List of works - Elena Ribe

A role for APP in Wnt signalling links synapse loss with β-amyloid production

scientific article published on 20 September 2018

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice

scientific article published on 24 August 2005

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. ⬇️

scientific article

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

scientific article published on October 2013

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.

scientific article

Caspase-2: vestigial remnant or master regulator?

scientific article published on 23 September 2008

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons

scientific article published on 25 July 2018

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

scientific article

Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP Tg2576 mice

scientific article published on 01 October 2004

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development.

scientific article published on 8 May 2019

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

scientific article published on 11 July 2005

Insulin signalling in Alzheimer's disease and diabetes: from epidemiology to molecular links.

scientific article

Mechanisms of neuronal death in disease: defining the models and the players.

scientific article published on October 2008

NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

scientific article

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

scientific article

The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice

scientific article (publication date: 10 February 2011)

List of works by Elena Ribe

A role for APP in Wnt signalling links synapse loss with β-amyloid production

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. ⬇️

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.

Caspase-2: vestigial remnant or master regulator?

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP Tg2576 mice

Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development.

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

Insulin signalling in Alzheimer's disease and diabetes: from epidemiology to molecular links.

Mechanisms of neuronal death in disease: defining the models and the players.

NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice