List of works - Erwan Poupon

"Squalenoylcurcumin" nanoassemblies as water-dispersible drug candidates with antileishmanial activity

scientific article published on 18 December 2014

A unified bioinspired "aplysinopsin cascade": total synthesis of (±)-tubastrindole B and related biosynthetic congeners

scientific article published on 15 September 2014

Alkaloids from Rutaceae: activities of canthin-6-one alkaloids and synthetic analogues on glioblastoma stems cells

article published in 2012

An Expeditious Total Synthesis of the Natural Stereomeric Mixture of Stenusine Following a Possible Biogenetic Pathway We are grateful to Prof. Dr. Dieter Enders for fruitful discussions

scientific article published on 01 April 2000

An Unprecedented Blue Chromophore Found in Nature using a "Chemistry First" and Molecular Networking Approach: Discovery of Dactylocyanines A-H.

scientific article published on 16 August 2017

Analogues of cytotoxic squamocin using reliable reactions: new insights into the reactivity and role of the α,β-unsaturated lactone of the annonaceous acetogenins

Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues.

scientific article published in June 2005

Antiproliferative activity of trans-avicennol from Zanthoxylum chiloperone var. angustifolium against human cancer stem cells.

scientific article

Biodegradable polymeric nanoformulation based on the antiprotozoal canthin-6-one

scholarly article by José L Arias et al published 25 September 2011 in Journal of Nanoparticle Research

Bioelectrochemical monitoring of soluble guanylate cyclase inhibition by the natural β-carboline canthin-6-one

scholarly article by Antonio Doménech-Carbó et al published April 2017 in Journal of Molecular Structure

Biogenetic hypothesis and first steps towards a biomimetic synthesis of haouamines

scientific article published on 19 December 2006

Biogenetic relationships between Annonaceous acetogenins: squamocin is not a precursor of chamuvarinin based on a semisynthetic study

scientific article published on 06 February 2007

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for Enantioselective Total Synthesis of Mavacuran Alkaloids

scientific article published on 21 June 2019

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Enantioselective Total Synthesis of Mavacuran Alkaloids

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Total Synthesis of (-)-17-nor-Excelsinidine

scientific article published on 23 April 2018

Biomimetic one-step access to nitraramine from simple C5 units. Revision of the previously reported structure of epinitraramine to nitraramine

scientific article published on 01 June 2005

Biomimetic synthesis of tangutorine following new biogenetic proposals

scientific article published on 01 May 2009

Biomimetically relevant self-condensations of C5 units derived from lysine.

scientific article published in April 2010

Biosynthesis and biomimetic synthesis of alkaloids isolated from plants of the Nitraria and Myrioneuron genera: an unusual lysine-based metabolism

scientific article

Biotransformations versus chemical modifications: new cytotoxic analogs of marine sesquiterpene ilimaquinone

scientific article published in 2016

CANPA: Computer-Assisted Natural Products Anticipation

scientific article published on 29 April 2019

CANPA: Computer-Assisted Natural Products Anticipation ⬇️

scientific article published on 15 August 2019

Chemoinformatic Exploration of “Bioinspired Metabolomes” Illuminates Diacetyl Assembly Pathways Toward Nesteretal A-Like Cage Molecules

scientific article published in 2022

Chiral nonracemic synthesis and reactivity of two new endocyclic enamines in the phenyloxazolopiperidine series

scientific article published on 01 May 2000

Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research

scientific article published on 03 April 2019

Composition, and antimicrobial and remarkable antiprotozoal activities of the essential oil of rhizomes of Aframomum sceptrum K. Schum. (Zingiberaceae).

scientific article published on April 2011

DNA-Templated [2+2] Photocycloaddition: A Straightforward Entry into the Aplysinopsin Family of Natural Products

scientific article published on 02 August 2018

Effects of canthin-6-one alkaloids from Zanthoxylum chiloperone on Trypanosoma cruzi-infected mice

scientific article published on 29 July 2006

Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers.

scientific article published on 25 May 2016

Extraction, hemisynthesis, and synthesis of canthin-6-one analogues. Evaluation of their antifungal activities

scientific article published in November 2005

Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one.

scientific article published on 18 March 2015

Highly cytotoxic and neurotoxic acetogenins of the Annonaceae: new putative biological targets of squamocin detected by activity-based protein profiling.

