced) Oxidase ⬇️

scientific article published on May 19, 1998

Nonlymphoid cells interacted with mitogens fail to elaborate macrophage migration inhibitory factor (MIF) ⬇️

scientific article published on March 15, 1978

Nucleotide binding properties of cytosolic components required for expression of activity of the superoxide generating NADPH oxidase

scientific article published on 01 March 1990

Opening the black box: lessons from cell-free systems on the phagocyte NADPH-oxidase

scientific article published on 12 March 2007

Passive Agglutination Tests: Bismuth Tannate Test

scientific article published in Nature

Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader ⬇️

scientific article published on January 1, 1981

Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

scientific article published on February 2012

Release of Skin Reactive Factor from Guinea-pig Lymphocytes by Mitogens ⬇️

scientific article published on January 17, 1970

Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task

scientific article published on 05 March 2014

Role of the rac1 p21-GDP-dissociation inhibitor for rho heterodimer in the activation of the superoxide-forming NADPH oxidase of macrophages

scientific article

Role of transmethylation in the elicitation of an oxidative burst in macrophages ⬇️

scientific article published on September 15, 1982

Strategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or "all that you did and did not want to know about Nox inhibitory peptides".

scientific article published on 06 May 2012

Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages--induction by multiple nonphagocytic stimuli.

scientific article

Superoxide production by cytochrome b559. Mechanism of cytosol-independent activation

scientific article published on 01 February 1994

Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly

scientific article published on 01 December 2000

The cytosolic component p47(phox) is not a sine qua non participant in the activation of NADPH oxidase but is required for optimal superoxide production

scientific article published on 01 November 1996

The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes".

scientific article published on 9 December 2002

The mechanism of action of lymphokines. VII. Modulation of the action of macrophage migration inhibitory factor by antioxidants and drugs affecting thromboxane synthesis.

scientific article published on October 1983

The mechanism of action of soluble lymphocytic mediators. II. Modification of macrophage migration and migration inhibitory factor action by drugs, enzymes and cationic environment

scientific article published on 01 March 1974

Tripartite chimeras comprising functional domains derived from the cytosolic NADPH oxidase components p47phox, p67phox, and Rac1 elicit activator-independent superoxide production by phagocyte membranes: an essential role for anionic membrane phosph

scientific article

Unsaturated fatty acids as second messengers of superoxide generation by macrophages ⬇️

scientific article published on July 15, 1983

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages ⬇️

scientific article published on October 1, 1984

p67phox -derived self-assembled peptides prevent Nox2 NADPH oxidase activation by an auto-inhibitory mechanism

scientific article published on 08 July 2020

p67phox binds to a newly identified site in Nox2 following the disengagement of an intramolecular bond-Canaan sighted?

scientific article published on 22 January 2020

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