List of works - Eva Dimitriadis

Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

scientific article

Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy.

scholarly article

Chondroitin sulfate proteoglycan protein is stimulated by interleukin 11 and promotes endometrial epithelial cancer cell proliferation and migration.

scientific article published on 13 January 2017

Complex regulation of decidualization: a role for cytokines and proteases--a review.

scientific article

Corin, an enzyme with a putative role in spiral artery remodeling, is up-regulated in late secretory endometrium and first trimester decidua.

scientific article published on 21 February 2013

Cytokines and chemokines during human embryo implantation: roles in implantation and early placentation.

scientific article published on November 2007

Cytokines in Implantation

scientific article published in 2000

Cytokines, chemokines and growth factors in endometrium related to implantation.

scientific article

Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation.

scientific article

Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

scientific article published on 01 April 2019

Dynamic changes in hyperglycosylated human chorionic gonadotrophin throughout the first trimester of pregnancy and its role in early placentation.

scientific article published on 04 March 2015

Effects of Estrogens on Adipokines and Glucose Homeostasis in Female Aromatase Knockout Mice

scientific article published on 28 August 2015

Effects of gefitinib, an epidermal growth factor receptor inhibitor, on human placental cell growth

scientific article published on October 2013

Facilitation of decidualization by locally produced ghrelin in the human endometrium

scientific article

Fetal-maternal communication: the role of Notch signalling in embryo implantation

scientific article

Fibulin-5 is upregulated in decidualized human endometrial stromal cells and promotes primary human extravillous trophoblast outgrowth

scientific article published on 21 October 2015

Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade

scientific article published on 18 December 2015

Formyl peptide receptor-2 is decreased in fetal growth restriction and contributes to placental dysfunction.

scientific article published on 20 December 2017

Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage.

scientific article published on 24 January 2014

Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

scientific article published on 23 July 2018

Galectin-7 is important for normal uterine repair following menstruation.

scientific article published on 29 April 2014

Galectin-7 serum levels are altered prior to the onset of pre-eclampsia

scientific article published on 31 January 2014

Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion

scientific article

Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity

scientific article published on 23 February 2011

Human extravillous trophoblast invasion: intrinsic and extrinsic regulation

scientific article

IL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development

scientific article published on 11 April 2003

IL11 antagonist inhibits uterine stromal differentiation, causing pregnancy failure in mice.

scientific article

Immune Modulators of Implantation and Placental Development— A Workshop Report

article

Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window.

scientific article

Interleukin 1 beta is induced by interleukin 11 during decidualization of human endometrial stromal cells, but is not released in a bioactive form

scientific article published on 24 July 2006

Interleukin 11 Signaling Components Signal Transducer and Activator of Transcription 3 (STAT3) and Suppressor of Cytokine Signaling 3 (SOCS3) Regulate Human Endometrial Stromal Cell Differentiation

scientific article published in August 2006

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization.

scientific article published on 13 January 2010

Interleukin 11 inhibits human trophoblast invasion indicating a likely role in the decidual restraint of trophoblast invasion during placentation.

scientific article

Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice.

scientific article published on 26 November 2017

Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3.

scientific article published on 18 May 2012

Interleukin 11: similar or opposite roles in female reproduction and reproductive cancer?

scientific article

Interleukin-11 alters placentation and causes preeclampsia features in mice

scientific article

Interleukin-11 and leukemia inhibitory factor regulate the adhesion of endometrial epithelial cells: implications in fertility regulation.

scientific article published on 12 February 2009

Interleukin-11 promotes migration, but not proliferation, of human trophoblast cells, implying a role in placentation

scientific article (publication date: November 2007)

Interleukin-11, IL-11 receptorα and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window

scientific article published in February 2006

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice

scientific article

Leukemia inhibitory factor and interleukin-11: critical regulators in the establishment of pregnancy.

scientific article published on 31 July 2009

Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice

scientific article

Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of metalloproteinases-1 and -2

scientific article published on 20 May 2008

Local regulation of implantation at the human fetal-maternal interface.

scientific article published on January 2010

Localisation of the Notch family in the human endometrium of fertile and infertile women

scientific article published on 18 July 2014

MicroRNA Biogenesis Machinery Is Dysregulated in the Endometrium of Infertile Women Suggesting a Role in Receptivity and Infertility

scientific article published on 30 May 2019

Models for study of human embryo implantation: choice of cell lines?

scientific article published on July 2009

New generation contraceptives: interleukin 11 family cytokines as non-steroidal contraceptive targets ⬇️

scientific article published on January 14, 2011

Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT.

scientific article published on 19 July 2013

Preimplantation human blastocysts release factors that differentially alter human endometrial epithelial cell adhesion and gene expression relative to IVF success.

scientific article published on 10 March 2013

Proteomic analysis identifies interleukin 11 regulated plasma membrane proteins in human endometrial epithelial cells in vitro.

scientific article

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.

scientific article published in April 1998

Relaxin and prostaglandin E(2) regulate interleukin 11 during human endometrial stromal cell decidualization.

scientific article published on 22 March 2005

Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth

scientific article published on 09 July 2019

Review: LIF and IL11 in trophoblast-endometrial interactions during the establishment of pregnancy

scientific article published on 02 February 2010

Society for Reproductive Biology Founders' Lecture 2009. Preparing fertile soil: the importance of endometrial receptivity.

