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List of works by Sylvie Chalon

(E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.

scientific article published on 19 September 2007

A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: pharmacological evaluation and PET experiments.

scientific article published in January 1999

ADAM is an effective tool for in vivo study of serotonergic function: validation in rat models.

scientific article published in May 2004

Alpha-7 nicotinic acetylcholine receptor agonist treatment in a rat model of Huntington's disease and involvement of heme oxygenase-1.

scientific article published in April 2018

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study.

scientific article published on 16 January 2015

An iodinated derivative of moclobemide as potential radioligand for brain MAO-A exploration

scientific article published on 01 January 1996

Antenatal bacterial endotoxin sensitizes the immature rat brain to postnatal excitotoxic injury

scientific article

Assessment of the Protection of Dopaminergic Neurons by an α7 Nicotinic Receptor Agonist, PHA 543613 Using [(18)F]LBT-999 in a Parkinson's Disease Rat Model

scientific article published on 2 September 2015

Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism

scientific article published on 28 December 2009

Brain plasticity from fundamental research to clinic

scientific article published on 13 March 2018

Cerebral asymmetry and behavioral lateralization in rats chronically lacking n-3 polyunsaturated fatty acids.

scientific article published on 25 July 2005

Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia

scientific article published in January 1998

Cholinergic nicotinic receptor involvement in movement disorders associated with Lewy body diseases. An autoradiography study using [(125)I]alpha-conotoxinMII in the striatum and thalamus.

scientific article published in February 2005

Chronic dietary n-3 polyunsaturated fatty acids deficiency affects the fatty acid composition of plasmenylethanolamine and phosphatidylethanolamine differently in rat frontal cortex, striatum, and cerebellum

scientific journal article

Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex

scientific article published on 01 April 2000

Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study.

scientific article

DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization

scientific article

Design of α7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [(18)F] quinuclidine derivative

scientific article

Design of α7 nicotinic acetylcholine receptor ligands using the (het)Aryl-1,2,3-triazole core: Synthesis, in vitro evaluation and SAR studies

scientific article published on 10 November 2015

Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE

scientific article published on 03 September 2010

Detection of Neuroinflammation in a Rat Model of Subarachnoid Hemorrhage Using [18F]DPA-714 PET Imaging

scientific article published on 26 April 2016

Drug Delivery Systems for Imaging and Therapy of Parkinson's Disease

scientific article published on 30 December 2015

Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

scientific article published on 11 April 2008

Effect of a diet-induced n-3 PUFA depletion on cholinergic parameters in the rat hippocampus.

scientific article published on 16 May 2003

Effects of 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus on the antidepressant-like action of tramadol in the unpredictable chronic mild stress in mice

scientific article published on 26 June 2008

Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum

scientific article published on 12 December 2011

Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation

scientific article published on 7 June 2008

Evaluation of prion deposits and microglial activation in scrapie-infected mice using molecular imaging probes

scientific article published in December 2010

Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter

scientific article published on 01 December 2007

Expression of Phenotypic Astrocyte Marker Is Increased in a Transgenic Mouse Model of Alzheimer's Disease versus Age-Matched Controls: A Presymptomatic Stage Study.

scientific article published on 08 September 2016

Extensive exploration of a novel rat model of Parkinson's disease using partial 6-hydroxydopamine lesion of dopaminergic neurons suggests new therapeutic approaches

scientific article published on 12 November 2018

Fetal exposure to teratogens: evidence of genes involved in autism

scientific article

Hypoxic preconditioning reduces apoptosis in a rat model of immature brain hypoxia-ischaemia

scientific article published in August 2003

IMPY, a potential beta-amyloid imaging probe for detection of prion deposits in scrapie-infected mice

scientific article published on 20 December 2007

Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.

scientific article

Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.

scientific article published on 19 November 2007

In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999.

scientific article published on 8 October 2013

Involvement of alpha6/alpha3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy bodies: [(125)I]-alpha-conotoxin MII binding in the thalamus and striatum.

scientific article published in December 2004

Iododerivative of pargyline: A potential tracer for the exploration of monoamine oxidase sites by SPECT

scientific article published on 01 August 1995

Is unpredictable chronic mild stress (UCMS) a reliable model to study depression-induced neuroinflammation?

scientific article published on 20 March 2012

Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice

scientific article

Longitudinal Changes in Brain Metabolic Activity after Withdrawal from Escalation of Cocaine Self-Administration.

