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List of works by Christopher I Slape

A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement.

scientific article

Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition.

scientific article published on April 2007

Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma ⬇️

scientific article published on June 21, 2012

EphA3 biology and cancer.

scientific article

Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome.

scientific article published on 04 July 2008

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

scientific article

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model

scientific article published on 8 February 2012

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

scientific article published on 26 September 2011

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.

scientific article

OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1

scientific article

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.

scientific article

Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.

scientific article published on June 2007

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins

scientific article published on 21 September 2013

The role of NUP98 gene fusions in hematologic malignancy

scientific article

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