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List of works by Yun-Cai Liu

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

scientific article

Cbl and Cbl-b in T-cell regulation

scientific article published on 01 March 2002

Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.

scientific article published on 15 May 2001

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

scientific article

Conversion of inactive glycosylation inhibiting factor to bioactive derivatives by modification of a SH group.

scientific article published in January 1997

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

scientific article

Differential regulation of the B cell receptor-mediated signaling by the E3 ubiquitin ligase Cbl.

scientific article

Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z.

scientific article

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

scientific article published on 6 February 2018

E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity.

scientific article published in June 2015

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

scientific article published in August 2004

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

scientific article published on September 2005

IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis

scientific article published on 11 May 2015

Immune Regulation by Ubiquitin Tagging as Checkpoint Code.

scientific article published on 20 September 2017

Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch

scientific article

Immune regulation by ubiquitin conjugation.

scientific article published on January 2006

Immunity by ubiquitylation: a reversible process of modification

scientific article

Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect.

scientific article published in May 2006

In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation

scientific article

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells

scientific article

Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation

scientific article published on 01 September 2004

Itch expression by Treg cells controls Th2 inflammatory responses.

scientific article published on 25 October 2013

Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1.

scientific article published on 07 October 2009

Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling

scientific article published on December 24, 2012

Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase.

scientific article

Negative regulation of T cell antigen receptor-mediated Crk-L-C3G signaling and cell adhesion by Cbl-b.

scientific article published on 15 April 2003

Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation.

scientific article published on January 2006

Processing of a fusion protein by endoprotease in COS-1 cells for secretion of mature peptide by using a chimeric expression vector.

scientific article published on October 1993

Production of bioactive salmon calcitonin from the nonendocrine cell lines COS-7 and CHO

scientific article published on 01 January 1997

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

scientific article

Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.

scientific article published on January 1997

Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice

scientific article published on 28 September 2015

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

scientific article

Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells

scientific article (publication date: 5 January 2001)

Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex

scientific article published on May 20, 2013

Requirement of posttranslational modifications for the generation of biologic activity of glycosylation-inhibiting factor.

scientific article published in November 1994

SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex

scientific article published on February 2016

T follicular helper cells, T follicular regulatory cells and autoimmunity.

scientific article published on 29 December 2015

The E3 ligase Itch in immune regulation and beyond.

scientific article published on July 2015

The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation

scientific article published on 21 November 2018

The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control

scientific article published on 23 May 2019

The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR.

scientific article published on 20 June 2018

The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

scientific article

The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1

scientific journal article

The c-kit receptor transduces the stem cell factor-triggered growth signal in murine interleukin-3-dependent cell line.

scientific article published on January 1994

The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function

scientific article

The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch

scientific article (publication date: 22 March 2002)

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

scientific article

The ubiquitin system in immune regulation.

scientific article published on January 2014

The ubiquitin-protein ligase Itch regulates p73 stability

scientific article

To go or not to go: the "itchy" effect on the destiny of hematopoietic stem cells.

scientific article

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

scientific article

Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation

scientific article

Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability.

scientific article published on 12 March 2014

Vav-induced activation of the human IFN-γ gene promoter is mediated by upregulation of AP-1 activity

article