Search filters

List of works by Lawrence Vernetti

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

scientific article

A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity.

scientific article published on 2 February 2017

A human liver microphysiology platform for investigating physiology, drug safety, and disease models

scientific article

ATP depletion is associated with cytotoxicity of a novel lipid regulator in guinea pig adrenocortical cells

scientific article published on 01 January 1993

Adaptation of an in vitro phospholipidosis assay to an automated image analysis system

scientific article published on 01 January 2007

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

scientific article published in January 2017

Delayed treatment with PTBA analogs reduces postinjury renal fibrosis after kidney injury

scientific article published on 9 December 2015

Design and evaluation of novel glutaminase inhibitors

scientific article

Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.

scientific article published in January 1997

Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.

scientific article published on February 2017

Fluorescent protein biosensors applied to microphysiological systems

scientific article

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

scientific article published on 08 February 2017

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

scientific article (publication date: 2014)

In vitro platforms for evaluating liver toxicity

scientific article

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

scientific article published on January 2017

Selective Alteration of Cytokeratin Intermediate Filament by Cyclosporine A is a Lethal Toxicity in PTK2 Cell Cultures ⬇️

scientific article published on January 1, 1991

Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

scientific article

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury

scientific article published in 2023

The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models

scientific article published on June 2016

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

scientific article

Paulina is supported by:

About Paulina

Help