scientific article

In silico anticipation of metabolic pathways extended to organic chemistry reactions: a case study with caffeine alkaline hydrolysis and the origin of camellimidazoles

scientific article published on 29 July 2020

Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges

scientific article published on 06 December 2018

Labdane diterpenoids from Aframomum sceptrum: NMR study and antiparasitic activities

scientific article published on 20 May 2011

Manipulating Simple Reactive Chemical Units: Fishing for Alkaloids from Complex Mixtures

scientific article published on 08 April 2015

Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species

scientific article published on 24 February 2020

Natural products targeting strategies involving molecular networking: different manners, one goal

scientific article published on 29 May 2019

New building blocks for tackling the synthesis of polyhydroxylated piperidines: expeditious synthesis of amino derivatives in the 1-deoxynojirimycin series

scientific article published on 01 October 2000

New piperidine scaffolds via nucleophilic reactivity of (-)-phenyloxazolopiperidine

scientific article

Particular behavior of ‘C6C2 units’ in the Chichibabin pyridine synthesis and biosynthetic implications

Phenylpropane as an Alternative Dearomatizing Unit of Indoles: Discovery of Inaequalisines A and B Using Substructure-Informed Molecular Networking

scientific article published on 20 July 2020

Phytoelectrochemical analysis of Zanthoxylum chiloperone.

scientific article

Pleiokomenines A and B: Dimeric Aspidofractinine Alkaloids Tethered with a Methylene Group.

scientific article published on 7 November 2017

Pyrone and unusually furanone-substituted flavones from the leaves of Hoslundia opposita

scientific article published on 4 September 2012

Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations ⬇️

scientific article published in 2022

Quinone Sesquiterpenes: A Challenge for the Development of a New Synthetic Methodology

scientific article published in 2005

Remarkable substituent effect: beta-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III.

scientific article

Retraction. Biogenetic hypothesis and first steps towards a biomimetic synthesis of haouamines

scientific article published on 01 January 2008

Revisiting Previously Investigated Plants: A Molecular Networking-Based Study of Geissospermum laeve.

scientific article

Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.

scientific article

Solid-Phase Extraction Embedded Dialysis (SPEED), an Innovative Procedure for the Investigation of Microbial Specialized Metabolites

scientific article published in 2021

Solid-State Electrochemical Assay of Heme-Binding Molecules for Screening of Drugs with Antimalarial Potential

scientific article published on 02 April 2013

Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties onC. elegans

Spontaneous biomimetic formation of (±)-dictazole B under irradiation with artificial sunlight

scientific article published on 09 May 2014

Spontaneous formation of nitrarine and polycyclic skeletons related to Nitraria indolic alkaloids under non-enzymic conditions.

scientific article

Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures

scientific article published on 16 July 2021

Synthesis of (-)-ilimaquinone via a radical decarboxylation and quinone addition reaction

scientific article published on 01 March 2002

Synthesis of polyhydroxylated piperidines and evaluation as glycosidase inhibitors

scientific article published on 01 October 2004

The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum

Theionbrunonines A and B: Dimeric Vobasine Alkaloids Tethered by a Thioether Bridge from Mostuea brunonis

scientific article published on 10 October 2018

Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings.

scientific article published on 27 February 2017

Unified synthesis of quinone sesquiterpenes based on a radical decarboxylation and quinone addition reaction

scientific article published in October 2002

Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana ⬇️

scientific article published on 26 September 2021

Zanthoxylum chiloperone leaves extract: first sustainable Chagas disease treatment

scientific article published on 4 December 2010

List of works by Erwan Poupon

"Squalenoylcurcumin" nanoassemblies as water-dispersible drug candidates with antileishmanial activity

A unified bioinspired "aplysinopsin cascade": total synthesis of (±)-tubastrindole B and related biosynthetic congeners

Alkaloids from Rutaceae: activities of canthin-6-one alkaloids and synthetic analogues on glioblastoma stems cells

An Expeditious Total Synthesis of the Natural Stereomeric Mixture of Stenusine Following a Possible Biogenetic Pathway We are grateful to Prof. Dr. Dieter Enders for fruitful discussions

An Unprecedented Blue Chromophore Found in Nature using a "Chemistry First" and Molecular Networking Approach: Discovery of Dactylocyanines A-H.

Analogues of cytotoxic squamocin using reliable reactions: new insights into the reactivity and role of the α,β-unsaturated lactone of the annonaceous acetogenins

Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues.

Antiproliferative activity of trans-avicennol from Zanthoxylum chiloperone var. angustifolium against human cancer stem cells.

Biodegradable polymeric nanoformulation based on the antiprotozoal canthin-6-one

Bioelectrochemical monitoring of soluble guanylate cyclase inhibition by the natural β-carboline canthin-6-one

Biogenetic hypothesis and first steps towards a biomimetic synthesis of haouamines

Biogenetic relationships between Annonaceous acetogenins: squamocin is not a precursor of chamuvarinin based on a semisynthetic study

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for Enantioselective Total Synthesis of Mavacuran Alkaloids

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Enantioselective Total Synthesis of Mavacuran Alkaloids

Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Total Synthesis of (-)-17-nor-Excelsinidine

Biomimetic one-step access to nitraramine from simple C5 units. Revision of the previously reported structure of epinitraramine to nitraramine

Biomimetic synthesis of tangutorine following new biogenetic proposals

Biomimetically relevant self-condensations of C5 units derived from lysine.

