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List of works by Yiu Wa Kwan

14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery.

scientific article published on 30 June 2010

A lab-in-a-droplet bioassay strategy for centrifugal microfluidics with density difference pumping, power to disc and bidirectional flow control.

scientific article published in September 2013

A review of the pharmacological effects of Arctium lappa (burdock).

scientific article published on 28 October 2010

Activation of the iberiotoxin-sensitive BKCa channels by salvianolic acid B of the porcine coronary artery smooth muscle cells

scientific article published on 27 July 2006

Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytes

scientific article (publication date: 2013)

Allergen screening bioassays: recent developments in lab-on-a-chip and lab-on-a-disc systems.

scientific article

Allergy Testing and Drug Screening on an ITO-Coated Lab-on-a-Disc

scientific article published on 27 February 2016

Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species.

scientific article

An in vitro study of histamine on the pulmonary artery of the Wistar-Kyoto and spontaneously hypertensive rats.

scientific article

An integrated lab-on-a-disc for automated cell-based allergen screening bioassays.

scientific article

Angiogenic effect of saponin extract from Panax notoginseng on HUVECs in vitro and zebrafish in vivo.

scientific article

Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors

scientific article published on 4 November 2009

Antrodia camphorata Increases Insulin Secretion and Protects from Apoptosis in MIN6 Cells.

scientific article published on 21 March 2016

Automated real-time detection of drug-resistant Mycobacterium tuberculosis on a lab-on-a-disc by Recombinase Polymerase Amplification.

scientific article published on 2 January 2018

Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis.

scientific article

Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa).

scientific article

Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC

scientific article

Cerebral vasodilator properties of Danshen and Gegen: a study of their combined efficacy and mechanisms of actions

scientific article published on 2 November 2013

Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods

scientific article

Comparative Antifibrillatory Effects of d- and dl-Sotalol in Normal and Ischaemic Ventricular Muscle of the Cat ⬇️

scientific article published on 01 February 1990

Comparison of the vascular relaxant effects of ATP-dependent K+ channel openers on aorta and pulmonary artery isolated from spontaneously hypertensive and Wistar-Kyoto rats

scientific article published on 01 January 1999

Complementary Medicine for the Modification of Risk Factors for Cognitive Impairment.

scientific article published on 19 February 2017

Constrictor and dilator effects of angiotensin II on cerebral arterioles.

scientific article published on 3 November 2005

Contribution of glibenclamide-sensitive, ATP-dependent K+ channel activation to acetophenone analogues-mediated in vitro pulmonary artery relaxation of rat.

scientific article

Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions ⬇️

scientific article published on September 29, 2012

Diabetes Mellitus, Cognitive Impairment, and Traditional Chinese Medicine

scientific article published on 28 April 2015

Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin

scientific article published on 21 August 2017

Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isofor

scientific article published on 18 January 2012

Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies

scientific article published on 14 February 2015

Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis.

scientific article published on 22 August 2013

Endothelium-independent relaxation to raloxifene in porcine coronary artery

scientific article published on 20 October 2006

Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes.

scientific article published on 25 October 2012

Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics.

scientific article published on 16 August 2017

Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer.

scientific article published on January 2010

Exosomes in Inflammation and Inflammatory Disease

scientific article published on 22 March 2019

Extract of Scutellaria baicalensis Georgi Root Exerts Protection Against Myocardial Ischemia-Reperfusion Injury in Rats

scientific article published on 01 January 2011

Folic acid consumption reduces resistin level and restores blunted acetylcholine-induced aortic relaxation in obese/diabetic mice

scientific article

Folic acid supplementation modifies beta-adrenoceptor-mediated in vitro lipolysis of obese/diabetic (+db/+db) mice.

scientific article published on 13 July 2009

Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway

scientific article

Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways.

