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List of works by Albert Gough

A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX.

scientific article

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

scientific article

A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens

scientific article published on 14 October 2015

Applications of the microphysiology systems database for experimental ADME-Tox and disease models

scientific article published on 25 March 2020

Automated light microscopy for the study of the brain: cellular and molecular dynamics, development, and tumorigenesis.

scientific article published on May 1997

Biologically Relevant Heterogeneity: Metrics and Practical Insights

scientific article published on 06 January 2017

Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system.

scientific article published on October 1998

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

scientific article published in January 2017

Fluorescent protein biosensors applied to microphysiological systems

scientific article

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

scientific article (publication date: 2014)

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies.

scientific article published in January 2018

In vitro platforms for evaluating liver toxicity

scientific article

Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System.

scientific article

Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.

scientific article published in November 2017

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

scientific article published on January 2017

Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

scientific article published on 14 July 2020

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury

scientific article published in 2023

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

scientific article

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