Biosynthesis and biomimetic synthesis of alkaloids isolated from plants of the Nitraria and Myrioneuron genera: an unusual lysine-based metabolism

Biotransformations versus chemical modifications: new cytotoxic analogs of marine sesquiterpene ilimaquinone

CANPA: Computer-Assisted Natural Products Anticipation

CANPA: Computer-Assisted Natural Products Anticipation ⬇️

Chemoinformatic Exploration of “Bioinspired Metabolomes” Illuminates Diacetyl Assembly Pathways Toward Nesteretal A-Like Cage Molecules

Chiral nonracemic synthesis and reactivity of two new endocyclic enamines in the phenyloxazolopiperidine series

Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research

Composition, and antimicrobial and remarkable antiprotozoal activities of the essential oil of rhizomes of Aframomum sceptrum K. Schum. (Zingiberaceae).

DNA-Templated [2+2] Photocycloaddition: A Straightforward Entry into the Aplysinopsin Family of Natural Products

Effects of canthin-6-one alkaloids from Zanthoxylum chiloperone on Trypanosoma cruzi-infected mice

Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers.

Extraction, hemisynthesis, and synthesis of canthin-6-one analogues. Evaluation of their antifungal activities

Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one.

Highly cytotoxic and neurotoxic acetogenins of the Annonaceae: new putative biological targets of squamocin detected by activity-based protein profiling.

In silico anticipation of metabolic pathways extended to organic chemistry reactions: a case study with caffeine alkaline hydrolysis and the origin of camellimidazoles

Insights into the Biosynthesis of Cyclic Guanidine Alkaloids from Crambeidae Marine Sponges

Labdane diterpenoids from Aframomum sceptrum: NMR study and antiparasitic activities

Manipulating Simple Reactive Chemical Units: Fishing for Alkaloids from Complex Mixtures

Molecular Networking Reveals Serpentinine-Related Bisindole Alkaloids from Picralima nitida, a Previously Well-Investigated Species

Natural products targeting strategies involving molecular networking: different manners, one goal

New building blocks for tackling the synthesis of polyhydroxylated piperidines: expeditious synthesis of amino derivatives in the 1-deoxynojirimycin series

New piperidine scaffolds via nucleophilic reactivity of (-)-phenyloxazolopiperidine

Particular behavior of ‘C6C2 units’ in the Chichibabin pyridine synthesis and biosynthetic implications

Phenylpropane as an Alternative Dearomatizing Unit of Indoles: Discovery of Inaequalisines A and B Using Substructure-Informed Molecular Networking

Phytoelectrochemical analysis of Zanthoxylum chiloperone.

Pleiokomenines A and B: Dimeric Aspidofractinine Alkaloids Tethered with a Methylene Group.

Pyrone and unusually furanone-substituted flavones from the leaves of Hoslundia opposita

Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations ⬇️

Quinone Sesquiterpenes: A Challenge for the Development of a New Synthetic Methodology

Remarkable substituent effect: beta-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III.

Retraction. Biogenetic hypothesis and first steps towards a biomimetic synthesis of haouamines

Revisiting Previously Investigated Plants: A Molecular Networking-Based Study of Geissospermum laeve.

Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.

Solid-Phase Extraction Embedded Dialysis (SPEED), an Innovative Procedure for the Investigation of Microbial Specialized Metabolites

Solid-State Electrochemical Assay of Heme-Binding Molecules for Screening of Drugs with Antimalarial Potential

Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties onC. elegans

Spontaneous biomimetic formation of (±)-dictazole B under irradiation with artificial sunlight

Spontaneous formation of nitrarine and polycyclic skeletons related to Nitraria indolic alkaloids under non-enzymic conditions.

Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures

Synthesis of (-)-ilimaquinone via a radical decarboxylation and quinone addition reaction

Synthesis of polyhydroxylated piperidines and evaluation as glycosidase inhibitors

The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum

Theionbrunonines A and B: Dimeric Vobasine Alkaloids Tethered by a Thioether Bridge from Mostuea brunonis

Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings.

Unified synthesis of quinone sesquiterpenes based on a radical decarboxylation and quinone addition reaction

Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana ⬇️

Zanthoxylum chiloperone leaves extract: first sustainable Chagas disease treatment