List of works - Valeri Zakhartchenko

3D structured illumination microscopy of mammalian embryos and spermatozoa

scientific article

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

scientific journal article

A decade of experience with genetically tailored pig models for diabetes and metabolic research

scientific article published on 26 August 2020

A porcine model of familial adenomatous polyposis

scientific article published in August 2012

Bovine somatic cell nuclear transfer using recipient oocytes recovered by ovum pick-up: effect of maternal lineage of oocyte donors

scientific article

Cell-Mediated Transgenesis in Rabbits: Chimeric and Nuclear Transfer Animals

article by Valeri Zakhartchenko et al published 13 October 2010 in Biology of Reproduction

Changes of higher order chromatin arrangements during major genome activation in bovine preimplantation embryos

scientific article

Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing

scientific article

Coenzyme Q(10) in submicron-sized dispersion improves development, hatching, cell proliferation, and adenosine triphosphate content of in vitro-produced bovine embryos.

scientific article published in August 1999

Composition of parental mitochondrial DNA in cloned bovine embryos.

scientific article

Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos

scientific article

Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

scientific article published in January 2003

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus

scientific article

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

scientific article

Effects of high concentrations of hyaluronan in culture medium on development and survival rates of fresh and frozen-thawed bovine embryos produced in vitro.

scientific article published in July 2002

Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts.

scientific article published in March 1999

Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.

scientific article published on July 2003

Epigenetic reprogramming in mammalian nuclear transfer

scientific article

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

scientific article

FISH on 3D preserved bovine and murine preimplantation embryos.

scientific article published in January 2010

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

scientific article

Fine mapping of genome activation in bovine embryos by RNA sequencing

scientific article published on 03 March 2014

Formation of nucleoli in interspecies nuclear transfer embryos derived from bovine, porcine, and rabbit oocytes and nuclear donor cells of various species

scientific article published on 14 January 2011

Generation of transgenic cattle by lentiviral gene transfer into oocytes

scientific article published on 24 March 2004

Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments

scientific article published on 06 June 2014

Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies

scientific article published on 25 November 2020

Heteroplasmy in bovine fetuses produced by intra- and inter-subspecific somatic cell nuclear transfer: neutral segregation of nuclear donor mitochondrial DNA in various tissues and evidence for recipient cow mitochondria in fetal blood

scientific article published in January 2003

Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs

scientific article

Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos

scientific article published on 19 March 2003

Intracytoplasmic sperm injection in bovine: effects of oocyte activation, sperm pretreatment and injection technique

scientific article published in October 2000

Manipulating the Epigenome in Nuclear Transfer Cloning: Where, When and How ⬇️

scientific article published on 28 December 2020

Maternal-Fetal Transplacental Leakage of Mitochondrial DNA in Bovine Nuclear Transfer Pregnancies: Potential Implications for Offspring and Recipients

Methylation reprogramming and chromosomal aneuploidy in in vivo fertilized and cloned rabbit preimplantation embryos

scientific article published on 17 March 2004

Mitochondria and the success of somatic cell nuclear transfer cloning: from nuclear-mitochondrial interactions to mitochondrial complementation and mitochondrial DNA recombination

scientific article

Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

Non-balanced mix of mitochondrial DNA in cloned cattle produced by cytoplast-blastomere fusion.

scientific article published in April 1998

Nuclear architecture in developmental biology and cell specialisation.

scientific article published in January 2011

Nuclear transfer in cattle with non-transfected and transfected fetal or cloned transgenic fetal and postnatal fibroblasts

scientific article published in 2001

Nuclear transfer in mammals: recent developments and future perspectives.

scientific article

Nuclear-cytoplasmic interactions affect in utero developmental capacity, phenotype, and cellular metabolism of bovine nuclear transfer fetuses

scientific article published on 17 December 2003

Nucleolar protein allocation and ultrastructure in bovine embryos produced by nuclear transfer from embryonic cells

scientific article

Nucleolar proteins and ultrastructure in bovine in vivo developed, in vitro produced, and parthenogenetic cleavage-stage embryos

scientific article

Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos

scientific article published on January 2014

Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig.

scientific article

Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle

scientific article published in April 2010

Quantitation of retroviral-mediated transfer using luciferase in living and lysed cells.

scientific article

Quantitative monitoring of pluripotency gene activation after somatic cloning in cattle

scientific article published on 21 February 2007

Rabbit somatic cell cloning: effects of donor cell type, histone acetylation status and chimeric embryo complementation

scientific article published in January 2007

Reduced amino acids in the bovine uterine lumen of cloned versus in vitro fertilized pregnancies prior to implantation

scientific article

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs

scientific article published on January 2014

Remodeling of donor nuclei, DNA-synthesis, and ploidy of bovine cumulus cell nuclear transfer embryos: effect of activation protocol.

scientific article published in August 2001

Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications

scientific article (publication date: 2015)

Reprogramming of active and repressive histone modifications following nuclear transfer with rabbit mesenchymal stem cells and adult fibroblasts.

scientific article

Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes of in vitro fertilized embryos

scientific article

Secretion of interferon-tau by bovine embryos in long-term culture: comparison of in vivo derived, in vitro produced, nuclear transfer and demi-embryos.