scientific article published on 29 May 2017

Longitudinal PET Imaging of α7 Nicotinic Acetylcholine Receptors with [18F]ASEM in a Rat Model of Parkinson's Disease

scientific article published on 01 April 2020

Longitudinal and parallel monitoring of neuroinflammation and neurodegeneration in a 6-hydroxydopamine rat model of Parkinson's disease

scientific article

MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood.

scientific article published on 25 March 2009

Maternal exposure to LPS induces hypomyelination in the internal capsule and programmed cell death in the deep gray matter in newborn rats

scientific article published in March 2006

Maternal exposure to lipopolysaccharide leads to transient motor dysfunction in neonatal rats

scientific article published on 27 February 2013

Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway

scientific article published on 21 July 2016

Microdialysis as a tool for in vivo study of dopamine transporter function in rat brains.

scientific article published in November 2000

Molecular imaging of neuroinflammation in preclinical rodent models using positron emission tomography.

scientific article published on 18 November 2016

Monoaminergic neurotransmission and brain dysfunctions in the newborn

scientific article published on 01 January 1999

Motor behaviour deficits and their histopathological and functional correlates in the nigrostriatal system of dopamine transporter knockout mice.

scientific article

Multiinjection approach for D2 receptor binding quantification in living rats using [11C]raclopride and the beta-microprobe: crossvalidation with in vitro binding data.

scientific article

Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents

scientific article published in March 2002

Neuroinflammation and β amyloid deposition in Alzheimer's disease: in vivo quantification with molecular imaging

scientific article published on October 2013

Neuroprotection by neuropeptide Y in cell and animal models of Parkinson's disease.

scientific article

Neuroprotection of nerve growth factor-loaded microspheres on the D2 dopaminergic receptor positive-striatal neurones in quinolinic acid-lesioned rats: a quantitative autoradiographic assessment with iodobenzamide

scientific article published in July 2000

Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model

scientific article

Ontogeny of the dopamine and serotonin transporters in the rat brain: an autoradiographic study

scientific article

Oxidative stress is related to the deleterious effects of heme oxygenase-1 in an in vivo neuroinflammatory rat model

scientific article published on 5 March 2013

PET and SPECT exploration of central monoaminergic transporters for the development of new drugs and treatments in brain disorders.

scientific article

PET tracers for imaging brain α7 nicotinic receptors: an update

scientific article published on 11 September 2015

Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease

scientific article published on 10 March 2008

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

scientific article published on January 2003

Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission.

scientific article

Prenatal MDMA exposure delays postnatal development in the rat: a preliminary study

scientific article published on 18 March 2010

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats

scientific article

Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.

scientific article published on July 2003

Protection of dopaminergic nigrostriatal afferents by GDNF delivered by microspheres in a rodent model of Parkinson's disease

scientific article published on June 2002

Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport

scientific article

Relevance of different striatal markers in assessment of the MPP+-induced dopaminergic nigrostriatal injury in rat.

scientific article published in February 2002

Ropinirole versus L-DOPA effects on striatal opioid peptide precursors in a rodent model of Parkinson's disease: implications for dyskinesia

scientific article

Segmentation of dynamic PET images with kinetic spectral clustering

scientific article published on 13 September 2013

Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat.

scientific article published on May 2004

Spatio-temporal diffusion of dynamic PET images

scientific article published on 21 September 2011

Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

scientific article published in March 2002

Synthesis and characterization of [125I]N-(2-aminoethyl)-4-iodobenzamide as a selective monoamine oxidase B inhibitor

scientific article published on 01 July 1995

Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands.

scientific article published on 3 March 2006

Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands.

scientific article

Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective co

scientific article published in April 1997

Synthesis of 4′-Iodo-5-methoxyvalerophenone O-(2-aminoethyl)oxime as an agent for exploration of serotoninergic transporter

scientific article published on 01 February 1995

Synthesis of tropane and nortropane analogues with phenyl substitutions as serotonin transporter ligands.

scientific article

Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET.

scientific article

The role of fatty acids in the treatment of ADHD.

scientific article published on 26 August 2009

The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component.

scientific article

Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease

scientific article published on December 2003

Toxicity of MPTP on neurotransmission in three mouse models of Parkinson's disease.

scientific article published on 16 October 2012

Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT.

scientific article published in May 1998

Variational segmentation of vector-valued images with gradient vector flow.

scientific article published on 4 September 2014

mRNA D(2) dopaminergic receptor expression after hypoxia-ischemia in rat immature brain

scientific article published in July 2001

n-3 polyunsaturated fatty acid deficiency and dopamine metabolism in the rat frontal cortex

scientific article

n-3 polyunsaturated fatty acid supplementation reverses stress-induced modifications on brain monoamine levels in mice.

scientific article published on 8 November 2007

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