Search filters

List of works by Derek J Wilson

A Unique Conformational Distortion Mechanism Drives Lipocalin 2 Binding to Bacterial Siderophores

scientific article published on 28 October 2019

A capillary mixer with adjustable reaction chamber volume for millisecond time-resolved studies by electrospray mass spectrometry.

scientific article published in December 2003

A microfluidic reactor for rapid, low-pressure proteolysis with on-chip electrospray ionization

scientific article

A versatile microfluidic chip for millisecond time-scale kinetic studies by electrospray mass spectrometry

scientific article published on 7 September 2008

An interdomain bridge influences RNA binding of the human La protein

scientific article published on 10 December 2018

Binding interactions in early- and late-stage amyloid aggregates of TTR(105-115)

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

scientific article published on 17 January 2020

Conformer selection and intensified dynamics during catalytic turnover in chymotrypsin

scientific article published on 31 August 2012

Distinct Dynamic Modes Enable the Engagement of Dissimilar Ligands in a Promiscuous Atypical RNA Recognition Motif.

scientific article

Enhanced Binding Affinity via Destabilization of the Unbound State: A Millisecond Hydrogen-Deuterium Exchange Study of the Interaction between p53 and a Pleckstrin Homology Domain.

scientific article published on 11 July 2017

Evidence for an Allosteric S-Nitrosoglutathione Binding Site in S-Nitrosoglutathione Reductase (GSNOR)

scientific article published on 13 November 2019

Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity

scientific article published on 05 August 2020

HDX-MS and deletion analysis of the type 4 secretion system protein TraF from the Escherichia coli F plasmid

scientific article published on 20 January 2016

HDX-MS: An Analytical Tool to Capture Protein Motion in Action

scientific article published on 17 July 2020

Hydrogen-Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin

scientific article published on 03 January 2019

Hydrogen/deuterium scrambling during quadrupole time-of-flight MS/MS analysis of a zinc-binding protein domain.

scientific article published on January 2007

Impact of Cardiolipin and Phosphatidylcholine Interactions on the Conformational Ensemble of Cytochrome c

scientific article published on 12 August 2019

Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding.

scientific article

Kinetic unfolding mechanism of the inducible nitric oxide synthase oxygenase domain determined by time-resolved electrospray mass spectrometry.

scientific article published in February 2005

Measuring dynamics in weakly structured regions of proteins using microfluidics-enabled subsecond H/D exchange mass spectrometry

scientific article published on 6 April 2012

Mechanistic studies on enzymatic reactions by electrospray ionization MS using a capillary mixer with adjustable reaction chamber volume for time-resolved measurements.

scientific article published on May 2004

Pulsed hydrogen exchange and electrospray charge-state distribution as complementary probes of protein structure in kinetic experiments: implications for ubiquitin folding.

scientific article

Rapid characterization of structural and functional similarity for a candidate bevacizumab (Avastin) biosimilar using a multipronged mass-spectrometry-based approach

scientific article published on 23 May 2019

Rational manipulation of amyloidogenesis using an atomic level map of peptide-fibril interactions

scientific article published on 01 July 2010

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

scientific article published on 27 June 2019

Specific Disruption of Transthyretin(105–115) Fibrilization Using “Stabilizing” Inhibitors of Transthyretin Amyloidogenesis ⬇️

scientific article published on April 12, 2012

Subunit disassembly and unfolding kinetics of hemoglobin studied by time-resolved electrospray mass spectrometry.

scientific article published in November 2004

Time-Resolved Mass Spectrometry for Monitoring Millisecond Time-Scale Solution-Phase Processes ⬇️

scientific article published on January 1, 2012

Ultrarapid desalting of protein solutions for electrospray mass spectrometry in a microchannel laminar flow device.

scientific article published in November 2005

Understanding and optimizing electrospray ionization techniques for proteomic analysis ⬇️

scientific article published on April 1, 2011

Paulina is supported by:

About Paulina

Help