Search filters

List of works by Rusli Ismail

(2E)-2-Benzyl-idene-5,6-dimethoxy-indan-1-one

scientific article published on 11 September 2010

(E)-2-(3,4-Dimeth-oxy-benzyl-idene)-5,6-dimeth-oxy-2,3-dihydro-1H-inden-1-one

scientific article published on 20 October 2010

(E)-2-(3-Chloro-benzyl-idene)-5,6-dimeth-oxy-2,3-dihydro-1H-inden-1-one

scientific article published on 20 October 2010

(E)-2-(4-Bromo-benzyl-idene)indan-1-one

scientific article published on 11 August 2011

(E)-2-[4-(Piperidin-1-yl)benzyl-idene]-2,3-dihydro-1H-inden-1-one

scientific article published on 20 October 2010

(E)-2-[4-(Trifluoro-meth-oxy)benzyl-idene]indan-1-one

scientific article published on 30 July 2011

(E)-5,6-Dimeth-oxy-2-(pyridin-4-yl-methyl-idene)-2,3-dihydro-1H-inden-1-one.

scientific article published on 9 October 2010

2-[(E)-4-(Dimethyl-amino)-benzyl-idene]indan-1-one

scientific article published on 9 July 2011

4'-(4-Bromo-phen-yl)-1'-methyl-dispiro-[indan-2,2'-pyrrolidine-3',2''-indan]-1,3,1''-trione

scientific article published on 29 October 2011

4'-[5-(4-Fluoro-phen-yl)pyridin-3-yl]-1'-methyl-dispiro-[indan-2,2'-pyrrolidine-3',2''-indan]-1,3,1''-trione.

scientific article published on 27 August 2011

5,6-Dimeth-oxy-4',5'-diphenyl-indane-2-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-1,2''-dione

scientific article published on 11 September 2010

7'-[4-(Trifluoro-meth-yl)phen-yl]-5',6',7',7a'-tetra-hydrodispiro-[indan-2,5'-pyrrolo-[1,2-c][1,3]thia-zole-6',2''-indan]-1,3,1''-trione.

scientific article published on 12 November 2011

A facile three-component [3+2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines acting as antimycobacterial agents

scientific article published on 4 January 2013

A facile three-component [3+2]-cycloaddition/annulation domino protocol for the regio- and diastereoselective synthesis of novel penta- and hexacyclic cage systems, involving the generation of two heterocyclic rings and five contiguous stereocenters

scientific article published in April 2011

A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of new-fangled dispiropyrrolothiazoles as antimycobacterial agents

scientific article published on 22 October 2012

A simple method for the detection of CYP2C9 polymorphisms: nested allele-specific multiplex polymerase chain reaction

scientific article published in October 2003

ABCB1 Polymorphisms and Cold Pressor Pain Responses: Opioid-Dependent Patients on Methadone Maintenance Therapy

scientific article

AChE inhibitor : A regio- and stereo-selective 1,3-dipolar cycloaddition for the synthesis of novel substituted 5,6-dimethoxy spiro[5.3′]-oxindole-spiro-[6.3″]-2,3-dihydro-1H-inden-1″-one-7-(substituted aryl)-tetrahydro-1H-pyrrolo[1,2-c][1,3]th

scientific article published in January 2012

Acute Oral Toxicity and Brine Shrimp Lethality of Methanol Extract of Mentha Spicata L (Lamiaceae)

scientific article published on 13 February 2014

An improved rapid genotyping method for the study of beta-2 adrenergic receptor gene polymorphisms using single tube allele specific multiplex PCR.

scientific article

Antimycobacterial Activity: Synthesis and Biological Evaluation of Novel Substituted (3E,5E)-3,5-diarylidene-1-phenethylpiperidine-4-one Derivatives

scientific article published in April 2013

Antimycobacterial Agents: Synthesis and Biological Evaluation of Novel 4-(Substituted-phenyl)-6-methyl-2-oxo-N-(pyridin-2-yl)-1,2,3,4-tetrahydropyrimidine- 5-carboxamide Derivatives by Using One-pot Multicomponent Method

scientific article published in December 2012

Antimycobacterial activity: a facile three-component [3+2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines

scientific article published on 21 June 2012

Antimycobacterial activity: synthesis of novel 3-(substituted phenyl)-6,7-dimethoxy-3a,4-dihydro-3H-indeno[1,2-c]isoxazole analogues

scientific article published on 30 June 2011

Antituberculosis: synthesis and antimycobacterial activity of novel benzimidazole derivatives

scientific article published on 5 December 2013

Better retention of Malaysian opiate dependents treated with high dose methadone in methadone maintenance therapy

scientific article published on 17 December 2010

CYP2A6 polymorphisms in Malays, Chinese and Indians.

scientific article

CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study

scientific article published on 10 August 2016

Correlation of tramadol pharmacokinetics and CYP2D6*10 genotype in Malaysian subjects.

scientific article published in September 2002

Corrigendum to: A facile three-component [3+2]-cycloaddition/annulation domino protocol for the regio- and diastereoselective synthesis of novel penta- and hexacyclic cage systems, involving the generation of two heterocyclic rings and five contiguou

scientific article published in May 2012

Discovery of novel methanone derivatives acting as antimycobacterial agents

scientific article published on 14 March 2011

Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro

scientific article published on 24 July 2013

Estimation of population pharmacokinetics for carbamazepine in Malaysian patients using the OPT® computer program

scientific article published in February 1993

Ethnic differences in response to non-selective b-blockade among racial groups in Malaysia

scientific article published in May 2000

Ethyl 1-[2-(morpholin-4-yl)eth-yl]-2-[4-(morpholin-4-yl)phen-yl]-1H-1,3-benzimidazole-5-carboxyl-ate. ⬇️

scientific article published on 22 June 2011

Facile, regio- and diastereoselective synthesis of spiro-pyrrolidine and pyrrolizine derivatives and evaluation of their antiproliferative activities.