scientific article published on 30 June 2009

G-protein coupled receptor 55 agonists increase insulin secretion through inositol trisphosphate-mediated calcium release in pancreatic β-cells

scientific article published on 01 May 2019

GmPHD5 acts as an important regulator for crosstalk between histone H3K4 di-methylation and H3K14 acetylation in response to salinity stress in soybean ⬇️

scientific article published on December 15, 2011

High salt intake abolishes AT(2)-mediated vasodilation of pial arterioles in rats

scientific article published on 01 July 2011

Identification of histone methylation multiplicities patterns in the brain of senescence-accelerated prone mouse 8.

scientific article published on 12 May 2009

Immunoassays using polypeptide conjugate binders with tuned affinity

scientific article published on 01 October 2010

Impairment of the vascular relaxation and differential expression of caveolin-1 of the aorta of diabetic +db/+db mice

scientific article published on 13 July 2006

In vitro vitamin K(2) and 1α,25-dihydroxyvitamin D(3) combination enhances osteoblasts anabolism of diabetic mice.

scientific article published on 6 October 2015

Inhibition of cardiac L-type calcium channels by quaternary amlodipine: implications for pharmacokinetics and access to dihydropyridine binding site.

scientific article published in January 1995

Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine.

scientific article published on 4 July 2016

Inhibitory effects of epoxyeicosatrienoic acids on volume-activated chloride channels in rat mesenteric arterial smooth muscle.

scientific article published on 2 September 2008

Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells.

scientific article

Involvements of calcium channel and potassium channel in Danshen and Gegen decoction induced vasodilation in porcine coronary LAD artery

scientific article published on 11 August 2012

Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells

scientific article published on 15 September 2017

Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery

scientific article published on 20 November 2011

Mechanisms of the relaxant effect of a danshen and gegen formulation on rat isolated cerebral basilar artery.

scientific article published on 17 August 2010

Mechanisms responsible for the in vitro relaxation of ligustrazine on porcine left anterior descending coronary artery ⬇️

scientific article published on May 16, 2003

Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae

article

Miltirone Is a Dual Inhibitor of P-Glycoprotein and Cell Growth in Doxorubicin-Resistant HepG2 Cells

scientific article published on 4 September 2015

Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery.

scientific article published on November 2010

Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells

scientific article published on 05 July 2006

Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes

scientific article published on 27 April 2012

Noninvasive Real-Time Characterization of Renal Clearance Kinetics in Diabetic Mice after Receiving Danshensu Treatment.

scientific article published on 12 February 2018

Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice.

scientific article

Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic β-cells

scientific article published on 15 January 2019

Potentiation of EDHF-mediated relaxation by chloride channel blockers ⬇️

scientific article published on September 13, 2010

Presynaptic modulation by L-glutamate and GABA of sympathetic co-transmission in rat isolated vas deferens.

scientific article published on June 1996

Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors.

scientific article

Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries

scientific article published on 04 May 2015

Relaxation effect of abacavir on rat basilar arteries.

scientific article published on 8 April 2015

Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.

scientific article published in March 2003

Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery.

scientific article published in March 2009

Salvianolic acid B, an aqueous component of danshen (Salvia miltiorrhiza), relaxes rat coronary artery by inhibition of calcium channels

scientific article published on 23 September 2006

Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats

scientific article published on 01 October 2012

Serum proteomic, peptidomic and metabolomic profiles in myasthenia gravis patients during treatment with Qiangji Jianli Fang.

scientific article

Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography

scientific article (publication date: July 1999)

Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish

scientific article published on 04 May 2018

Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity

scientific article published on 01 November 1993

Systematic analysis of human lysine acetylation proteins and accurate prediction of human lysine acetylation through bi-relative adapted binomial score Bayes feature representation.

scientific article published in November 2012

TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells

scientific article published on 12 October 2016

Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes

scientific article published on 06 September 2011

The angiogenic effects of Angelica sinensis extract on HUVEC in vitro and zebrafish in vivo

scientific article published on 01 January 2008

Uptake and protective effects of ergothioneine in human endothelial cells

scientific article published on 14 July 2014

VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation.

scientific article published on 16 September 2014

Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine.

scientific article

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