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List of works by David J. H. Shih

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases

scientific article published on 31 May 2018

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

scientific article published on 25 November 2012

Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas

scientific article published on 14 April 2020

Clonal selection drives genetic divergence of metastatic medulloblastoma

scientific article published on 15 February 2012

Cytogenetic prognostication within medulloblastoma subgroups

scientific article published on 03 February 2014

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Divergent clonal selection dominates medulloblastoma at recurrence

scientific article published on 13 January 2016

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

scientific article

Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity

scientific article

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

scientific article

Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer

scientific article published on 15 January 2022

Gene-expression profiling elucidates molecular signaling networks that can be therapeutically targeted in vestibular schwannoma

scientific article published on 23 September 2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

scientific article

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

scientific article published on 23 March 2020

Heterogeneity within the PF-EPN-B ependymoma subgroup

article

High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis

scientific article

MRI surrogates for molecular subgroups of medulloblastoma.

scientific article published on 15 May 2014

Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.

scientific article published on February 2015

Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy

scientific article published on 14 April 2020

Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

scientific article published on 15 May 2017

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

scientific article

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

scientific article published on 11 March 2016

Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

scientific article published on 6 November 2011

Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

scientific article published on 17 October 2013

Spatial heterogeneity in medulloblastoma

scientific article published on 10 April 2017

Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.

scientific article

Subgroup-specific alternative splicing in medulloblastoma

scientific article

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma

scientific article published on 08 July 2013

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

scientific article published on 31 October 2013

Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases.

scientific article published on 25 September 2013

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma

scientific article

WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma

scientific article

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