scientific article published on 10 July 2014

Functional characterization of cytochrome P450 2A6 allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22.

scientific article published on 5 February 2010

Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity.

scientific article published in January 2008

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians.

scientific article

Genetic polymorphism of CYP2D6 in Chinese subjects in Malaysia.

scientific article

Genetic polymorphism of CYP2D6 in patients with cardiovascular disease -- a cohort study.

scientific article published in December 2004

Genetic polymorphism of CYP2D6: Malaysian Indians have the highest frequency for CYP2D6*4 in Asia

scientific article published in October 2001

Genetic variations in loci relevant to natural killer cell function are affected by ethnicity but are generally not correlated with susceptibility to HIV-1.

scientific article published on 2 February 2012

Haplotypes frequencies of CYP2B6 in Malaysia

scientific article published in October 2012

Heterogeneity of the CYP2D6 gene among Malays in Malaysia

scientific article published in June 2001

Heterologous Expression of Human Cytochromes P450 2D6 and CYP3A4 in Escherichia coli and Their Functional Characterization ⬇️

scientific article published on December 1, 2011

Homogeneous FRET immunoassays for use in personalized medicine

scientific article published in June 2014

Hypersensitivity reactions to high-dose co-trimoxazole in HIV-infected Malaysian and Scottish patients

scientific article published in September 1999

Impact of Opioid Receptor, Mu 1 (OPRM1) Polymorphisms on Pain Sensitivity and Clinical Response to Opioid Analgesic Therapy

scientific article published in March 2013

In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability.

scientific article published on 17 May 2013

In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities ⬇️

scientific article published on March 3, 2011

In vitro effects of active constituents and extracts of Orthosiphon stamineus on the activities of three major human cDNA-expressed cytochrome P450 enzymes ⬇️

scientific article published on January 27, 2011

In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity

scientific article published in July 2010

In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19) ⬇️

scientific article published on November 18, 2010

In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8).

scientific article published on 4 February 2012

In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica

scientific article published on 8 May 2010

In-vitro inhibitory effect of Tualang honey on cytochrome P450 2C8 activity

scientific article published on 8 June 2012

Influence of Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) polymorphisms on pain sensitivity and clinical response to weak opioid analgesics

scientific article published on 11 June 2013

Influence of DRD2 polymorphisms on the clinical outcomes of patients with schizophrenia

scientific article published in August 2011

Inhibitory effects of cytochrome P450 enzymes CYP2C8, CYP2C9, CYP2C19 and CYP3A4 by Labisia pumila extracts ⬇️

scientific article published on July 31, 2012

Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6) allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations

scientific article published on 27 January 2014

Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism

scientific article published in April 2006

Methadone Maintenance Therapy (MMT) in Malaysia: An observational clinical study

scientific article published in 2017

Method development and validation of a high-performance liquid chromatographic method for tramadol in human plasma using liquid-liquid extraction.

scientific article

Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract

scientific article published on December 2010

Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography

scientific article published on December 2010

Prevalence and Correlates of HIV and Hepatitis C Virus Infections and Risk Behaviors among Malaysian Fishermen

scientific article

Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males

scientific article

Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT).

scientific article published on 10 June 2016

Relationship between CYP2B6*6 and cold pressor pain sensitivity in opioid dependent patients on methadone maintenance therapy (MMT).

scientific article

Relationship between Type A and B personality and debrisoquine hydroxylation capacity

scientific article published in June 2004

Relationship between cold pressor pain-sensitivity and sleep quality in opioid-dependent males on methadone treatment

scientific article published on 9 April 2015

Role of pharmacodiagnostic of CYP2C9 variants in the optimization of warfarin therapy in Malaysia: a 6-month follow-up study

scientific article published in June 2008

Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia

scientific article published in June 2007

Sleep quality in opioid-naive and opioid-dependent patientson methadone maintenance therapy in Malaysia

scientific article

Standard CYP2D6 genotyping procedures fail for the CYP2D6*5 and duplication alleles when hair roots are used as a source of DNA

scientific article published in March 2003

Substituted spiro [2.3'] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

scientific article published on 26 September 2010

Synthesis and biological evaluation of novel 6, 7-dimethoxy-3-(4-pyridyl)-2,3,3a,4-tetrahydroindeno[1,2-c]pyrazol-2-yl-4-substituted phenylmethanone/ethanone derivatives

scientific article published on 3 June 2011

Synthesis and discovery of novel hexacyclic cage compounds as inhibitors of acetylcholinesterase

scientific article published in July 2011

Synthesis and evaluation of antimycobacterial activity of new benzimidazole aminoesters

scientific article published on 22 June 2013

Synthesis of Highly Functionalised Dispiropyrrolidine Derivatives as Novel Acetylcholinesterase Inhibitors

scientific article published on 31 December 2013

The Effect of CYP2B6, CYP2D6, and CYP3A4 Alleles on Methadone Binding: A Molecular Docking Study

scientific article published in 2013

The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients.

scientific article published in February 2006

Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients.

scientific article published on 30 September 2010

Validation of a high-performance liquid chromatography method for tramadol and o-desmethyltramadol in human plasma using solid-phase extraction

scientific article

Paulina is supported by:

About Paulina

Help