scientific article published in January 2009

Subcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity.

scientific article

Targeting Interleukin-11 Receptor-α Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo.

scientific article published on 4 February 2016

The chrondroitin sulfate proteoglycan (CSPG4) regulates human trophoblast function.

scientific article published on 15 August 2013

The role of leukemia inhibitory factor in tubal ectopic pregnancy.

scientific article published on 13 September 2013

Therapeutically blocking Interleukin-11 Receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

scientific article

Trophoblast function is altered by decidual factors in gestational-dependant manner

scientific article published on 26 March 2019

miR-29c overexpression and COL4A1 downregulation in infertile human endometrium reduces endometrial epithelial cell adhesive capacity in vitro implying roles in receptivity.

scientific article

List of works by Eva Dimitriadis

Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy.

Chondroitin sulfate proteoglycan protein is stimulated by interleukin 11 and promotes endometrial epithelial cancer cell proliferation and migration.

Complex regulation of decidualization: a role for cytokines and proteases--a review.

Corin, an enzyme with a putative role in spiral artery remodeling, is up-regulated in late secretory endometrium and first trimester decidua.

Cytokines and chemokines during human embryo implantation: roles in implantation and early placentation.

Cytokines in Implantation

Cytokines, chemokines and growth factors in endometrium related to implantation.

Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation.

Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

Dynamic changes in hyperglycosylated human chorionic gonadotrophin throughout the first trimester of pregnancy and its role in early placentation.

Effects of Estrogens on Adipokines and Glucose Homeostasis in Female Aromatase Knockout Mice

Effects of gefitinib, an epidermal growth factor receptor inhibitor, on human placental cell growth

Facilitation of decidualization by locally produced ghrelin in the human endometrium

Fetal-maternal communication: the role of Notch signalling in embryo implantation

Fibulin-5 is upregulated in decidualized human endometrial stromal cells and promotes primary human extravillous trophoblast outgrowth

Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade

Formyl peptide receptor-2 is decreased in fetal growth restriction and contributes to placental dysfunction.

Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage.

Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

Galectin-7 is important for normal uterine repair following menstruation.

Galectin-7 serum levels are altered prior to the onset of pre-eclampsia

Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion

Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity

Human extravillous trophoblast invasion: intrinsic and extrinsic regulation

IL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development

IL11 antagonist inhibits uterine stromal differentiation, causing pregnancy failure in mice.

Immune Modulators of Implantation and Placental Development— A Workshop Report

Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window.

Interleukin 1 beta is induced by interleukin 11 during decidualization of human endometrial stromal cells, but is not released in a bioactive form

Interleukin 11 Signaling Components Signal Transducer and Activator of Transcription 3 (STAT3) and Suppressor of Cytokine Signaling 3 (SOCS3) Regulate Human Endometrial Stromal Cell Differentiation

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization.

Interleukin 11 inhibits human trophoblast invasion indicating a likely role in the decidual restraint of trophoblast invasion during placentation.

Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice.

Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3.

Interleukin 11: similar or opposite roles in female reproduction and reproductive cancer?

Interleukin-11 alters placentation and causes preeclampsia features in mice

Interleukin-11 and leukemia inhibitory factor regulate the adhesion of endometrial epithelial cells: implications in fertility regulation.

Interleukin-11 promotes migration, but not proliferation, of human trophoblast cells, implying a role in placentation

Interleukin-11, IL-11 receptorα and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice

Leukemia inhibitory factor and interleukin-11: critical regulators in the establishment of pregnancy.

Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice

Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of metalloproteinases-1 and -2

Local regulation of implantation at the human fetal-maternal interface.

Localisation of the Notch family in the human endometrium of fertile and infertile women

MicroRNA Biogenesis Machinery Is Dysregulated in the Endometrium of Infertile Women Suggesting a Role in Receptivity and Infertility

Models for study of human embryo implantation: choice of cell lines?

New generation contraceptives: interleukin 11 family cytokines as non-steroidal contraceptive targets ⬇️

Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT.

Preimplantation human blastocysts release factors that differentially alter human endometrial epithelial cell adhesion and gene expression relative to IVF success.

Proteomic analysis identifies interleukin 11 regulated plasma membrane proteins in human endometrial epithelial cells in vitro.

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.

Relaxin and prostaglandin E(2) regulate interleukin 11 during human endometrial stromal cell decidualization.

Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth

Review: LIF and IL11 in trophoblast-endometrial interactions during the establishment of pregnancy

Society for Reproductive Biology Founders' Lecture 2009. Preparing fertile soil: the importance of endometrial receptivity.

Subcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity.

Targeting Interleukin-11 Receptor-α Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo.

The chrondroitin sulfate proteoglycan (CSPG4) regulates human trophoblast function.

The role of leukemia inhibitory factor in tubal ectopic pregnancy.

Therapeutically blocking Interleukin-11 Receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

Trophoblast function is altered by decidual factors in gestational-dependant manner

miR-29c overexpression and COL4A1 downregulation in infertile human endometrium reduces endometrial epithelial cell adhesive capacity in vitro implying roles in receptivity.