scientific article published in April 1999

Stage-dependent remodeling of the nuclear envelope and lamina during rabbit early embryonic development

scientific article published on 4 December 2015

Support for the development of bovine embryos in vitro by secretions of bovine trophoblastic vesicles derived in vitro

article

The effect of activation of Mammalian oocytes on remodeling of donor nuclei after nuclear transfer

scientific article published in January 2002

The endometrium responds differently to cloned versus fertilized embryos

scholarly article

Tissue-specific elevated genomic cytosine methylation levels are associated with an overgrowth phenotype of bovine fetuses derived by in vitro techniques

scientific article published on 17 March 2004

Ultra-Structural Alterations in In Vitro Produced Four-Cell Bovine Embryos Following Controlled Slow Freezing or Vitrification.

scientific article published on 21 August 2015

Viable pigs with a conditionally-activated oncogenic KRAS mutation.

scientific article published on 26 February 2015

[Application of stem cell technology and nuclear transfer in animal models]

scientific article published on 01 July 2002

List of works by Valeri Zakhartchenko

3D structured illumination microscopy of mammalian embryos and spermatozoa

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

A decade of experience with genetically tailored pig models for diabetes and metabolic research

A porcine model of familial adenomatous polyposis

Bovine somatic cell nuclear transfer using recipient oocytes recovered by ovum pick-up: effect of maternal lineage of oocyte donors

Cell-Mediated Transgenesis in Rabbits: Chimeric and Nuclear Transfer Animals

Changes of higher order chromatin arrangements during major genome activation in bovine preimplantation embryos

Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing

Coenzyme Q(10) in submicron-sized dispersion improves development, hatching, cell proliferation, and adenosine triphosphate content of in vitro-produced bovine embryos.

Composition of parental mitochondrial DNA in cloned bovine embryos.

Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos

Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

Effects of high concentrations of hyaluronan in culture medium on development and survival rates of fresh and frozen-thawed bovine embryos produced in vitro.

Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts.

Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.

Epigenetic reprogramming in mammalian nuclear transfer

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

FISH on 3D preserved bovine and murine preimplantation embryos.

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

Fine mapping of genome activation in bovine embryos by RNA sequencing

Formation of nucleoli in interspecies nuclear transfer embryos derived from bovine, porcine, and rabbit oocytes and nuclear donor cells of various species

Generation of transgenic cattle by lentiviral gene transfer into oocytes

Genome activation in bovine embryos: review of the literature and new insights from RNA sequencing experiments

Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies

Heteroplasmy in bovine fetuses produced by intra- and inter-subspecific somatic cell nuclear transfer: neutral segregation of nuclear donor mitochondrial DNA in various tissues and evidence for recipient cow mitochondria in fetal blood

Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs

Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos

Intracytoplasmic sperm injection in bovine: effects of oocyte activation, sperm pretreatment and injection technique

Manipulating the Epigenome in Nuclear Transfer Cloning: Where, When and How ⬇️

Maternal-Fetal Transplacental Leakage of Mitochondrial DNA in Bovine Nuclear Transfer Pregnancies: Potential Implications for Offspring and Recipients

Methylation reprogramming and chromosomal aneuploidy in in vivo fertilized and cloned rabbit preimplantation embryos

Mitochondria and the success of somatic cell nuclear transfer cloning: from nuclear-mitochondrial interactions to mitochondrial complementation and mitochondrial DNA recombination

Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning

Non-balanced mix of mitochondrial DNA in cloned cattle produced by cytoplast-blastomere fusion.

Nuclear architecture in developmental biology and cell specialisation.

Nuclear transfer in cattle with non-transfected and transfected fetal or cloned transgenic fetal and postnatal fibroblasts

Nuclear transfer in mammals: recent developments and future perspectives.

Nuclear-cytoplasmic interactions affect in utero developmental capacity, phenotype, and cellular metabolism of bovine nuclear transfer fetuses

Nucleolar protein allocation and ultrastructure in bovine embryos produced by nuclear transfer from embryonic cells

Nucleolar proteins and ultrastructure in bovine in vivo developed, in vitro produced, and parthenogenetic cleavage-stage embryos

Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos

Potential of primary kidney cells for somatic cell nuclear transfer mediated transgenesis in pig.

Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle

Quantitation of retroviral-mediated transfer using luciferase in living and lysed cells.

Quantitative monitoring of pluripotency gene activation after somatic cloning in cattle

Rabbit somatic cell cloning: effects of donor cell type, histone acetylation status and chimeric embryo complementation

Reduced amino acids in the bovine uterine lumen of cloned versus in vitro fertilized pregnancies prior to implantation

Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs

Remodeling of donor nuclei, DNA-synthesis, and ploidy of bovine cumulus cell nuclear transfer embryos: effect of activation protocol.

Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications

Reprogramming of active and repressive histone modifications following nuclear transfer with rabbit mesenchymal stem cells and adult fibroblasts.

Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes of in vitro fertilized embryos

Secretion of interferon-tau by bovine embryos in long-term culture: comparison of in vivo derived, in vitro produced, nuclear transfer and demi-embryos.

Stage-dependent remodeling of the nuclear envelope and lamina during rabbit early embryonic development

Support for the development of bovine embryos in vitro by secretions of bovine trophoblastic vesicles derived in vitro

The effect of activation of Mammalian oocytes on remodeling of donor nuclei after nuclear transfer

The endometrium responds differently to cloned versus fertilized embryos

Tissue-specific elevated genomic cytosine methylation levels are associated with an overgrowth phenotype of bovine fetuses derived by in vitro techniques

Ultra-Structural Alterations in In Vitro Produced Four-Cell Bovine Embryos Following Controlled Slow Freezing or Vitrification.

Viable pigs with a conditionally-activated oncogenic KRAS mutation.

[Application of stem cell technology and nuclear transfer in animal models]